262 related articles for article (PubMed ID: 20516064)
1. Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity.
Perry JJ; Asaithamby A; Barnebey A; Kiamanesch F; Chen DJ; Han S; Tainer JA; Yannone SM
J Biol Chem; 2010 Aug; 285(33):25699-707. PubMed ID: 20516064
[TBL] [Abstract][Full Text] [Related]
2. Multimerization domains are associated with apparent strand exchange activity in BLM and WRN DNA helicases.
Chen CF; Brill SJ
DNA Repair (Amst); 2014 Oct; 22():137-46. PubMed ID: 25198671
[TBL] [Abstract][Full Text] [Related]
3. A fluorescence-based exonuclease assay to characterize DmWRNexo, orthologue of human progeroid WRN exonuclease, and its application to other nucleases.
Mason PA; Boubriak I; Cox LS
J Vis Exp; 2013 Dec; (82):e50722. PubMed ID: 24378758
[TBL] [Abstract][Full Text] [Related]
4. Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.
Shen JC; Gray MD; Oshima J; Kamath-Loeb AS; Fry M; Loeb LA
J Biol Chem; 1998 Dec; 273(51):34139-44. PubMed ID: 9852073
[TBL] [Abstract][Full Text] [Related]
5. Intrinsic ssDNA annealing activity in the C-terminal region of WRN.
Muftuoglu M; Kulikowicz T; Beck G; Lee JW; Piotrowski J; Bohr VA
Biochemistry; 2008 Sep; 47(39):10247-54. PubMed ID: 18771289
[TBL] [Abstract][Full Text] [Related]
6. The Drosophila orthologue of progeroid human WRN exonuclease, DmWRNexo, cleaves replication substrates but is inhibited by uracil or abasic sites : analysis of DmWRNexo activity in vitro.
Mason PA; Boubriak I; Robbins T; Lasala R; Saunders R; Cox LS
Age (Dordr); 2013 Jun; 35(3):793-806. PubMed ID: 22562358
[TBL] [Abstract][Full Text] [Related]
7. DmWRNexo is a 3'-5' exonuclease: phenotypic and biochemical characterization of mutants of the Drosophila orthologue of human WRN exonuclease.
Boubriak I; Mason PA; Clancy DJ; Dockray J; Saunders RD; Cox LS
Biogerontology; 2009 Jun; 10(3):267-77. PubMed ID: 18956248
[TBL] [Abstract][Full Text] [Related]
8. Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples.
Lachapelle S; Gagné JP; Garand C; Desbiens M; Coulombe Y; Bohr VA; Hendzel MJ; Masson JY; Poirier GG; Lebel M
J Proteome Res; 2011 Mar; 10(3):1216-27. PubMed ID: 21210717
[TBL] [Abstract][Full Text] [Related]
9. Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.
von Kobbe C; Harrigan JA; Schreiber V; Stiegler P; Piotrowski J; Dawut L; Bohr VA
Nucleic Acids Res; 2004; 32(13):4003-14. PubMed ID: 15292449
[TBL] [Abstract][Full Text] [Related]
10. WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
Aggarwal M; Brosh RM
Aging (Albany NY); 2009 Feb; 1(2):219-33. PubMed ID: 20157511
[TBL] [Abstract][Full Text] [Related]
11. The RAD9-RAD1-HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stalling.
Pichierri P; Nicolai S; Cignolo L; Bignami M; Franchitto A
Oncogene; 2012 Jun; 31(23):2809-23. PubMed ID: 22002307
[TBL] [Abstract][Full Text] [Related]
12. DNA secondary structure of the released strand stimulates WRN helicase action on forked duplexes without coordinate action of WRN exonuclease.
Ahn B; Bohr VA
Biochem Biophys Res Commun; 2011 Aug; 411(4):684-9. PubMed ID: 21763283
[TBL] [Abstract][Full Text] [Related]
13. Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing.
Kusumoto R; Dawut L; Marchetti C; Wan Lee J; Vindigni A; Ramsden D; Bohr VA
Biochemistry; 2008 Jul; 47(28):7548-56. PubMed ID: 18558713
[TBL] [Abstract][Full Text] [Related]
14. Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms.
Massip L; Garand C; Labbé A; Perreault E; Turaga RV; Bohr VA; Lebel M
Oncogene; 2010 Mar; 29(10):1486-97. PubMed ID: 19966859
[TBL] [Abstract][Full Text] [Related]
15. Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.
Opresko PL; Laine JP; Brosh RM; Seidman MM; Bohr VA
J Biol Chem; 2001 Nov; 276(48):44677-87. PubMed ID: 11572872
[TBL] [Abstract][Full Text] [Related]
16. Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation.
Karmakar P; Piotrowski J; Brosh RM; Sommers JA; Miller SP; Cheng WH; Snowden CM; Ramsden DA; Bohr VA
J Biol Chem; 2002 May; 277(21):18291-302. PubMed ID: 11889123
[TBL] [Abstract][Full Text] [Related]
17. Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease.
Bird JL; Jennert-Burston KC; Bachler MA; Mason PA; Lowe JE; Heo SJ; Campisi J; Faragher RG; Cox LS
Biogerontology; 2012 Feb; 13(1):49-62. PubMed ID: 21786128
[TBL] [Abstract][Full Text] [Related]
18. Exogenous expression of exonuclease domain-deleted WRN interferes with the repair of radiation-induced DNA damages.
Kashino G; Kodama S; Suzuki K; Matsumoto T; Watanabe M
J Radiat Res; 2005 Dec; 46(4):407-14. PubMed ID: 16394631
[TBL] [Abstract][Full Text] [Related]
19. Nonenzymatic role for WRN in preserving nascent DNA strands after replication stress.
Su F; Mukherjee S; Yang Y; Mori E; Bhattacharya S; Kobayashi J; Yannone SM; Chen DJ; Asaithamby A
Cell Rep; 2014 Nov; 9(4):1387-401. PubMed ID: 25456133
[TBL] [Abstract][Full Text] [Related]
20. Quantitative analysis of WRN exonuclease activity by isotope dilution mass spectrometry.
Mangerich A; Veith S; Popp O; Fahrer J; Martello R; Bohr VA; Bürkle A
Mech Ageing Dev; 2012 Aug; 133(8):575-9. PubMed ID: 22766507
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]