These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 20541935)

  • 1. 4-Substituted-7-N-alkyl-N-acetyl 2-aminobenzothiazole amides: drug-like and non-xanthine based A2B adenosine receptor antagonists.
    Cheung AW; Brinkman J; Firooznia F; Flohr A; Grimsby J; Gubler ML; Guertin K; Hamid R; Marcopulos N; Norcross RD; Qi L; Ramsey G; Tan J; Wen Y; Sarabu R
    Bioorg Med Chem Lett; 2010 Jul; 20(14):4140-6. PubMed ID: 20541935
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of benzothiazole-based adenosine A2B receptor antagonists with improved A2A selectivity.
    Firooznia F; Cheung AW; Brinkman J; Grimsby J; Gubler ML; Hamid R; Marcopulos N; Ramsey G; Tan J; Wen Y; Sarabu R
    Bioorg Med Chem Lett; 2011 Apr; 21(7):1933-6. PubMed ID: 21388809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.
    Baraldi PG; Tabrizi MA; Preti D; Bovero A; Romagnoli R; Fruttarolo F; Zaid NA; Moorman AR; Varani K; Gessi S; Merighi S; Borea PA
    J Med Chem; 2004 Mar; 47(6):1434-47. PubMed ID: 14998332
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of novel quinolinone adenosine A2B antagonists.
    McGuinness BF; Ho KK; Stauffer TM; Rokosz LL; Mannava N; Kultgen SG; Saionz K; Klon A; Chen W; Desai H; Rogers WL; Webb M; Yin J; Jiang Y; Li T; Yan H; Jing K; Zhang S; Majumdar KK; Srivastava V; Saha S
    Bioorg Med Chem Lett; 2010 Dec; 20(24):7414-20. PubMed ID: 21055932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists.
    Baraldi PG; Baraldi S; Saponaro G; Preti D; Romagnoli R; Piccagli L; Cavalli A; Recanatini M; Moorman AR; Zaid AN; Varani K; Borea PA; Tabrizi MA
    J Med Chem; 2012 Jan; 55(2):797-811. PubMed ID: 22148859
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of novel xanthine derivatives as potent and selective A
    Basu S; Barawkar DA; Ramdas V; Patel M; Waman Y; Panmand A; Kumar S; Thorat S; Naykodi M; Goswami A; Reddy BS; Prasad V; Chaturvedi S; Quraishi A; Menon S; Paliwal S; Kulkarni A; Karande V; Ghosh I; Mustafa S; De S; Jain V; Banerjee ER; Rouduri SR; Palle VP; Chugh A; Mookhtiar KA
    Eur J Med Chem; 2017 Jul; 134():218-229. PubMed ID: 28415011
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A
    Basu S; Barawkar DA; Ramdas V; Waman Y; Patel M; Panmand A; Kumar S; Thorat S; Bonagiri R; Jadhav D; Mukhopadhyay P; Prasad V; Reddy BS; Goswami A; Chaturvedi S; Menon S; Quraishi A; Ghosh I; Dusange S; Paliwal S; Kulkarni A; Karande V; Thakre R; Bedse G; Rouduri S; Gundu J; Palle VP; Chugh A; Mookhtiar KA
    Eur J Med Chem; 2017 Feb; 127():986-996. PubMed ID: 27842891
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists.
    Tabrizi MA; Baraldi PG; Preti D; Romagnoli R; Saponaro G; Baraldi S; Moorman AR; Zaid AN; Varani K; Borea PA
    Bioorg Med Chem; 2008 Mar; 16(5):2419-30. PubMed ID: 18077171
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A(2B) adenosine receptor antagonists.
    Eastwood P; Gonzalez J; Paredes S; Nueda A; Domenech T; Alberti J; Vidal B
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1697-700. PubMed ID: 20137946
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.
    Kalla RV; Elzein E; Perry T; Li X; Palle V; Varkhedkar V; Gimbel A; Maa T; Zeng D; Zablocki J
    J Med Chem; 2006 Jun; 49(12):3682-92. PubMed ID: 16759111
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1,3-dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships.
    Fernández F; Caamaño O; Isabel Nieto M; López C; García-Mera X; Stefanachi A; Nicolotti O; Isabel Loza M; Brea J; Esteve C; Segarra V; Vidal B; Carotti A
    Bioorg Med Chem; 2009 May; 17(10):3618-29. PubMed ID: 19398343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An efficient route to xanthine based A(2A) adenosine receptor antagonists and functional derivatives.
    Labeaume P; Dong M; Sitkovsky M; Jones EV; Thomas R; Sadler S; Kallmerten AE; Jones GB
    Org Biomol Chem; 2010 Sep; 8(18):4155-7. PubMed ID: 20652178
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor.
    Stefanachi A; Brea JM; Cadavid MI; Centeno NB; Esteve C; Loza MI; Martinez A; Nieto R; Raviña E; Sanz F; Segarra V; Sotelo E; Vidal B; Carotti A
    Bioorg Med Chem; 2008 Mar; 16(6):2852-69. PubMed ID: 18226909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel 1,3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists.
    Elzein E; Kalla R; Li X; Perry T; Parkhill E; Palle V; Varkhedkar V; Gimbel A; Zeng D; Lustig D; Leung K; Zablocki J
    Bioorg Med Chem Lett; 2006 Jan; 16(2):302-6. PubMed ID: 16275090
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-affinity relationships of adenosine A2B receptor ligands.
    Beukers MW; Meurs I; Ijzerman AP
    Med Res Rev; 2006 Sep; 26(5):667-98. PubMed ID: 16847822
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of Potent and Highly Selective A2B Adenosine Receptor Antagonist Chemotypes.
    El Maatougui A; Azuaje J; González-Gómez M; Miguez G; Crespo A; Carbajales C; Escalante L; García-Mera X; Gutiérrez-de-Terán H; Sotelo E
    J Med Chem; 2016 Mar; 59(5):1967-83. PubMed ID: 26824742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A₂B adenosine receptor antagonists.
    Taliani S; Pugliesi I; Barresi E; Simorini F; Salerno S; La Motta C; Marini AM; Cosimelli B; Cosconati S; Di Maro S; Marinelli L; Daniele S; Trincavelli ML; Greco G; Novellino E; Martini C; Da Settimo F
    J Med Chem; 2012 Feb; 55(4):1490-9. PubMed ID: 22257095
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new orally bioavailable dual adenosine A2B/A3 receptor antagonist with therapeutic potential.
    Press NJ; Taylor RJ; Fullerton JD; Tranter P; McCarthy C; Keller TH; Brown L; Cheung R; Christie J; Haberthuer S; Hatto JD; Keenan M; Mercer MK; Press NE; Sahri H; Tuffnell AR; Tweed M; Fozard JR
    Bioorg Med Chem Lett; 2005 Jun; 15(12):3081-5. PubMed ID: 15876531
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists.
    Rodríguez-Borges JE; García-Mera X; Balo MC; Brea J; Caamaño O; Fernández F; López C; Loza MI; Nieto MI
    Bioorg Med Chem; 2010 Mar; 18(5):2001-9. PubMed ID: 20137957
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.
    Borrmann T; Hinz S; Bertarelli DC; Li W; Florin NC; Scheiff AB; Müller CE
    J Med Chem; 2009 Jul; 52(13):3994-4006. PubMed ID: 19569717
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.