These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 20542142)

  • 1. Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase.
    Nakabeppu Y; Oka S; Sheng Z; Tsuchimoto D; Sakumi K
    Mutat Res; 2010 Nov; 703(1):51-8. PubMed ID: 20542142
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MTH1 as a nucleotide pool sanitizing enzyme: Friend or foe?
    Nakabeppu Y; Ohta E; Abolhassani N
    Free Radic Biol Med; 2017 Jun; 107():151-158. PubMed ID: 27833032
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [MTH1, an oxidized purine nucleoside triphosphatase suppresses mitochondrial dysfunction and cell death caused by oxidative stress].
    Nakabeppu Y
    Tanpakushitsu Kakusan Koso; 2005 Jul; 50(8):940-8. PubMed ID: 16001799
    [No Abstract]   [Full Text] [Related]  

  • 4. An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress.
    Yoshimura D; Sakumi K; Ohno M; Sakai Y; Furuichi M; Iwai S; Nakabeppu Y
    J Biol Chem; 2003 Sep; 278(39):37965-73. PubMed ID: 12857738
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides.
    Nakabeppu Y; Kajitani K; Sakamoto K; Yamaguchi H; Tsuchimoto D
    DNA Repair (Amst); 2006 Jul; 5(7):761-72. PubMed ID: 16621731
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Association of MTH1 expression with the tumor malignant potential and poor prognosis in patients with resected lung cancer.
    Fujishita T; Okamoto T; Akamine T; Takamori S; Takada K; Katsura M; Toyokawa G; Shoji F; Shimokawa M; Oda Y; Nakabeppu Y; Maehara Y
    Lung Cancer; 2017 Jul; 109():52-57. PubMed ID: 28577950
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1.
    Sakai Y; Furuichi M; Takahashi M; Mishima M; Iwai S; Shirakawa M; Nakabeppu Y
    J Biol Chem; 2002 Mar; 277(10):8579-87. PubMed ID: 11756418
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxidative damage in nucleic acids and Parkinson's disease.
    Nakabeppu Y; Tsuchimoto D; Yamaguchi H; Sakumi K
    J Neurosci Res; 2007 Apr; 85(5):919-34. PubMed ID: 17279544
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Yamaguchi H; Kajitani K; Dan Y; Furuichi M; Ohno M; Sakumi K; Kang D; Nakabeppu Y
    Cell Death Differ; 2006 Apr; 13(4):551-63. PubMed ID: 16273081
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recognition of nucleotide analogs containing the 7,8-dihydro-8-oxo structure by the human MTH1 protein.
    Kamiya H; Cadena-Amaro C; Dugué L; Yakushiji H; Minakawa N; Matsuda A; Pochet S; Nakabeppu Y; Harashima H
    J Biochem; 2006 Dec; 140(6):843-9. PubMed ID: 17071637
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates.
    Mishima M; Sakai Y; Itoh N; Kamiya H; Furuichi M; Takahashi M; Yamagata Y; Iwai S; Nakabeppu Y; Shirakawa M
    J Biol Chem; 2004 Aug; 279(32):33806-15. PubMed ID: 15133035
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oxidized purine nucleotides, genome instability and neurodegeneration.
    Ventura I; Russo MT; De Luca G; Bignami M
    Mutat Res; 2010 Nov; 703(1):59-65. PubMed ID: 20601098
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mammalian enzymes for preventing transcriptional errors caused by oxidative damage.
    Ishibashi T; Hayakawa H; Ito R; Miyazawa M; Yamagata Y; Sekiguchi M
    Nucleic Acids Res; 2005; 33(12):3779-84. PubMed ID: 16002790
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel Nudix hydrolase for oxidized purine nucleoside triphosphates encoded by ORFYLR151c (PCD1 gene) in Saccharomyces cerevisiae.
    Nunoshiba T; Ishida R; Sasaki M; Iwai S; Nakabeppu Y; Yamamoto K
    Nucleic Acids Res; 2004; 32(18):5339-48. PubMed ID: 15475388
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase activity of human and mouse MTH1 proteins does not depend on the proliferation rate.
    Bialkowski K; Kasprzak KS
    Free Radic Biol Med; 2004 Nov; 37(10):1534-41. PubMed ID: 15477005
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MutT homolog-1 attenuates oxidative DNA damage and delays photoreceptor cell death in inherited retinal degeneration.
    Murakami Y; Ikeda Y; Yoshida N; Notomi S; Hisatomi T; Oka S; De Luca G; Yonemitsu Y; Bignami M; Nakabeppu Y; Ishibashi T
    Am J Pathol; 2012 Oct; 181(4):1378-86. PubMed ID: 22841817
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides.
    Ishibashi T; Hayakawa H; Sekiguchi M
    EMBO Rep; 2003 May; 4(5):479-83. PubMed ID: 12717453
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2.
    Carter M; Jemth AS; Hagenkort A; Page BD; Gustafsson R; Griese JJ; Gad H; Valerie NC; Desroses M; Boström J; Warpman Berglund U; Helleday T; Stenmark P
    Nat Commun; 2015 Aug; 6():7871. PubMed ID: 26238318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage.
    Nakabeppu Y
    Prog Nucleic Acid Res Mol Biol; 2001; 68():75-94. PubMed ID: 11554314
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular genetics and structural biology of human MutT homolog, MTH1.
    Nakabeppu Y
    Mutat Res; 2001 Jun; 477(1-2):59-70. PubMed ID: 11376687
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.