BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 20541935)

  • 21. 1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships.
    Stefanachi A; Nicolotti O; Leonetti F; Cellamare S; Campagna F; Loza MI; Brea JM; Mazza F; Gavuzzo E; Carotti A
    Bioorg Med Chem; 2008 Nov; 16(22):9780-9. PubMed ID: 18938084
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor.
    Carotti A; Cadavid MI; Centeno NB; Esteve C; Loza MI; Martinez A; Nieto R; Raviña E; Sanz F; Segarra V; Sotelo E; Stefanachi A; Vidal B
    J Med Chem; 2006 Jan; 49(1):282-99. PubMed ID: 16392813
    [TBL] [Abstract][Full Text] [Related]  

  • 23. 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands.
    Lambertucci C; Antonini I; Buccioni M; Dal Ben D; Kachare DD; Volpini R; Klotz KN; Cristalli G
    Bioorg Med Chem; 2009 Apr; 17(7):2812-22. PubMed ID: 19282184
    [TBL] [Abstract][Full Text] [Related]  

  • 24. 8-Substituted-9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B.
    Carotti A; Stefanachi A; Raviña E; Sotelo E; Loza MI; Cadavid MI; Centeno NB; Nicolotti O
    Eur J Med Chem; 2004 Oct; 39(10):879-87. PubMed ID: 15464622
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and biological activity of new potential agonists for the human adenosine A2A receptor.
    Bosch MP; Campos F; Niubó I; Rosell G; Díaz JL; Brea J; Loza MI; Guerrero A
    J Med Chem; 2004 Jul; 47(16):4041-53. PubMed ID: 15267242
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Discovery of a novel A2B adenosine receptor antagonist as a clinical candidate for chronic inflammatory airway diseases.
    Elzein E; Kalla RV; Li X; Perry T; Gimbel A; Zeng D; Lustig D; Leung K; Zablocki J
    J Med Chem; 2008 Apr; 51(7):2267-78. PubMed ID: 18321039
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The discovery of a selective, high affinity A(2B) adenosine receptor antagonist for the potential treatment of asthma.
    Zablocki J; Kalla R; Perry T; Palle V; Varkhedkar V; Xiao D; Piscopio A; Maa T; Gimbel A; Hao J; Chu N; Leung K; Zeng D
    Bioorg Med Chem Lett; 2005 Feb; 15(3):609-12. PubMed ID: 15664822
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis of novel 1-alkyl-8-substituted-3-(3-methoxypropyl) xanthines as putative A(2B) receptor antagonists.
    Nieto MI; Balo MC; Brea J; Caamaño O; Cadavid MI; Fernández F; Mera XG; López C; Rodríguez-Borges JE
    Bioorg Med Chem; 2009 May; 17(9):3426-32. PubMed ID: 19346133
    [TBL] [Abstract][Full Text] [Related]  

  • 29. GPCR structure and activation: an essential role for the first extracellular loop in activating the adenosine A2B receptor.
    Peeters MC; van Westen GJ; Guo D; Wisse LE; Müller CE; Beukers MW; Ijzerman AP
    FASEB J; 2011 Feb; 25(2):632-43. PubMed ID: 21030693
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.
    Pastorin G; Da Ros T; Spalluto G; Deflorian F; Moro S; Cacciari B; Baraldi PG; Gessi S; Varani K; Borea PA
    J Med Chem; 2003 Sep; 46(20):4287-96. PubMed ID: 13678407
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Recent developments in A2B adenosine receptor ligands.
    Kalla RV; Zablocki J; Tabrizi MA; Baraldi PG
    Handb Exp Pharmacol; 2009; (193):99-122. PubMed ID: 19639280
    [TBL] [Abstract][Full Text] [Related]  

  • 32. N(6)-[(hetero)aryl/(cyclo)alkyl-carbamoyl-methoxy-phenyl]-(2-chloro)-5'-N-ethylcarboxamido-adenosines: the first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor.
    Baraldi PG; Preti D; Tabrizi MA; Fruttarolo F; Saponaro G; Baraldi S; Romagnoli R; Moorman AR; Gessi S; Varani K; Borea PA
    Bioorg Med Chem; 2007 Apr; 15(7):2514-27. PubMed ID: 17306548
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Novel non-xanthine antagonist of the A
    Härter M; Kalthof B; Delbeck M; Lustig K; Gerisch M; Schulz S; Kast R; Meibom D; Lindner N
    Eur J Med Chem; 2019 Feb; 163():763-778. PubMed ID: 30576906
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Development of spin-labeled probes for adenosine receptors.
    Ilas J; Pecar S; Hockemeyer J; Euler H; Kirfel A; Müller CE
    J Med Chem; 2005 Mar; 48(6):2108-14. PubMed ID: 15771453
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.
    Balo MC; Brea J; Caamaño O; Fernández F; García-Mera X; López C; Loza MI; Nieto MI; Rodríguez-Borges JE
    Bioorg Med Chem; 2009 Sep; 17(18):6755-60. PubMed ID: 19682912
    [TBL] [Abstract][Full Text] [Related]  

  • 36. New, non-adenosine, high-potency agonists for the human adenosine A2B receptor with an improved selectivity profile compared to the reference agonist N-ethylcarboxamidoadenosine.
    Beukers MW; Chang LC; von Frijtag Drabbe Künzel JK; Mulder-Krieger T; Spanjersberg RF; Brussee J; IJzerman AP
    J Med Chem; 2004 Jul; 47(15):3707-9. PubMed ID: 15239649
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Exploring the structural determinants of novel xanthine derivatives as A
    Yang Y; Li Y; Zhou W; Chen Y; Wu Q; Pan Y; Zhang S; Yang L
    J Biomol Struct Dyn; 2019 Aug; 37(13):3467-3481. PubMed ID: 30175951
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists.
    Yan L; Bertarelli DC; Hayallah AM; Meyer H; Klotz KN; Müller CE
    J Med Chem; 2006 Jul; 49(14):4384-91. PubMed ID: 16821798
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Expression, pharmacological profile, and functional coupling of A2B receptors in a recombinant system and in peripheral blood cells using a novel selective antagonist radioligand, [3H]MRE 2029-F20.
    Gessi S; Varani K; Merighi S; Cattabriga E; Pancaldi C; Szabadkai Y; Rizzuto R; Klotz KN; Leung E; Mac Lennan S; Baraldi PG; Borea PA
    Mol Pharmacol; 2005 Jun; 67(6):2137-47. PubMed ID: 15788741
    [TBL] [Abstract][Full Text] [Related]  

  • 40. [3H]-MRE 2029-F20, a selective antagonist radioligand for the human A2B adenosine receptors.
    Baraldi PG; Tabrizi MA; Preti D; Bovero A; Fruttarolo F; Romagnoli R; Moorman AR; Gessi S; Merighi S; Varani K; Borea PA
    Bioorg Med Chem Lett; 2004 Jul; 14(13):3607-10. PubMed ID: 15177484
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.