These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 20570249)

  • 1. Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase.
    Yang H; Zhuo JM; Chu J; Chinnici C; Praticò D
    Biol Psychiatry; 2010 Nov; 68(10):922-9. PubMed ID: 20570249
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease.
    Kobayashi DT; Chen KS
    Genes Brain Behav; 2005 Apr; 4(3):173-96. PubMed ID: 15810905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A role for 12/15 lipoxygenase in the amyloid beta precursor protein metabolism.
    Succol F; Praticò D
    J Neurochem; 2007 Oct; 103(1):380-7. PubMed ID: 17877641
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacologic blockade of 12/15-lipoxygenase ameliorates memory deficits, Aβ and tau neuropathology in the triple-transgenic mice.
    Chu J; Li JG; Giannopoulos PF; Blass BE; Childers W; Abou-Gharbia M; Praticò D
    Mol Psychiatry; 2015 Nov; 20(11):1329-38. PubMed ID: 25560760
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rapid cerebral amyloid binding by Aβ antibodies infused into β-amyloid precursor protein transgenic mice.
    Winkler DT; Abramowski D; Danner S; Zurini M; Paganetti P; Tolnay M; Staufenbiel M
    Biol Psychiatry; 2010 Nov; 68(10):971-4. PubMed ID: 20359696
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB
    J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alzheimer's disease.
    Querfurth HW; LaFerla FM
    N Engl J Med; 2010 Jan; 362(4):329-44. PubMed ID: 20107219
    [No Abstract]   [Full Text] [Related]  

  • 9. 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.
    Imbimbo BP; Del Giudice E; Colavito D; D'Arrigo A; Dalle Carbonare M; Villetti G; Facchinetti F; Volta R; Pietrini V; Baroc MF; Serneels L; De Strooper B; Leon A
    J Pharmacol Exp Ther; 2007 Dec; 323(3):822-30. PubMed ID: 17895400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The 12/15-lipoxygenase as an emerging therapeutic target for Alzheimer's disease.
    Joshi YB; Giannopoulos PF; Praticò D
    Trends Pharmacol Sci; 2015 Mar; 36(3):181-186. PubMed ID: 25708815
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High dietary consumption of trans fatty acids decreases brain docosahexaenoic acid but does not alter amyloid-beta and tau pathologies in the 3xTg-AD model of Alzheimer's disease.
    Phivilay A; Julien C; Tremblay C; Berthiaume L; Julien P; Giguère Y; Calon F
    Neuroscience; 2009 Mar; 159(1):296-307. PubMed ID: 19135506
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Progressive neuronal loss and behavioral impairments of transgenic C57BL/6 inbred mice expressing the carboxy terminus of amyloid precursor protein.
    Lee KW; Im JY; Song JS; Lee SH; Lee HJ; Ha HY; Koh JY; Gwag BJ; Yang SD; Paik SG; Han PL
    Neurobiol Dis; 2006 Apr; 22(1):10-24. PubMed ID: 16289866
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure.
    Hahn S; Brüning T; Ness J; Czirr E; Baches S; Gijsen H; Korth C; Pietrzik CU; Bulic B; Weggen S
    J Neurochem; 2011 Feb; 116(3):385-95. PubMed ID: 21091478
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glucocorticoids increase impairments in learning and memory due to elevated amyloid precursor protein expression and neuronal apoptosis in 12-month old mice.
    Li WZ; Li WP; Yao YY; Zhang W; Yin YY; Wu GC; Gong HL
    Eur J Pharmacol; 2010 Feb; 628(1-3):108-15. PubMed ID: 19948164
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Immunotherapy against APP beta-secretase cleavage site improves cognitive function and reduces neuroinflammation in Tg2576 mice without a significant effect on brain abeta levels.
    Rakover I; Arbel M; Solomon B
    Neurodegener Dis; 2007; 4(5):392-402. PubMed ID: 17536186
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Concomitant detection of beta-amyloid peptides with N-terminal truncation and different C-terminal endings in cortical plaques from cases with Alzheimer's disease, senile monkeys and triple transgenic mice.
    Härtig W; Goldhammer S; Bauer U; Wegner F; Wirths O; Bayer TA; Grosche J
    J Chem Neuroanat; 2010 Sep; 40(1):82-92. PubMed ID: 20347032
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress.
    Lee KW; Kim JB; Seo JS; Kim TK; Im JY; Baek IS; Kim KS; Lee JK; Han PL
    J Neurochem; 2009 Jan; 108(1):165-75. PubMed ID: 19012747
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuroprotective mechanism conferred by 17beta-estradiol on the biochemical basis of Alzheimer's disease.
    Amtul Z; Wang L; Westaway D; Rozmahel RF
    Neuroscience; 2010 Aug; 169(2):781-6. PubMed ID: 20493928
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress.
    Praticò D; Zhukareva V; Yao Y; Uryu K; Funk CD; Lawson JA; Trojanowski JQ; Lee VM
    Am J Pathol; 2004 May; 164(5):1655-62. PubMed ID: 15111312
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Beta/A4-type amyloid protein in Alzheimer's disease and cerebral amyloid angiopathies].
    Hirai S; Okamoto K
    Nihon Naika Gakkai Zasshi; 1993 Sep; 82(9):1424-9. PubMed ID: 8245639
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 9.