BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

630 related articles for article (PubMed ID: 20534345)

  • 21. Probing the reaction coordinate of the p300/CBP histone acetyltransferase with bisubstrate analogs.
    Karukurichi KR; Cole PA
    Bioorg Chem; 2011 Feb; 39(1):42-7. PubMed ID: 21111442
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition.
    Dancy BM; Crump NT; Peterson DJ; Mukherjee C; Bowers EM; Ahn YH; Yoshida M; Zhang J; Mahadevan LC; Meyers DJ; Boeke JD; Cole PA
    Chembiochem; 2012 Sep; 13(14):2113-21. PubMed ID: 22961914
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Histone Acetyltransferase p300 Inhibitor Improves Coronary Flow Reserve in SIRT3 (Sirtuin 3) Knockout Mice.
    Su H; Zeng H; He X; Zhu SH; Chen JX
    J Am Heart Assoc; 2020 Sep; 9(18):e017176. PubMed ID: 32865093
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors.
    Lu W; Xiong H; Chen Y; Wang C; Zhang H; Xu P; Han J; Xiao S; Ding H; Chen Z; Lu T; Wang J; Zhang Y; Yue L; Liu YC; Zhang C; Yang Y; Jiang H; Chen K; Zhou B; Luo C
    Bioorg Med Chem; 2018 Nov; 26(20):5397-5407. PubMed ID: 30297119
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Inhibition of different histone acetyltransferases (HATs) uncovers transcription-dependent and -independent acetylation-mediated mechanisms in memory formation.
    Merschbaecher K; Hatko L; Folz J; Mueller U
    Learn Mem; 2016 Feb; 23(2):83-9. PubMed ID: 26773101
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity.
    Shirakawa K; Wang L; Man N; Maksimoska J; Sorum AW; Lim HW; Lee IS; Shimazu T; Newman JC; Schröder S; Ott M; Marmorstein R; Meier J; Nimer S; Verdin E
    Elife; 2016 May; 5():. PubMed ID: 27244239
    [TBL] [Abstract][Full Text] [Related]  

  • 27. E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300.
    Hyndman BD; Thompson P; Bayly R; Côté GP; LeBrun DP
    Biochim Biophys Acta; 2012 May; 1819(5):446-53. PubMed ID: 22387215
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Unravelling novel congeners from acetyllysine mimicking ligand targeting a lysine acetyltransferase PCAF bromodomain.
    Suryanarayanan V; Singh SK
    J Biomol Struct Dyn; 2018 Dec; 36(16):4303-4319. PubMed ID: 29228881
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Histone acetyltransferase inhibitor C646 reverses epithelial to mesenchymal transition of human peritoneal mesothelial cells via blocking TGF-β1/Smad3 signaling pathway in vitro.
    Yang Y; Liu K; Liang Y; Chen Y; Chen Y; Gong Y
    Int J Clin Exp Pathol; 2015; 8(3):2746-54. PubMed ID: 26045780
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Characterization of novel inhibitors of histone acetyltransferases.
    Eliseeva ED; Valkov V; Jung M; Jung MO
    Mol Cancer Ther; 2007 Sep; 6(9):2391-8. PubMed ID: 17876038
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Azide-alkyne cycloaddition affording enzymatically tunable bisubstrate based inhibitors of histone acetyltransferase PCAF.
    van Ameijde J; Zwiebel AP; Ruijtenbeek R; Liskamp RM
    Bioorg Med Chem Lett; 2014 Jan; 24(1):113-6. PubMed ID: 24345448
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Histone deacetylase inhibitors synergize p300 autoacetylation that regulates its transactivation activity and complex formation.
    Stiehl DP; Fath DM; Liang D; Jiang Y; Sang N
    Cancer Res; 2007 Mar; 67(5):2256-2264. PubMed ID: 17332356
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP.
    Zucconi BE; Makofske JL; Meyers DJ; Hwang Y; Wu M; Kuroda MI; Cole PA
    Biochemistry; 2019 Apr; 58(16):2133-2143. PubMed ID: 30924641
    [TBL] [Abstract][Full Text] [Related]  

  • 34. C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe.
    Oike T; Komachi M; Ogiwara H; Amornwichet N; Saitoh Y; Torikai K; Kubo N; Nakano T; Kohno T
    Radiother Oncol; 2014 May; 111(2):222-7. PubMed ID: 24746574
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Acetyltransferase p300 inhibitor reverses hypertension-induced cardiac fibrosis.
    Rai R; Sun T; Ramirez V; Lux E; Eren M; Vaughan DE; Ghosh AK
    J Cell Mol Med; 2019 Apr; 23(4):3026-3031. PubMed ID: 30710427
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Curcumin is an inhibitor of p300 histone acetylatransferase.
    Marcu MG; Jung YJ; Lee S; Chung EJ; Lee MJ; Trepel J; Neckers L
    Med Chem; 2006 Mar; 2(2):169-74. PubMed ID: 16787365
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor.
    Peng J; Ramatchandirin B; Wang Y; Pearah A; Namachivayam K; Wolf RM; Steele K; MohanKumar K; Yu L; Guo S; White MF; Maheshwari A; He L
    J Biol Chem; 2022 Mar; 298(3):101621. PubMed ID: 35074429
    [TBL] [Abstract][Full Text] [Related]  

  • 38. RNA Binding to CBP Stimulates Histone Acetylation and Transcription.
    Bose DA; Donahue G; Reinberg D; Shiekhattar R; Bonasio R; Berger SL
    Cell; 2017 Jan; 168(1-2):135-149.e22. PubMed ID: 28086087
    [TBL] [Abstract][Full Text] [Related]  

  • 39. 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site.
    Ghizzoni M; Wu J; Gao T; Haisma HJ; Dekker FJ; George Zheng Y
    Eur J Med Chem; 2012 Jan; 47(1):337-44. PubMed ID: 22100137
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors.
    Huhn AJ; Gardberg AS; Poy F; Brucelle F; Vivat V; Cantone N; Patel G; Patel C; Cummings R; Sims R; Levell J; Audia JE; Bommi-Reddy A; Wilson JE
    ChemMedChem; 2020 Jun; 15(11):955-960. PubMed ID: 32181984
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 32.