268 related articles for article (PubMed ID: 20519552)
1. Preclinical and clinical evidence for the collaborative transport and renal secretion of an oxazolidinone antibiotic by organic anion transporter 3 (OAT3/SLC22A8) and multidrug and toxin extrusion protein 1 (MATE1/SLC47A1).
Lai Y; Sampson KE; Balogh LM; Brayman TG; Cox SR; Adams WJ; Kumar V; Stevens JC
J Pharmacol Exp Ther; 2010 Sep; 334(3):936-44. PubMed ID: 20519552
[TBL] [Abstract][Full Text] [Related]
2. A role for the organic anion transporter OAT3 in renal creatinine secretion in mice.
Vallon V; Eraly SA; Rao SR; Gerasimova M; Rose M; Nagle M; Anzai N; Smith T; Sharma K; Nigam SK; Rieg T
Am J Physiol Renal Physiol; 2012 May; 302(10):F1293-9. PubMed ID: 22338083
[TBL] [Abstract][Full Text] [Related]
3. 6β-Hydroxycortisol is an endogenous probe for evaluation of drug-drug interactions involving a multispecific renal organic anion transporter, OAT3/SLC22A8, in healthy subjects.
Imamura Y; Tsuruya Y; Damme K; Heer D; Kumagai Y; Maeda K; Murayama N; Okudaira N; Kurihara A; Izumi T; Sugiyama Y; Kusuhara H
Drug Metab Dispos; 2014 Apr; 42(4):685-94. PubMed ID: 24487120
[TBL] [Abstract][Full Text] [Related]
4. Prediction of clinical drug-drug interactions of veliparib (ABT-888) with human renal transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K).
Kikuchi R; Lao Y; Bow DA; Chiou WJ; Andracki ME; Carr RA; Voorman RL; De Morais SM
J Pharm Sci; 2013 Dec; 102(12):4426-32. PubMed ID: 24122511
[TBL] [Abstract][Full Text] [Related]
5. Renal secretion of hydrochlorothiazide involves organic anion transporter 1/3, organic cation transporter 2, and multidrug and toxin extrusion protein 2-K.
Yin J; Wagner DJ; Prasad B; Isoherranen N; Thummel KE; Wang J
Am J Physiol Renal Physiol; 2019 Oct; 317(4):F805-F814. PubMed ID: 31322418
[TBL] [Abstract][Full Text] [Related]
6. The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine.
Matsushima S; Maeda K; Inoue K; Ohta KY; Yuasa H; Kondo T; Nakayama H; Horita S; Kusuhara H; Sugiyama Y
Drug Metab Dispos; 2009 Mar; 37(3):555-9. PubMed ID: 19074525
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.
Tahara H; Kusuhara H; Maeda K; Koepsell H; Fuse E; Sugiyama Y
Drug Metab Dispos; 2006 May; 34(5):743-7. PubMed ID: 16455804
[TBL] [Abstract][Full Text] [Related]
8. Renal tubular secretion of tanshinol: molecular mechanisms, impact on its systemic exposure, and propensity for dose-related nephrotoxicity and for renal herb-drug interactions.
Jia W; Du F; Liu X; Jiang R; Xu F; Yang J; Li L; Wang F; Olaleye OE; Dong J; Li C
Drug Metab Dispos; 2015 May; 43(5):669-78. PubMed ID: 25710938
[TBL] [Abstract][Full Text] [Related]
9. Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.
Ito S; Kusuhara H; Yokochi M; Toyoshima J; Inoue K; Yuasa H; Sugiyama Y
J Pharmacol Exp Ther; 2012 Feb; 340(2):393-403. PubMed ID: 22072731
[TBL] [Abstract][Full Text] [Related]
10. Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human kidney drug transporters.
Han YH; Busler D; Hong Y; Tian Y; Chen C; Rodrigues AD
Drug Metab Dispos; 2010 Jul; 38(7):1064-71. PubMed ID: 20360303
[TBL] [Abstract][Full Text] [Related]
11. Renal Drug Transporters and Drug Interactions.
Ivanyuk A; Livio F; Biollaz J; Buclin T
Clin Pharmacokinet; 2017 Aug; 56(8):825-892. PubMed ID: 28210973
[TBL] [Abstract][Full Text] [Related]
12. A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters.
Tahara H; Kusuhara H; Endou H; Koepsell H; Imaoka T; Fuse E; Sugiyama Y
J Pharmacol Exp Ther; 2005 Oct; 315(1):337-45. PubMed ID: 16006492
[TBL] [Abstract][Full Text] [Related]
13. Renal uptake of substrates for organic anion transporters Oat1 and Oat3 and organic cation transporters Oct1 and Oct2 is altered in rats with adenine-induced chronic renal failure.
Komazawa H; Yamaguchi H; Hidaka K; Ogura J; Kobayashi M; Iseki K
J Pharm Sci; 2013 Mar; 102(3):1086-94. PubMed ID: 23280877
[TBL] [Abstract][Full Text] [Related]
14. Involvement of Renal Efflux Transporter MATE1 in Renal Excretion of Flecainide.
Doki K; Apáti S; Sakata T; Homma M
Biol Pharm Bull; 2019; 42(7):1226-1229. PubMed ID: 31257298
[TBL] [Abstract][Full Text] [Related]
15. Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells.
Tsuda M; Terada T; Ueba M; Sato T; Masuda S; Katsura T; Inui K
J Pharmacol Exp Ther; 2009 Apr; 329(1):185-91. PubMed ID: 19164462
[TBL] [Abstract][Full Text] [Related]
16. Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
Yamada A; Maeda K; Kamiyama E; Sugiyama D; Kondo T; Shiroyanagi Y; Nakazawa H; Okano T; Adachi M; Schuetz JD; Adachi Y; Hu Z; Kusuhara H; Sugiyama Y
Drug Metab Dispos; 2007 Dec; 35(12):2166-76. PubMed ID: 17823233
[TBL] [Abstract][Full Text] [Related]
17. Renal Excretion of Dabigatran: The Potential Role of Multidrug and Toxin Extrusion (MATE) Proteins.
Shen H; Yao M; Sinz M; Marathe P; Rodrigues AD; Zhu M
Mol Pharm; 2019 Sep; 16(9):4065-4076. PubMed ID: 31335150
[TBL] [Abstract][Full Text] [Related]
18. Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists.
Tahara H; Kusuhara H; Chida M; Fuse E; Sugiyama Y
J Pharmacol Exp Ther; 2006 Mar; 316(3):1187-94. PubMed ID: 16291876
[TBL] [Abstract][Full Text] [Related]
19. Effects of 1α,25-dihydroxyvitamin D3 , the natural vitamin D receptor ligand, on the pharmacokinetics of cefdinir and cefadroxil, organic anion transporter substrates, in rat.
Kim YC; Kim IB; Noh CK; Quach HP; Yoon IS; Chow ECY; Kim M; Jin HE; Cho KH; Chung SJ; Pang KS; Maeng HJ
J Pharm Sci; 2014 Nov; 103(11):3793-3805. PubMed ID: 25266751
[TBL] [Abstract][Full Text] [Related]
20. Blockade of Organic Anion Transport in Humans After Treatment With the Drug Probenecid Leads to Major Metabolic Alterations in Plasma and Urine.
Granados JC; Bhatnagar V; Nigam SK
Clin Pharmacol Ther; 2022 Sep; 112(3):653-664. PubMed ID: 35490380
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
