These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 20580705)

  • 1. Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways.
    Li Y; Wang Q; Yao X; Li Y
    Eur J Pharmacol; 2010 Aug; 640(1-3):46-54. PubMed ID: 20580705
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
    Gupta A; Mugundu GM; Desai PB; Thummel KE; Unadkat JD
    Drug Metab Dispos; 2008 Jun; 36(6):1172-80. PubMed ID: 18332086
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro.
    Feng D; Tang T; Fan R; Luo J; Cui H; Wang Y; Gan P
    BMC Complement Altern Med; 2018 Dec; 18(1):345. PubMed ID: 30594244
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells.
    Liu CL; Lim YP; Hu ML
    Mar Drugs; 2012 Jan; 10(1):242-257. PubMed ID: 22363234
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.
    Li L; Stanton JD; Tolson AH; Luo Y; Wang H
    Pharm Res; 2009 Apr; 26(4):872-82. PubMed ID: 19034627
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
    Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Scutellarin Mediates Cytochrome P450 3A4 and 2C19 Expression via Pregnane X Receptor and Constitutive Androstane Receptor.
    Huang H; Cao C; Miao Z; Yang X; Lai Y
    Curr Mol Pharmacol; 2023; 16(6):640-653. PubMed ID: 36017831
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion.
    Masuyama H; Suwaki N; Tateishi Y; Nakatsukasa H; Segawa T; Hiramatsu Y
    Mol Endocrinol; 2005 May; 19(5):1170-80. PubMed ID: 15650019
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors.
    Zhang X; Meng R; Wang H; Xing J
    Planta Med; 2020 Aug; 86(12):867-875. PubMed ID: 32557519
    [No Abstract]   [Full Text] [Related]  

  • 11. Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals.
    Satsu H; Hiura Y; Mochizuki K; Hamada M; Shimizu M
    J Agric Food Chem; 2008 Jul; 56(13):5366-73. PubMed ID: 18540626
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA.
    Yu C; Ye S; Sun H; Liu Y; Gao L; Shen C; Chen S; Zeng S
    Chem Biol Interact; 2009 Jan; 177(1):58-64. PubMed ID: 18805405
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway.
    Awortwe C; Manda VK; Avonto C; Khan SI; Khan IA; Walker LA; Bouic PJ; Rosenkranz B
    Xenobiotica; 2015 Mar; 45(3):218-29. PubMed ID: 25377539
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor.
    Burk O; Arnold KA; Nussler AK; Schaeffeler E; Efimova E; Avery BA; Avery MA; Fromm MF; Eichelbaum M
    Mol Pharmacol; 2005 Jun; 67(6):1954-65. PubMed ID: 15761118
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
    Hu Q; Yao N; Wu J; Liu M; Liu F; Zhang H; Xiong Y; Xia C
    Biochem Pharmacol; 2019 Jan; 159():32-39. PubMed ID: 30414935
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
    Song X; Xie M; Zhang H; Li Y; Sachdeva K; Yan B
    Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
    Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tamoxifen activates CYP3A4 and MDR1 genes through steroid and xenobiotic receptor in breast cancer cells.
    Nagaoka R; Iwasaki T; Rokutanda N; Takeshita A; Koibuchi Y; Horiguchi J; Shimokawa N; Iino Y; Morishita Y; Koibuchi N
    Endocrine; 2006 Dec; 30(3):261-8. PubMed ID: 17526937
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
    Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
    Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR.
    Pondugula SR; Flannery PC; Abbott KL; Coleman ES; Mani S; Samuel T; Xie W
    Toxicol Lett; 2015 Feb; 232(3):580-9. PubMed ID: 25542144
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.