BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 20540746)

  • 1. Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling.
    Liu YY; Gupta V; Patwardhan GA; Bhinge K; Zhao Y; Bao J; Mehendale H; Cabot MC; Li YT; Jazwinski SM
    Mol Cancer; 2010 Jun; 9():145. PubMed ID: 20540746
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis.
    Patwardhan GA; Zhang QJ; Yin D; Gupta V; Bao J; Senkal CE; Ogretmen B; Cabot MC; Shah GV; Sylvester PW; Jazwinski SM; Liu YY
    PLoS One; 2009 Sep; 4(9):e6938. PubMed ID: 19742320
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells.
    Tyler A; Johansson A; Karlsson T; Gudey SK; Brännström T; Grankvist K; Behnam-Motlagh P
    Exp Cell Res; 2015 Aug; 336(1):23-32. PubMed ID: 26004871
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance.
    Liu YY; Han TY; Giuliano AE; Hansen N; Cabot MC
    J Biol Chem; 2000 Mar; 275(10):7138-43. PubMed ID: 10702281
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mixed backbone antisense glucosylceramide synthase oligonucleotide (MBO-asGCS) loaded solid lipid nanoparticles: in vitro characterization and reversal of multidrug resistance in NCI/ADR-RES cells.
    Siddiqui A; Patwardhan GA; Liu YY; Nazzal S
    Int J Pharm; 2010 Nov; 400(1-2):251-9. PubMed ID: 20816930
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Co-suppression of MDR1 (multidrug resistance 1) and GCS (glucosylceramide synthase) restores sensitivity to multidrug resistance breast cancer cells by RNA interference (RNAi).
    Zhang X; Li J; Qiu Z; Gao P; Wu X; Zhou G
    Cancer Biol Ther; 2009 Jun; 8(12):1117-21. PubMed ID: 19502811
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The effect of glucosylceramide synthase on P-glycoprotein function in K562/AO2 leukemia drug-resistance cell line.
    Zhang YY; Xie KM; Yang GQ; Mu HJ; Yin Y; Zhang B; Xie P
    Int J Hematol; 2011 Mar; 93(3):361-367. PubMed ID: 21380926
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells.
    Liu YY; Han TY; Yu JY; Bitterman A; Le A; Giuliano AE; Cabot MC
    J Lipid Res; 2004 May; 45(5):933-40. PubMed ID: 14967819
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gb3-cSrc complex in glycosphingolipid-enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β-catenin-activated RNA methylation.
    Roy KR; Uddin MB; Roy SC; Hill RA; Marshall J; Li YT; Chamcheu JC; Lu H; Liu YY
    FASEB Bioadv; 2020 Nov; 2(11):653-667. PubMed ID: 33205006
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance.
    Liu YY; Hill RA; Li YT
    Adv Cancer Res; 2013; 117():59-89. PubMed ID: 23290777
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog.
    De Rosa MF; Ackerley C; Wang B; Ito S; Clarke DM; Lingwood C
    J Biol Chem; 2008 Feb; 283(8):4501-11. PubMed ID: 18003606
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Forced expression of heat shock protein 27 (Hsp27) reverses P-glycoprotein (ABCB1)-mediated drug efflux and MDR1 gene expression in Adriamycin-resistant human breast cancer cells.
    Kanagasabai R; Krishnamurthy K; Druhan LJ; Ilangovan G
    J Biol Chem; 2011 Sep; 286(38):33289-300. PubMed ID: 21784846
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metformin inhibits P-glycoprotein expression via the NF-κB pathway and CRE transcriptional activity through AMPK activation.
    Kim HG; Hien TT; Han EH; Hwang YP; Choi JH; Kang KW; Kwon KI; Kim BH; Kim SK; Song GY; Jeong TC; Jeong HG
    Br J Pharmacol; 2011 Mar; 162(5):1096-108. PubMed ID: 21054339
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Survivin transcription is associated with P-glycoprotein/MDR1 overexpression in the multidrug resistance of MCF-7 breast cancer cells.
    Liu F; Liu S; He S; Xie Z; Zu X; Jiang Y
    Oncol Rep; 2010 May; 23(5):1469-75. PubMed ID: 20372866
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Knockdown of the Wnt receptor Frizzled-1 (FZD1) reduces MDR1/P-glycoprotein expression in multidrug resistant leukemic cells and inhibits leukemic cell proliferation.
    Wang YH; Imai Y; Shiseki M; Tanaka J; Motoji T
    Leuk Res; 2018 Apr; 67():99-108. PubMed ID: 29482174
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ceramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells.
    Gupta V; Bhinge KN; Hosain SB; Xiong K; Gu X; Shi R; Ho MY; Khoo KH; Li SC; Li YT; Ambudkar SV; Jazwinski SM; Liu YY
    J Biol Chem; 2012 Oct; 287(44):37195-205. PubMed ID: 22936806
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs.
    Gouazé V; Liu YY; Prickett CS; Yu JY; Giuliano AE; Cabot MC
    Cancer Res; 2005 May; 65(9):3861-7. PubMed ID: 15867385
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ceramide and glucosylceramide upregulate expression of the multidrug resistance gene MDR1 in cancer cells.
    Gouazé-Andersson V; Yu JY; Kreitenberg AJ; Bielawska A; Giuliano AE; Cabot MC
    Biochim Biophys Acta; 2007 Dec; 1771(12):1407-17. PubMed ID: 18035065
    [TBL] [Abstract][Full Text] [Related]  

  • 19. UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells.
    Wegner MS; Schömel N; Gruber L; Örtel SB; Kjellberg MA; Mattjus P; Kurz J; Trautmann S; Peng B; Wegner M; Kaulich M; Ahrends R; Geisslinger G; Grösch S
    Cell Mol Life Sci; 2018 Sep; 75(18):3393-3410. PubMed ID: 29549423
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CBP-dependent Wnt/β-catenin signaling is crucial in regulation of MDR1 transcription.
    Xia Z; Guo M; Liu H; Jiang L; Li Q; Peng J; Li JD; Shan B; Feng P; Ma H
    Curr Cancer Drug Targets; 2015; 15(6):519-32. PubMed ID: 25968898
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.