BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 20516369)

  • 1. Bryostatin 1 inhibits phorbol ester-induced apoptosis in prostate cancer cells by differentially modulating protein kinase C (PKC) delta translocation and preventing PKCdelta-mediated release of tumor necrosis factor-alpha.
    von Burstin VA; Xiao L; Kazanietz MG
    Mol Pharmacol; 2010 Sep; 78(3):325-32. PubMed ID: 20516369
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Some phorbol esters might partially resemble bryostatin 1 in their actions on LNCaP prostate cancer cells and U937 leukemia cells.
    Kedei N; Lubart E; Lewin NE; Telek A; Lim L; Mannan P; Garfield SH; Kraft MB; Keck GE; Kolusheva S; Jelinek R; Blumberg PM
    Chembiochem; 2011 May; 12(8):1242-51. PubMed ID: 21542090
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKCalpha.
    Garcia-Bermejo ML; Leskow FC; Fujii T; Wang Q; Blumberg PM; Ohba M; Kuroki T; Han KC; Lee J; Marquez VE; Kazanietz MG
    J Biol Chem; 2002 Jan; 277(1):645-55. PubMed ID: 11584014
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation.
    Szallasi Z; Denning MF; Smith CB; Dlugosz AA; Yuspa SH; Pettit GR; Blumberg PM
    Mol Pharmacol; 1994 Nov; 46(5):840-50. PubMed ID: 7969070
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bryostatin 1 induces prolonged activation of extracellular regulated protein kinases in and apoptosis of LNCaP human prostate cancer cells overexpressing protein kinase calpha.
    Gschwend JE; Fair WR; Powell CT
    Mol Pharmacol; 2000 Jun; 57(6):1224-34. PubMed ID: 10825394
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta.
    Fujii T; García-Bermejo ML; Bernabó JL; Caamaño J; Ohba M; Kuroki T; Li L; Yuspa SH; Kazanietz MG
    J Biol Chem; 2000 Mar; 275(11):7574-82. PubMed ID: 10713064
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of epithelial transport and barrier function by distinct protein kinase C isoforms.
    Song JC; Hanson CM; Tsai V; Farokhzad OC; Lotz M; Matthews JB
    Am J Physiol Cell Physiol; 2001 Aug; 281(2):C649-61. PubMed ID: 11443064
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The catalytic domain of protein kinase Cdelta confers protection from down-regulation induced by bryostatin 1.
    Lorenzo PS; Bögi K; Acs P; Pettit GR; Blumberg PM
    J Biol Chem; 1997 Dec; 272(52):33338-43. PubMed ID: 9407126
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts.
    Szallasi Z; Smith CB; Pettit GR; Blumberg PM
    J Biol Chem; 1994 Jan; 269(3):2118-24. PubMed ID: 8294465
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhancement of cisplatin sensitivity of cisplatin-resistant human cervical carcinoma cells by bryostatin 1.
    Mohanty S; Huang J; Basu A
    Clin Cancer Res; 2005 Sep; 11(18):6730-7. PubMed ID: 16166454
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overexpression of PKCepsilon sensitizes LNCaP human prostate cancer cells to induction of apoptosis by bryostatin 1.
    Powell CT; Yin L
    Int J Cancer; 2006 Mar; 118(6):1572-6. PubMed ID: 16184549
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phorbol ester-induced apoptosis in prostate cancer cells via autocrine activation of the extrinsic apoptotic cascade: a key role for protein kinase C delta.
    Gonzalez-Guerrico AM; Kazanietz MG
    J Biol Chem; 2005 Nov; 280(47):38982-91. PubMed ID: 16183650
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential effect of bryostatin 1 and phorbol 12-myristate 13-acetate on HOP-92 cell proliferation is mediated by down-regulation of protein kinase Cdelta.
    Choi SH; Hyman T; Blumberg PM
    Cancer Res; 2006 Jul; 66(14):7261-9. PubMed ID: 16849575
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The synthetic bryostatin analog Merle 23 dissects distinct mechanisms of bryostatin activity in the LNCaP human prostate cancer cell line.
    Kedei N; Telek A; Czap A; Lubart ES; Czifra G; Yang D; Chen J; Morrison T; Goldsmith PK; Lim L; Mannan P; Garfield SH; Kraft MB; Li W; Keck GE; Blumberg PM
    Biochem Pharmacol; 2011 Jun; 81(11):1296-308. PubMed ID: 21458422
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phorbol ester-induced apoptosis of C4-2 cells requires both a unique and a redundant protein kinase C signaling pathway.
    Yin L; Bennani-Baiti N; Powell CT
    J Biol Chem; 2005 Feb; 280(7):5533-41. PubMed ID: 15611126
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein kinase C activation without membrane contact in platelets stimulated by bryostatin.
    Grabarek J; Ware JA
    J Biol Chem; 1993 Mar; 268(8):5543-9. PubMed ID: 8449916
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PKC-mediated secretion of death factors in LNCaP prostate cancer cells is regulated by androgens.
    Xiao L; Gonzalez-Guerrico A; Kazanietz MG
    Mol Carcinog; 2009 Mar; 48(3):187-195. PubMed ID: 18756441
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bryostatins selectively regulate protein kinase C-mediated effects on GH4 cell proliferation.
    Mackanos EA; Pettit GR; Ramsdell JS
    J Biol Chem; 1991 Jun; 266(17):11205-12. PubMed ID: 1904062
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activities.
    Chen J; Giridhar KV; Zhang L; Xu S; Wang QJ
    Carcinogenesis; 2011 Aug; 32(8):1198-206. PubMed ID: 21665893
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tumor promotion by depleting cells of protein kinase C delta.
    Lu Z; Hornia A; Jiang YW; Zang Q; Ohno S; Foster DA
    Mol Cell Biol; 1997 Jun; 17(6):3418-28. PubMed ID: 9154841
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.