167 related articles for article (PubMed ID: 20581436)
1. ATM engages the TSC2/mTORC1 signaling node to regulate autophagy.
Alexander A; Kim J; Walker CL
Autophagy; 2010 Jul; 6(5):672-3. PubMed ID: 20581436
[TBL] [Abstract][Full Text] [Related]
2. Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.
Tripathi DN; Chowdhury R; Trudel LJ; Tee AR; Slack RS; Walker CL; Wogan GN
Proc Natl Acad Sci U S A; 2013 Aug; 110(32):E2950-7. PubMed ID: 23878245
[TBL] [Abstract][Full Text] [Related]
3. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
Alexander A; Cai SL; Kim J; Nanez A; Sahin M; MacLean KH; Inoki K; Guan KL; Shen J; Person MD; Kusewitt D; Mills GB; Kastan MB; Walker CL
Proc Natl Acad Sci U S A; 2010 Mar; 107(9):4153-8. PubMed ID: 20160076
[TBL] [Abstract][Full Text] [Related]
4. Differential localization of ATM is correlated with activation of distinct downstream signaling pathways.
Alexander A; Walker CL
Cell Cycle; 2010 Sep; 9(18):3685-6. PubMed ID: 20890104
[TBL] [Abstract][Full Text] [Related]
5. Regulation of mammalian target of rapamycin complex 1 (mTORC1) by hypoxia: causes and consequences.
Cam H; Houghton PJ
Target Oncol; 2011 Jun; 6(2):95-102. PubMed ID: 21499767
[TBL] [Abstract][Full Text] [Related]
6. A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Zhang J; Kim J; Alexander A; Cai S; Tripathi DN; Dere R; Tee AR; Tait-Mulder J; Di Nardo A; Han JM; Kwiatkowski E; Dunlop EA; Dodd KM; Folkerth RD; Faust PL; Kastan MB; Sahin M; Walker CL
Nat Cell Biol; 2013 Oct; 15(10):1186-96. PubMed ID: 23955302
[TBL] [Abstract][Full Text] [Related]
7. mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.
Cam H; Easton JB; High A; Houghton PJ
Mol Cell; 2010 Nov; 40(4):509-20. PubMed ID: 21095582
[TBL] [Abstract][Full Text] [Related]
8. Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
Parkhitko AA; Priolo C; Coloff JL; Yun J; Wu JJ; Mizumura K; Xu W; Malinowska IA; Yu J; Kwiatkowski DJ; Locasale JW; Asara JM; Choi AM; Finkel T; Henske EP
Mol Cancer Res; 2014 Jan; 12(1):48-57. PubMed ID: 24296756
[TBL] [Abstract][Full Text] [Related]
9. MicroRNA-18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells.
Qased AB; Yi H; Liang N; Ma S; Qiao S; Liu X
Mol Med Rep; 2013 Feb; 7(2):559-64. PubMed ID: 23229340
[TBL] [Abstract][Full Text] [Related]
10. New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress.
Chen BP; Li M; Asaithamby A
Cancer Lett; 2012 Dec; 327(1-2):103-10. PubMed ID: 22155347
[TBL] [Abstract][Full Text] [Related]
11. mTOR-dependent cell survival mechanisms.
Hung CM; Garcia-Haro L; Sparks CA; Guertin DA
Cold Spring Harb Perspect Biol; 2012 Dec; 4(12):. PubMed ID: 23124837
[TBL] [Abstract][Full Text] [Related]
12. Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling.
Halicka HD; Zhao H; Li J; Lee YS; Hsieh TC; Wu JM; Darzynkiewicz Z
Aging (Albany NY); 2012 Dec; 4(12):952-65. PubMed ID: 23363784
[TBL] [Abstract][Full Text] [Related]
13. All stressed out without ATM kinase.
Perry JJ; Tainer JA
Sci Signal; 2011 Apr; 4(167):pe18. PubMed ID: 21467296
[TBL] [Abstract][Full Text] [Related]
14. LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
Shaw RJ
Acta Physiol (Oxf); 2009 May; 196(1):65-80. PubMed ID: 19245654
[TBL] [Abstract][Full Text] [Related]
15. Loss of TSC2 confers resistance to ceramide and nutrient deprivation.
Guenther GG; Liu G; Ramirez MU; McMonigle RJ; Kim SM; McCracken AN; Joo Y; Ushach I; Nguyen NL; Edinger AL
Oncogene; 2014 Apr; 33(14):1776-87. PubMed ID: 23604129
[TBL] [Abstract][Full Text] [Related]
16. ATM functions at the peroxisome to induce pexophagy in response to ROS.
Zhang J; Tripathi DN; Jing J; Alexander A; Kim J; Powell RT; Dere R; Tait-Mulder J; Lee JH; Paull TT; Pandita RK; Charaka VK; Pandita TK; Kastan MB; Walker CL
Nat Cell Biol; 2015 Oct; 17(10):1259-1269. PubMed ID: 26344566
[TBL] [Abstract][Full Text] [Related]
17. Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK.
Avivar-Valderas A; Bobrovnikova-Marjon E; Alan Diehl J; Bardeesy N; Debnath J; Aguirre-Ghiso JA
Oncogene; 2013 Oct; 32(41):4932-40. PubMed ID: 23160380
[TBL] [Abstract][Full Text] [Related]
18. Lysosomal recruitment of TSC2 is a universal response to cellular stress.
Demetriades C; Plescher M; Teleman AA
Nat Commun; 2016 Feb; 7():10662. PubMed ID: 26868506
[TBL] [Abstract][Full Text] [Related]
19. Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.
Yoon JH; Ahn SG; Lee BH; Jung SH; Oh SH
Biochem Pharmacol; 2012 Mar; 83(6):747-57. PubMed ID: 22226932
[TBL] [Abstract][Full Text] [Related]
20. Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine.
Johnson CE; Hunt DK; Wiltshire M; Herbert TP; Sampson JR; Errington RJ; Davies DM; Tee AR
Mol Oncol; 2015 Mar; 9(3):675-88. PubMed ID: 25498902
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
