These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

599 related articles for article (PubMed ID: 20576573)

  • 21. Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors.
    Barreca ML; Ferro S; Rao A; De Luca L; Zappalà M; Monforte AM; Debyser Z; Witvrouw M; Chimirri A
    J Med Chem; 2005 Nov; 48(22):7084-8. PubMed ID: 16250669
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase.
    Sweeney ZK; Harris SF; Arora SF; Javanbakht H; Li Y; Fretland J; Davidson JP; Billedeau JR; Gleason SK; Hirschfeld D; Kennedy-Smith JJ; Mirzadegan T; Roetz R; Smith M; Sperry S; Suh JM; Wu J; Tsing S; Villaseñor AG; Paul A; Su G; Heilek G; Hang JQ; Zhou AS; Jernelius JA; Zhang FJ; Klumpp K
    J Med Chem; 2008 Dec; 51(23):7449-58. PubMed ID: 19007201
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design and optimization of tricyclic phtalimide analogues as novel inhibitors of HIV-1 integrase.
    Verschueren WG; Dierynck I; Amssoms KI; Hu L; Boonants PM; Pille GM; Daeyaert FF; Hertogs K; Surleraux DL; Wigerinck PB
    J Med Chem; 2005 Mar; 48(6):1930-40. PubMed ID: 15771437
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Benzyl amide-ketoacid inhibitors of HIV-integrase.
    Walker MA; Johnson T; Naidu BN; Banville J; Remillard R; Plamondon S; Martel A; Li C; Torri A; Samanta H; Lin Z; Dicker I; Krystal M; Meanwell NA
    Bioorg Med Chem Lett; 2007 Sep; 17(17):4886-90. PubMed ID: 17604626
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Dimerization inhibitors of HIV-1 reverse transcriptase, protease and integrase: a single mode of inhibition for the three HIV enzymes?
    Camarasa MJ; Velázquez S; San-Félix A; Pérez-Pérez MJ; Gago F
    Antiviral Res; 2006 Sep; 71(2-3):260-7. PubMed ID: 16872687
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis and evaluation of 3-hydroxy-3-phenylpropanoate ester–AZT conjugates as potential dual-action HIV-1 Integrase and Reverse Transcriptase inhibitors.
    Manyeruke MH; Olomola TO; Majumder S; Abrahams S; Isaacs M; Mautsa N; Mosebi S; Mnkandhla D; Hewer R; Hoppe HC; Klein R; Kaye PT
    Bioorg Med Chem; 2015 Dec; 23(24):7521-8. PubMed ID: 26775541
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A platform for designing HIV integrase inhibitors. Part 2: a two-metal binding model as a potential mechanism of HIV integrase inhibitors.
    Kawasuji T; Fuji M; Yoshinaga T; Sato A; Fujiwara T; Kiyama R
    Bioorg Med Chem; 2006 Dec; 14(24):8420-9. PubMed ID: 17005407
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design, synthesis, and SAR of naphthyl-substituted Diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Liang YH; Feng XQ; Zeng ZS; Chen FE; Balzarini J; Pannecouque C; De Clercq E
    ChemMedChem; 2009 Sep; 4(9):1537-45. PubMed ID: 19591191
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase--structure-activity relationships and crystallographic analysis.
    Kirschberg TA; Balakrishnan M; Huang W; Hluhanich R; Kutty N; Liclican AC; McColl DJ; Squires NH; Lansdon EB
    Bioorg Med Chem Lett; 2008 Feb; 18(3):1131-4. PubMed ID: 18083512
    [TBL] [Abstract][Full Text] [Related]  

  • 30. 5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase.
    Sun L; Gao P; Dong G; Zhang X; Cheng X; Ding X; Wang X; Daelemans D; De Clercq E; Pannecouque C; Menéndez-Arias L; Zhan P; Liu X
    Eur J Med Chem; 2018 Jul; 155():714-724. PubMed ID: 29940462
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Conformational study of the HIV-1 reverse transcriptase inhibitor 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
    Lawtrakul L; Hannongbua S; Beyer A; Wolschann P
    Biol Chem; 1999 Feb; 380(2):265-7. PubMed ID: 10195434
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants.
    Su DS; Lim JJ; Tinney E; Wan BL; Young MB; Anderson KD; Rudd D; Munshi V; Bahnck C; Felock PJ; Lu M; Lai MT; Touch S; Moyer G; Distefano DJ; Flynn JA; Liang Y; Sanchez R; Prasad S; Yan Y; Perlow-Poehnelt R; Torrent M; Miller M; Vacca JP; Williams TM; Anthony NJ
    Bioorg Med Chem Lett; 2009 Sep; 19(17):5119-23. PubMed ID: 19631528
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Lead optimization at C-2 and N-3 positions of thiazolidin-4-ones as HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Murugesan V; Tiwari VS; Saxena R; Tripathi R; Paranjape R; Kulkarni S; Makwana N; Suryawanshi R; Katti SB
    Bioorg Med Chem; 2011 Nov; 19(22):6919-26. PubMed ID: 21982685
    [TBL] [Abstract][Full Text] [Related]  

  • 34. QSAR for anti-HIV activity of HEPT derivatives.
    Bazoui H; Zahouily M; Boulajaaj S; Sebti S; Zakarya D
    SAR QSAR Environ Res; 2002 Oct; 13(6):567-77. PubMed ID: 12479372
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The design and synthesis of N-1-alkylated-5-aminoarylalkylsubstituted-6-methyluracils as potential non-nucleoside HIV-1 RT inhibitors.
    Lu X; Chen Y; Guo Y; Liu Z; Shi Y; Xu Y; Wang X; Zhang Z; Liu J
    Bioorg Med Chem; 2007 Dec; 15(23):7399-407. PubMed ID: 17870545
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis and biological evaluation of (±)-benzhydrol derivatives as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ma XD; Zhang X; Yang SQ; Dai HF; Yang LM; Gu SX; Zheng YT; He QQ; Chen FE
    Bioorg Med Chem; 2011 Aug; 19(16):4704-9. PubMed ID: 21788138
    [TBL] [Abstract][Full Text] [Related]  

  • 37. 4-Hydroxy-5-pyrrolinone-3-carboxamide HIV-1 integrase inhibitors.
    Pace P; Spieser SA; Summa V
    Bioorg Med Chem Lett; 2008 Jul; 18(14):3865-9. PubMed ID: 18595690
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
    Dayam R; Sanchez T; Clement O; Shoemaker R; Sei S; Neamati N
    J Med Chem; 2005 Jan; 48(1):111-20. PubMed ID: 15634005
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
    Hopkins AL; Ren J; Milton J; Hazen RJ; Chan JH; Stuart DI; Stammers DK
    J Med Chem; 2004 Nov; 47(24):5912-22. PubMed ID: 15537346
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dissecting Tn5 transposition using HIV-1 integrase diketoacid inhibitors.
    Czyz A; Stillmock KA; Hazuda DJ; Reznikoff WS
    Biochemistry; 2007 Sep; 46(38):10776-89. PubMed ID: 17725323
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 30.