Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

875 related articles for article (PubMed ID: 20580954)

  • 1. Functional and biological analysis of Bcl-xL expression in human osteosarcoma.
    Wang ZX; Yang JS; Pan X; Wang JR; Li J; Yin YM; De W
    Bone; 2010 Aug; 47(2):445-54. PubMed ID: 20580954
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies.
    Choudhary GS; Al-Harbi S; Mazumder S; Hill BT; Smith MR; Bodo J; Hsi ED; Almasan A
    Cell Death Dis; 2015 Jan; 6(1):e1593. PubMed ID: 25590803
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pan-Bcl-2 blocker obatoclax promotes the expression of Puma, Noxa, and Bim mRNA and induces apoptosis in neoplastic mast cells.
    Peter B; Cerny-Reiterer S; Hadzijusufovic E; Schuch K; Stefanzl G; Eisenwort G; Gleixner KV; Hoermann G; Mayerhofer M; Kundi M; Baumgartner S; Sperr WR; Pickl WF; Willmann M; Valent P
    J Leukoc Biol; 2014 Jan; 95(1):95-104. PubMed ID: 24052572
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Myeloid cell leukemia-1 is an important apoptotic survival factor in triple-negative breast cancer.
    Goodwin CM; Rossanese OW; Olejniczak ET; Fesik SW
    Cell Death Differ; 2015 Dec; 22(12):2098-106. PubMed ID: 26045046
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells.
    Okamoto K; Zaanan A; Kawakami H; Huang S; Sinicrope FA
    Mol Cancer Res; 2015 Apr; 13(4):659-69. PubMed ID: 25548100
    [TBL] [Abstract][Full Text] [Related]  

  • 6. c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1.
    Campone M; Noël B; Couriaud C; Grau M; Guillemin Y; Gautier F; Gouraud W; Charbonnel C; Campion L; Jézéquel P; Braun F; Barré B; Coqueret O; Barillé-Nion S; Juin P
    Mol Cancer; 2011 Sep; 10():110. PubMed ID: 21899728
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular analysis of functional redundancy among anti-apoptotic Bcl-2 proteins and its role in cancer cell survival.
    Eichhorn JM; Alford SE; Sakurikar N; Chambers TC
    Exp Cell Res; 2014 Apr; 322(2):415-24. PubMed ID: 24556425
    [TBL] [Abstract][Full Text] [Related]  

  • 8. c-Myc overexpression sensitizes Bim-mediated Bax activation for apoptosis induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through regulating Bcl-2/Bcl-xL expression.
    Jiang X; Tsang YH; Yu Q
    Int J Biochem Cell Biol; 2007; 39(5):1016-25. PubMed ID: 17331788
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MicroRNA-133a, downregulated in osteosarcoma, suppresses proliferation and promotes apoptosis by targeting Bcl-xL and Mcl-1.
    Ji F; Zhang H; Wang Y; Li M; Xu W; Kang Y; Wang Z; Wang Z; Cheng P; Tong D; Li C; Tang H
    Bone; 2013 Sep; 56(1):220-6. PubMed ID: 23756231
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TGFbeta-mediated apoptosis of Burkitt's lymphoma BL41 cells is associated with the relocation of mitochondrial BimEL.
    Clybouw C; Mchichi BE; Hadji A; Portier A; Auffredou MT; Arnoult D; Leca G; Vazquez A
    Oncogene; 2008 May; 27(24):3446-56. PubMed ID: 18193085
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival.
    Rubert J; Qian Z; Andraos R; Guthy DA; Radimerski T
    BMC Cancer; 2011 Jan; 11():24. PubMed ID: 21247487
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosis.
    Wang X; Xing D; Liu L; Chen WR
    FEBS Lett; 2009 Jun; 583(12):1873-9. PubMed ID: 19427863
    [TBL] [Abstract][Full Text] [Related]  

  • 13. siRNA-mediated Bcl-2 and Bcl-xl gene silencing sensitizes human hepatoblastoma cells to chemotherapeutic drugs.
    Lei XY; Zhong M; Feng LF; Zhu BY; Tang SS; Liao DF
    Clin Exp Pharmacol Physiol; 2007; 34(5-6):450-6. PubMed ID: 17439414
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone deacetylase inhibitor potentiates chemotherapy-induced apoptosis through Bim upregulation in Burkitt's lymphoma cells.
    Dos Santos Ferreira AC; Fernandes RA; Kwee JK; Klumb CE
    J Cancer Res Clin Oncol; 2012 Feb; 138(2):317-25. PubMed ID: 22131152
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.
    Zantl N; Weirich G; Zall H; Seiffert BM; Fischer SF; Kirschnek S; Hartmann C; Fritsch RM; Gillissen B; Daniel PT; Häcker G
    Oncogene; 2007 Oct; 26(49):7038-48. PubMed ID: 17486061
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism.
    Zaanan A; Okamoto K; Kawakami H; Khazaie K; Huang S; Sinicrope FA
    J Biol Chem; 2015 Sep; 290(39):23838-49. PubMed ID: 26245900
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lipoic acid decreases Mcl-1, Bcl-xL and up regulates Bim on ovarian carcinoma cells leading to cell death.
    Kafara P; Icard P; Guillamin M; Schwartz L; Lincet H
    J Ovarian Res; 2015 Jun; 8():36. PubMed ID: 26063499
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel gene P28GANK confers multidrug resistance by modulating the expression of MDR-1, Bcl-2 and Bax in osteosarcoma cells.
    Wang G; Rong J; Zhou Z; Duo J
    Mol Biol (Mosk); 2010; 44(6):1010-7. PubMed ID: 21287809
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Select Bcl-2 antagonism restores chemotherapy sensitivity in high-risk neuroblastoma.
    Tanos R; Karmali D; Nalluri S; Goldsmith KC
    BMC Cancer; 2016 Feb; 16():97. PubMed ID: 26874859
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The BH3-only protein Bim(L) overrides Bcl-2-mediated apoptosis resistance in melanoma cells.
    Plötz M; Gillissen B; Quast SA; Berger A; Daniel PT; Eberle J
    Cancer Lett; 2013 Jul; 335(1):100-8. PubMed ID: 23402819
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 44.