BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 20538005)

  • 1. K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies.
    Garforth SJ; Domaoal RA; Lwatula C; Landau MJ; Meyer AJ; Anderson KS; Prasad VR
    J Mol Biol; 2010 Aug; 401(1):33-44. PubMed ID: 20538005
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lys66 residue as a determinant of high mismatch extension and misinsertion rates of HIV-1 reverse transcriptase.
    Lwatula C; Garforth SJ; Prasad VR
    FEBS J; 2012 Nov; 279(21):4010-24. PubMed ID: 22925131
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutational analysis of Lys65 of HIV-1 reverse transcriptase.
    Sluis-Cremer N; Arion D; Kaushik N; Lim H; Parniak MA
    Biochem J; 2000 May; 348 Pt 1(Pt 1):77-82. PubMed ID: 10794716
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection.
    Garforth SJ; Kim TW; Parniak MA; Kool ET; Prasad VR
    J Mol Biol; 2007 Jan; 365(1):38-49. PubMed ID: 17055529
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis.
    Weiss KK; Chen R; Skasko M; Reynolds HM; Lee K; Bambara RA; Mansky LM; Kim B
    Biochemistry; 2004 Apr; 43(15):4490-500. PubMed ID: 15078095
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Studies on the effects of truncating alpha-helix E' of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis.
    Menéndez-Arias L
    Biochemistry; 1998 Nov; 37(47):16636-44. PubMed ID: 9843431
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanistic insights into the role of Val75 of HIV-1 reverse transcriptase in misinsertion and mispair extension fidelity of DNA synthesis.
    Matamoros T; Kim B; Menéndez-Arias L
    J Mol Biol; 2008 Feb; 375(5):1234-48. PubMed ID: 18155043
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanistic differences in RNA-dependent DNA polymerization and fidelity between murine leukemia virus and HIV-1 reverse transcriptases.
    Skasko M; Weiss KK; Reynolds HM; Jamburuthugoda V; Lee K; Kim B
    J Biol Chem; 2005 Apr; 280(13):12190-200. PubMed ID: 15644314
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nucleotide specificity of HIV-1 reverse transcriptases with amino acid substitutions affecting Ala-114.
    Cases-González CE; Menéndez-Arias L
    Biochem J; 2005 Apr; 387(Pt 1):221-9. PubMed ID: 15548134
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase.
    Harris D; Kaushik N; Pandey PK; Yadav PN; Pandey VN
    J Biol Chem; 1998 Dec; 273(50):33624-34. PubMed ID: 9837947
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p53 enhances the fidelity of DNA synthesis by human immunodeficiency virus type 1 reverse transcriptase.
    Bakhanashvili M
    Oncogene; 2001 Nov; 20(52):7635-44. PubMed ID: 11753641
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of polymerase activity due to Tyr to Phe substitution in the YMDD motif of human immunodeficiency virus type-1 reverse transcriptase is compensated by Met to Val substitution within the same motif.
    Harris D; Yadav PN; Pandey VN
    Biochemistry; 1998 Jul; 37(27):9630-40. PubMed ID: 9657675
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis.
    Pandey VN; Kaushik N; Rege N; Sarafianos SG; Yadav PN; Modak MJ
    Biochemistry; 1996 Feb; 35(7):2168-79. PubMed ID: 8652558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Steady-state and pre-steady-state kinetic analysis of 8-oxo-7,8-dihydroguanosine triphosphate incorporation and extension by replicative and repair DNA polymerases.
    Einolf HJ; Schnetz-Boutaud N; Guengerich FP
    Biochemistry; 1998 Sep; 37(38):13300-12. PubMed ID: 9748338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The fidelity of misinsertion and mispair extension throughout DNA synthesis exhibited by mutants of the reverse transcriptase of human immunodeficiency virus type 2 resistant to nucleoside analogs.
    Taube R; Avidan O; Hizi A
    Eur J Biochem; 1997 Nov; 250(1):106-14. PubMed ID: 9431997
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impact of template overhang-binding region of HIV-1 RT on the binding and orientation of the duplex region of the template-primer.
    Upadhyay AK; Talele TT; Pandey VN
    Mol Cell Biochem; 2010 May; 338(1-2):19-33. PubMed ID: 19921401
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase.
    Zinnen S; Hsieh JC; Modrich P
    J Biol Chem; 1994 Sep; 269(39):24195-202. PubMed ID: 7523369
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The fidelity of 3' misinsertion and mispair extension during DNA synthesis exhibited by two drug-resistant mutants of the reverse transcriptase of human immunodeficiency virus type 1 with Leu74-->Val and Glu89-->Gly.
    Rubinek T; Bakhanashvili M; Taube R; Avidan O; Hizi A
    Eur J Biochem; 1997 Jul; 247(1):238-47. PubMed ID: 9249032
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity.
    Kim B; Ayran JC; Sagar SG; Adman ET; Fuller SM; Tran NH; Horrigan J
    J Biol Chem; 1999 Sep; 274(39):27666-73. PubMed ID: 10488107
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interactions between HIV-1 reverse transcriptase and the downstream template strand in stable complexes with primer-template.
    Rutvisuttinunt W; Meyer PR; Scott WA
    PLoS One; 2008; 3(10):e3561. PubMed ID: 18974785
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.