These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 20534554)

  • 1. Organometallic mechanism of action and inhibition of the 4Fe-4S isoprenoid biosynthesis protein GcpE (IspG).
    Wang W; Li J; Wang K; Huang C; Zhang Y; Oldfield E
    Proc Natl Acad Sci U S A; 2010 Jun; 107(25):11189-93. PubMed ID: 20534554
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bioorganometallic mechanism of action, and inhibition, of IspH.
    Wang W; Wang K; Liu YL; No JH; Li J; Nilges MJ; Oldfield E
    Proc Natl Acad Sci U S A; 2010 Mar; 107(10):4522-7. PubMed ID: 20173096
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of the GcpE-HMBPP complex from Thermus thermophilius.
    Rekittke I; Warkentin E; Jomaa H; Ermler U
    Biochem Biophys Res Commun; 2015 Mar; 458(2):246-50. PubMed ID: 25660452
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of the 4Fe-4S Proteins IspG and IspH: an EPR, ENDOR and HYSCORE Investigation.
    Guerra F; Wang K; Li J; Wang W; Liu YL; Amin S; Oldfield E
    Chem Sci; 2014 Apr; 5(4):1642-1649. PubMed ID: 24999381
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of the GcpE (IspG)-MEcPP complex from Thermus thermophilus.
    Rekittke I; Jomaa H; Ermler U
    FEBS Lett; 2012 Sep; 586(19):3452-7. PubMed ID: 22967895
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Paramagnetic intermediates of (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE/IspG) under steady-state and pre-steady-state conditions.
    Xu W; Lees NS; Adedeji D; Wiesner J; Jomaa H; Hoffman BM; Duin EC
    J Am Chem Soc; 2010 Oct; 132(41):14509-20. PubMed ID: 20863107
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Active-Site [4Fe-4S] Cluster in the Isoprenoid Biosynthesis Enzyme IspH Adopts Unexpected Redox States during Ligand Binding and Catalysis.
    Ghebreamlak S; Stoian SA; Lees NS; Cronin B; Smith F; Ross MO; Telser J; Hoffman BM; Duin EC
    J Am Chem Soc; 2024 Feb; 146(6):3926-3942. PubMed ID: 38291562
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Possible direct involvement of the active-site [4Fe-4S] cluster of the GcpE enzyme from Thermus thermophilus in the conversion of MEcPP.
    Adedeji D; Hernandez H; Wiesner J; Köhler U; Jomaa H; Duin EC
    FEBS Lett; 2007 Jan; 581(2):279-83. PubMed ID: 17214985
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Broken-Symmetry DFT Computations for the Reaction Pathway of IspH, an Iron-Sulfur Enzyme in Pathogenic Bacteria.
    Blachly PG; Sandala GM; Giammona DA; Bashford D; McCammon JA; Noodleman L
    Inorg Chem; 2015 Jul; 54(13):6439-61. PubMed ID: 26098647
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isoprenoid biosynthesis in chloroplasts via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE) from Arabidopsis thaliana is a [4Fe-4S] protein.
    Seemann M; Wegner P; Schünemann V; Bui BT; Wolff M; Marquet A; Trautwein AX; Rohmer M
    J Biol Inorg Chem; 2005 Mar; 10(2):131-7. PubMed ID: 15650872
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An ENDOR and HYSCORE investigation of a reaction intermediate in IspG (GcpE) catalysis.
    Wang W; Wang K; Li J; Nellutla S; Smirnova TI; Oldfield E
    J Am Chem Soc; 2011 Jun; 133(22):8400-3. PubMed ID: 21574560
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A closer look at the spectroscopic properties of possible reaction intermediates in wild-type and mutant (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase.
    Xu W; Lees NS; Hall D; Welideniya D; Hoffman BM; Duin EC
    Biochemistry; 2012 Jun; 51(24):4835-49. PubMed ID: 22646150
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE).
    Quitterer F; Frank A; Wang K; Rao G; O'Dowd B; Li J; Guerra F; Abdel-Azeim S; Bacher A; Eppinger J; Oldfield E; Groll M
    J Mol Biol; 2015 Jun; 427(12):2220-8. PubMed ID: 25868383
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Isoprenoid biosynthesis in plant chloroplasts via the MEP pathway: direct thylakoid/ferredoxin-dependent photoreduction of GcpE/IspG.
    Seemann M; Tse Sum Bui B; Wolff M; Miginiac-Maslow M; Rohmer M
    FEBS Lett; 2006 Mar; 580(6):1547-52. PubMed ID: 16480720
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Electron-nuclear double resonance spectroscopic evidence that S-adenosylmethionine binds in contact with the catalytically active [4Fe-4S](+) cluster of pyruvate formate-lyase activating enzyme.
    Walsby CJ; Hong W; Broderick WE; Cheek J; Ortillo D; Broderick JB; Hoffman BM
    J Am Chem Soc; 2002 Mar; 124(12):3143-51. PubMed ID: 11902903
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of the E-1-hydroxy-2-methyl-but-2-enyl-4-diphosphate synthase (GcpE) from Thermus thermophilus.
    Rekittke I; Nonaka T; Wiesner J; Demmer U; Warkentin E; Jomaa H; Ermler U
    FEBS Lett; 2011 Feb; 585(3):447-51. PubMed ID: 21167158
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isoprenoid biosynthesis through the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE) is a [4Fe-4S] protein.
    Seemann M; Bui BT; Wolff M; Tritsch D; Campos N; Boronat A; Marquet A; Rohmer M
    Angew Chem Int Ed Engl; 2002 Nov; 41(22):4337-9. PubMed ID: 12434382
    [No Abstract]   [Full Text] [Related]  

  • 18. Cyanobacterial non-mevalonate pathway: (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase interacts with ferredoxin in Thermosynechococcus elongatus BP-1.
    Okada K; Hase T
    J Biol Chem; 2005 May; 280(21):20672-9. PubMed ID: 15792953
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of the Fe(4)S(4)-cluster-containing protein IspH (LytB): electron paramagnetic resonance, metallacycles, and mechanisms.
    Wang K; Wang W; No JH; Zhang Y; Zhang Y; Oldfield E
    J Am Chem Soc; 2010 May; 132(19):6719-27. PubMed ID: 20426416
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Irreversible Inhibition of IspG, a Target for the Development of New Antimicrobials, by a 2-Vinyl Analogue of its MEcPP Substrate.
    Herrscher V; Witjaksono C; Buchotte M; Ferret C; Massicot F; Vasse JL; Borel F; Behr JB; Seemann M
    Chemistry; 2022 May; 28(30):e202200241. PubMed ID: 35285984
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.