233 related articles for article (PubMed ID: 20567254)
1. Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions.
Ahlin G; Chen L; Lazorova L; Chen Y; Ianculescu AG; Davis RL; Giacomini KM; Artursson P
Pharmacogenomics J; 2011 Dec; 11(6):400-11. PubMed ID: 20567254
[TBL] [Abstract][Full Text] [Related]
2. Sitagliptin attenuates metformin-mediated AMPK phosphorylation through inhibition of organic cation transporters.
Choi MK; Jin QR; Ahn SH; Bae MA; Song IS
Xenobiotica; 2010 Dec; 40(12):817-25. PubMed ID: 20863201
[TBL] [Abstract][Full Text] [Related]
3. The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.
Schlatter E; Mönnich V; Cetinkaya I; Mehrens T; Ciarimboli G; Hirsch JR; Popp C; Koepsell H
J Membr Biol; 2002 Oct; 189(3):237-44. PubMed ID: 12395288
[TBL] [Abstract][Full Text] [Related]
4. Organic cation transporter 1 polymorphisms predict the metabolic response to metformin in women with the polycystic ovary syndrome.
Gambineri A; Tomassoni F; Gasparini DI; Di Rocco A; Mantovani V; Pagotto U; Altieri P; Sanna S; Fulghesu AM; Pasquali R
J Clin Endocrinol Metab; 2010 Oct; 95(10):E204-8. PubMed ID: 20660041
[TBL] [Abstract][Full Text] [Related]
5. Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Ahlin G; Karlsson J; Pedersen JM; Gustavsson L; Larsson R; Matsson P; Norinder U; Bergström CA; Artursson P
J Med Chem; 2008 Oct; 51(19):5932-42. PubMed ID: 18788725
[TBL] [Abstract][Full Text] [Related]
6. Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.
Zolk O; Solbach TF; König J; Fromm MF
Drug Metab Dispos; 2009 Jun; 37(6):1312-8. PubMed ID: 19251820
[TBL] [Abstract][Full Text] [Related]
7. Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin.
Wang DS; Jonker JW; Kato Y; Kusuhara H; Schinkel AH; Sugiyama Y
J Pharmacol Exp Ther; 2002 Aug; 302(2):510-5. PubMed ID: 12130709
[TBL] [Abstract][Full Text] [Related]
8. Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration.
Tzvetkov MV; dos Santos Pereira JN; Meineke I; Saadatmand AR; Stingl JC; Brockmöller J
Biochem Pharmacol; 2013 Sep; 86(5):666-78. PubMed ID: 23835420
[TBL] [Abstract][Full Text] [Related]
9. In vitro interaction of clopidogrel and its hydrolysate with OCT1, OCT2 and OAT1.
Li L; Song F; Tu M; Wang K; Zhao L; Wu X; Zhou H; Xia Z; Jiang H
Int J Pharm; 2014 Apr; 465(1-2):5-10. PubMed ID: 24530383
[TBL] [Abstract][Full Text] [Related]
10. Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function.
Chen L; Takizawa M; Chen E; Schlessinger A; Segenthelar J; Choi JH; Sali A; Kubo M; Nakamura S; Iwamoto Y; Iwasaki N; Giacomini KM
J Pharmacol Exp Ther; 2010 Oct; 335(1):42-50. PubMed ID: 20639304
[TBL] [Abstract][Full Text] [Related]
11. Transport of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells.
Salomon JJ; Endter S; Tachon G; Falson F; Buckley ST; Ehrhardt C
Eur J Pharm Biopharm; 2012 Jun; 81(2):351-9. PubMed ID: 22426135
[TBL] [Abstract][Full Text] [Related]
12. Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.
Shu Y; Sheardown SA; Brown C; Owen RP; Zhang S; Castro RA; Ianculescu AG; Yue L; Lo JC; Burchard EG; Brett CM; Giacomini KM
J Clin Invest; 2007 May; 117(5):1422-31. PubMed ID: 17476361
[TBL] [Abstract][Full Text] [Related]
13. Organic cation transporter 1 variants and gastrointestinal side effects of metformin in patients with Type 2 diabetes.
Dujic T; Causevic A; Bego T; Malenica M; Velija-Asimi Z; Pearson ER; Semiz S
Diabet Med; 2016 Apr; 33(4):511-4. PubMed ID: 26605869
[TBL] [Abstract][Full Text] [Related]
14. Characterization of Calu-3 cell monolayers as a model of bronchial epithelial transport: organic cation interaction studies.
Macdonald C; Shao D; Oli A; Agu RU
J Drug Target; 2013 Jan; 21(1):97-106. PubMed ID: 23050869
[TBL] [Abstract][Full Text] [Related]
15. Effects of tetraalkylammonium compounds with different affinities for organic cation transporters on the pharmacokinetics of metformin.
Choi MK; Jin QR; Jin HE; Shim CK; Cho DY; Shin JG; Song IS
Biopharm Drug Dispos; 2007 Dec; 28(9):501-10. PubMed ID: 17876861
[TBL] [Abstract][Full Text] [Related]
16. Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics.
Shu Y; Brown C; Castro RA; Shi RJ; Lin ET; Owen RP; Sheardown SA; Yue L; Burchard EG; Brett CM; Giacomini KM
Clin Pharmacol Ther; 2008 Feb; 83(2):273-80. PubMed ID: 17609683
[TBL] [Abstract][Full Text] [Related]
17. Effect of pregnane X receptor ligand on pharmacokinetics of substrates of organic cation transporter Oct1 in rats.
Maeda T; Oyabu M; Yotsumoto T; Higashi R; Nagata K; Yamazoe Y; Tamai I
Drug Metab Dispos; 2007 Sep; 35(9):1580-6. PubMed ID: 17553914
[TBL] [Abstract][Full Text] [Related]
18. Inter-Subject Variability in OCT1 Activity in 27 Batches of Cryopreserved Human Hepatocytes and Association with OCT1 mRNA Expression and Genotype.
Fattah S; Shinde AB; Matic M; Baes M; van Schaik RHN; Allegaert K; Parmentier C; Richert L; Augustijns P; Annaert P
Pharm Res; 2017 Jun; 34(6):1309-1319. PubMed ID: 28364304
[TBL] [Abstract][Full Text] [Related]
19. The prototypic pharmacogenetic drug debrisoquine is a substrate of the genetically polymorphic organic cation transporter OCT1.
Saadatmand AR; Tadjerpisheh S; Brockmöller J; Tzvetkov MV
Biochem Pharmacol; 2012 May; 83(10):1427-34. PubMed ID: 22342776
[TBL] [Abstract][Full Text] [Related]
20. Relevance of the OCT1 transporter to the antineoplastic effect of biguanides.
Segal ED; Yasmeen A; Beauchamp MC; Rosenblatt J; Pollak M; Gotlieb WH
Biochem Biophys Res Commun; 2011 Nov; 414(4):694-9. PubMed ID: 21986525
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]