These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 20543968)

  • 1. Small-molecule modulators of inward rectifier K+ channels: recent advances and future possibilities.
    Bhave G; Lonergan D; Chauder BA; Denton JS
    Future Med Chem; 2010 May; 2(5):757-74. PubMed ID: 20543968
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cardiac and renal inward rectifier potassium channel pharmacology: emerging tools for integrative physiology and therapeutics.
    Swale DR; Kharade SV; Denton JS
    Curr Opin Pharmacol; 2014 Apr; 15():7-15. PubMed ID: 24721648
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Screening Technologies for Inward Rectifier Potassium Channels: Discovery of New Blockers and Activators.
    Walsh KB
    SLAS Discov; 2020 Jun; 25(5):420-433. PubMed ID: 32292089
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High-throughput screening for small-molecule modulators of inward rectifier potassium channels.
    Raphemot R; Weaver CD; Denton JS
    J Vis Exp; 2013 Jan; (71):. PubMed ID: 23381507
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Next-generation inward rectifier potassium channel modulators: discovery and molecular pharmacology.
    Weaver CD; Denton JS
    Am J Physiol Cell Physiol; 2021 Jun; 320(6):C1125-C1140. PubMed ID: 33826405
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective inhibition of the K(ir)2 family of inward rectifier potassium channels by a small molecule probe: the discovery, SAR, and pharmacological characterization of ML133.
    Wang HR; Wu M; Yu H; Long S; Stevens A; Engers DW; Sackin H; Daniels JS; Dawson ES; Hopkins CR; Lindsley CW; Li M; McManus OB
    ACS Chem Biol; 2011 Aug; 6(8):845-56. PubMed ID: 21615117
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992.
    Kharade SV; Kurata H; Bender AM; Blobaum AL; Figueroa EE; Duran A; Kramer M; Days E; Vinson P; Flores D; Satlin LM; Meiler J; Weaver CD; Lindsley CW; Hopkins CR; Denton JS
    Mol Pharmacol; 2018 Aug; 94(2):926-937. PubMed ID: 29895592
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of cardiac inward rectifier currents by cationic amphiphilic drugs.
    van der Heyden MA; Stary-Weinzinger A; Sanchez-Chapula JA
    Curr Mol Med; 2013 Sep; 13(8):1284-98. PubMed ID: 23448372
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels.
    Swale DR; Kurata H; Kharade SV; Sheehan J; Raphemot R; Voigtritter KR; Figueroa EE; Meiler J; Blobaum AL; Lindsley CW; Hopkins CR; Denton JS
    ACS Chem Neurosci; 2016 Jul; 7(7):1013-23. PubMed ID: 27184474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1.
    Lewis LM; Bhave G; Chauder BA; Banerjee S; Lornsen KA; Redha R; Fallen K; Lindsley CW; Weaver CD; Denton JS
    Mol Pharmacol; 2009 Nov; 76(5):1094-103. PubMed ID: 19706730
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.
    Raphemot R; Lonergan DF; Nguyen TT; Utley T; Lewis LM; Kadakia R; Weaver CD; Gogliotti R; Hopkins C; Lindsley CW; Denton JS
    Front Pharmacol; 2011; 2():75. PubMed ID: 22275899
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inward rectifier K(+) current in human bronchial smooth muscle cells: inhibition with antisense oligonucleotides targeted to Kir2.1 mRNA.
    Oonuma H; Iwasawa K; Iida H; Nagata T; Imuta H; Morita Y; Yamamoto K; Nagai R; Omata M; Nakajima T
    Am J Respir Cell Mol Biol; 2002 Mar; 26(3):371-9. PubMed ID: 11867346
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inward rectifier potassium (Kir) channels in the soybean aphid Aphis glycines: Functional characterization, pharmacology, and toxicology.
    Piermarini PM; Inocente EA; Acosta N; Hopkins CR; Denton JS; Michel AP
    J Insect Physiol; 2018 Oct; 110():57-65. PubMed ID: 30196125
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors: A Brief History of Medicinal Chemistry Approaches To Develop Novel Diuretic Therapeutics.
    Aretz CD; Vadukoot AK; Hopkins CR
    J Med Chem; 2019 Oct; 62(19):8682-8694. PubMed ID: 31034224
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inward rectifier potassium (Kir2.1) channels as end-stage boosters of endothelium-dependent vasodilators.
    Sonkusare SK; Dalsgaard T; Bonev AD; Nelson MT
    J Physiol; 2016 Jun; 594(12):3271-85. PubMed ID: 26840527
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The inwardly rectifying potassium channel Kir1.1: development of functional assays to identify and characterize channel inhibitors.
    Felix JP; Priest BT; Solly K; Bailey T; Brochu RM; Liu CJ; Kohler MG; Kiss L; Alonso-Galicia M; Tang H; Pasternak A; Kaczorowski GJ; Garcia ML
    Assay Drug Dev Technol; 2012 Oct; 10(5):417-31. PubMed ID: 22881347
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pore Polarity and Charge Determine Differential Block of Kir1.1 and Kir7.1 Potassium Channels by Small-Molecule Inhibitor VU590.
    Kharade SV; Sheehan JH; Figueroa EE; Meiler J; Denton JS
    Mol Pharmacol; 2017 Sep; 92(3):338-346. PubMed ID: 28619748
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting the inward-rectifier potassium channel ROMK in cardiovascular disease.
    Garcia ML; Kaczorowski GJ
    Curr Opin Pharmacol; 2014 Apr; 15():1-6. PubMed ID: 24721647
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spermine is fit to block inward rectifier (Kir) channels.
    Stanfield PR; Sutcliffe MJ
    J Gen Physiol; 2003 Nov; 122(5):481-4. PubMed ID: 14581580
    [No Abstract]   [Full Text] [Related]  

  • 20. Characterization of Kir1.1 channels with the use of a radiolabeled derivative of tertiapin.
    Felix JP; Liu J; Schmalhofer WA; Bailey T; Bednarek MA; Kinkel S; Weinglass AB; Kohler M; Kaczorowski GJ; Priest BT; Garcia ML
    Biochemistry; 2006 Aug; 45(33):10129-39. PubMed ID: 16906771
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.