616 related articles for article (PubMed ID: 2054779)
1. Enhanced repair of O6-methylguanine DNA adducts in the liver of transgenic mice expressing the ada gene.
Dumenco LL; Arce C; Norton K; Yun J; Wagner T; Gerson SL
Cancer Res; 1991 Jul; 51(13):3391-8. PubMed ID: 2054779
[TBL] [Abstract][Full Text] [Related]
2. Rapid repair of O6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas.
Liu L; Allay E; Dumenco LL; Gerson SL
Cancer Res; 1994 Sep; 54(17):4648-52. PubMed ID: 8062258
[TBL] [Abstract][Full Text] [Related]
3. High level, regulated expression of the chimeric P-enolpyruvate carboxykinase (GTP)-bacterial O6-alkylguanine-DNA alkyltransferase (ada) gene in transgenic mice.
Lim IK; Dumenco LL; Yun J; Donovan C; Warman B; Gorodetzkaya N; Wagner TE; Clapp DW; Hanson RW; Gerson SL
Cancer Res; 1990 Mar; 50(6):1701-8. PubMed ID: 2407342
[TBL] [Abstract][Full Text] [Related]
4. Comparison of the rates of repair of O6-alkylguanines in DNA by rat liver and bacterial O6-alkylguanine-DNA alkyltransferase.
Pegg AE; Scicchitano D; Dolan ME
Cancer Res; 1984 Sep; 44(9):3806-11. PubMed ID: 6378375
[TBL] [Abstract][Full Text] [Related]
5. A novel, sensitive assay for O6-methyl- and O6-ethylguanine in DNA, based on repair by the enzyme O6-alkylguanine-DNA-alkyltransferase in competition with an oligonucleotide containing O6-methylguanine.
Souliotis VL; Kyrtopoulos SA
Cancer Res; 1989 Dec; 49(24 Pt 1):6997-7001. PubMed ID: 2684406
[TBL] [Abstract][Full Text] [Related]
6. Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine.
Dolan ME; Pegg AE; Dumenco LL; Moschel RC; Gerson SL
Carcinogenesis; 1991 Dec; 12(12):2305-9. PubMed ID: 1747932
[TBL] [Abstract][Full Text] [Related]
7. Repair of O6-alkylguanine during DNA synthesis in murine bone marrow hematopoietic precursors.
Gerson SL; Trey JE; Miller K; Benjamin E
Cancer Res; 1987 Jan; 47(1):89-95. PubMed ID: 3539320
[TBL] [Abstract][Full Text] [Related]
8. DNA adducts and the mechanism of carcinogenesis and cytotoxicity of methylating agents of environmental and clinical significance.
Kyrtopoulos SA; Anderson LM; Chhabra SK; Souliotis VL; Pletsa V; Valavanis C; Georgiadis P
Cancer Detect Prev; 1997; 21(5):391-405. PubMed ID: 9307842
[TBL] [Abstract][Full Text] [Related]
9. Induction of rat liver O6-alkylguanine-DNA alkyltransferase following whole body X-irradiation.
Schmerold I; Wiestler OD
Cancer Res; 1986 Jan; 46(1):245-9. PubMed ID: 3509992
[TBL] [Abstract][Full Text] [Related]
10. Accumulation of O6-methylguanine in human blood leukocyte DNA during exposure to procarbazine and its relationships with dose and repair.
Souliotis VL; Kaila S; Boussiotis VA; Pangalis GA; Kyrtopoulos SA
Cancer Res; 1990 May; 50(9):2759-64. PubMed ID: 2328502
[TBL] [Abstract][Full Text] [Related]
11. Reduction of O6-alkylguanine-DNA alkyltransferase activity in HeLa cells treated with O6-alkylguanines.
Dolan ME; Morimoto K; Pegg AE
Cancer Res; 1985 Dec; 45(12 Pt 1):6413-7. PubMed ID: 4063990
[TBL] [Abstract][Full Text] [Related]
12. Transgenic mice expressing the bacterial O6 alkylguanine-DNA alkyltransferase gene: an animal model to study the role of DNA repair in the carcinogenesis of N-nitroso compounds.
Dumenco LL; Donovan C; Warman B; Clapp DW; Lim IK; Yun J; Wagner T; Hanson RW; Gerson SL
Prog Clin Biol Res; 1990; 340A():369-78. PubMed ID: 2388920
[No Abstract] [Full Text] [Related]
13. Regeneration of O6-alkylguanine-DNA alkyltransferase in human lymphocytes after nitrosourea exposure.
Gerson SL
Cancer Res; 1988 Sep; 48(18):5368-73. PubMed ID: 3409258
[TBL] [Abstract][Full Text] [Related]
14. Relevance of environmental alkylating agents to repair protein O6-alkylguanine-DNA alkyltransferase: determination of individual and collective repair capacities of O6-methylguanine.
Oesch F; Klein S
Cancer Res; 1992 Apr; 52(7):1801-3. PubMed ID: 1532345
[TBL] [Abstract][Full Text] [Related]
15. Modulation of O6-alkylguanine-DNA alkyltransferase in rats following intravenous administration of O6-methylguanine.
Dexter EU; Yamashita TS; Donovan C; Gerson SL
Cancer Res; 1989 Jul; 49(13):3520-4. PubMed ID: 2731174
[TBL] [Abstract][Full Text] [Related]
16. Alkyltransferase transgenic mice: probes of chemical carcinogenesis.
Gerson SL; Zaidi NH; Dumenco LL; Allay E; Fan CY; Liu L; O'Connor PJ
Mutat Res; 1994 Jun; 307(2):541-55. PubMed ID: 7514728
[TBL] [Abstract][Full Text] [Related]
17. Potentiation of lymphomagenesis by methylnitrosourea in mice transgenic for LMO1 is blocked by O6-alkylguanine DNA-alkyltransferase.
Allay E; Reese JS; McGuire EA; KoƧ ON; Sedransk N; Gerson SL
Oncogene; 1997 Oct; 15(17):2127-32. PubMed ID: 9366529
[TBL] [Abstract][Full Text] [Related]
18. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
Dosch J; Kaina B
Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539
[TBL] [Abstract][Full Text] [Related]
19. Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea.
Allay E; Veigl M; Gerson SL
Oncogene; 1999 Jun; 18(25):3783-7. PubMed ID: 10391687
[TBL] [Abstract][Full Text] [Related]
20. Efficient repair of O6-ethylguanine, but not O4-ethylthymine or O2-ethylthymine, is dependent upon O6-alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells.
Bronstein SM; Skopek TR; Swenberg JA
Cancer Res; 1992 Apr; 52(7):2008-11. PubMed ID: 1551130
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]