BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 20581863)

  • 1. Dichotomy in NF-kappaB signaling and chemoresistance in immunoglobulin variable heavy-chain-mutated versus unmutated CLL cells upon CD40/TLR9 triggering.
    Tromp JM; Tonino SH; Elias JA; Jaspers A; Luijks DM; Kater AP; van Lier RA; van Oers MH; Eldering E
    Oncogene; 2010 Sep; 29(36):5071-82. PubMed ID: 20581863
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia.
    Tromp JM; Geest CR; Breij EC; Elias JA; van Laar J; Luijks DM; Kater AP; Beaumont T; van Oers MH; Eldering E
    Clin Cancer Res; 2012 Jan; 18(2):487-98. PubMed ID: 22128299
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells.
    Coscia M; Pantaleoni F; Riganti C; Vitale C; Rigoni M; Peola S; Castella B; Foglietta M; Griggio V; Drandi D; Ladetto M; Bosia A; Boccadoro M; Massaia M
    Leukemia; 2011 May; 25(5):828-37. PubMed ID: 21372840
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Valproic acid induces apoptosis in chronic lymphocytic leukemia cells through activation of the death receptor pathway and potentiates TRAIL response.
    Lagneaux L; Gillet N; Stamatopoulos B; Delforge A; Dejeneffe M; Massy M; Meuleman N; Kentos A; Martiat P; Willems L; Bron D
    Exp Hematol; 2007 Oct; 35(10):1527-37. PubMed ID: 17697742
    [TBL] [Abstract][Full Text] [Related]  

  • 5. VH gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia.
    Aleskog A; Tobin G; Laurell A; Thunberg U; Lindhagen E; Roos G; Nilsson K; Nygren P; Sundström C; Höglund M; Larsson R; Rosenquist R
    Eur J Haematol; 2004 Dec; 73(6):407-11. PubMed ID: 15522062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bone marrow infiltration pattern in B-cell chronic lymphocytic leukemia is related to immunoglobulin heavy-chain variable region mutation status and expression of 70-kd zeta-associated protein (ZAP-70).
    Schade U; Bock O; Vornhusen S; Jäger A; Büsche G; Lehmann U; Kreipe H
    Hum Pathol; 2006 Sep; 37(9):1153-61. PubMed ID: 16938520
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex.
    Maas C; Tromp JM; van Laar J; Thijssen R; Elias JA; Malara A; Krippner-Heidenreich A; Silke J; van Oers MH; Eldering E
    Cell Death Dis; 2013 Aug; 4(8):e782. PubMed ID: 23990022
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction with vascular endothelium enhances survival in primary chronic lymphocytic leukemia cells via NF-kappaB activation and de novo gene transcription.
    Buggins AG; Pepper C; Patten PE; Hewamana S; Gohil S; Moorhead J; Folarin N; Yallop D; Thomas NS; Mufti GJ; Fegan C; Devereux S
    Cancer Res; 2010 Oct; 70(19):7523-33. PubMed ID: 20736369
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitogen induced activation, proliferation and surface antigen expression patterns in unmutated and hypermutated chronic lymphocytic leukemia cells.
    Vilpo J; Tobin G; Hulkkonen J; Hurme M; Thunberg U; Sundström C; Vilpo L; Rosenquist R
    Eur J Haematol; 2005 Jul; 75(1):34-40. PubMed ID: 15946308
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia.
    Vogler M; Butterworth M; Majid A; Walewska RJ; Sun XM; Dyer MJ; Cohen GM
    Blood; 2009 Apr; 113(18):4403-13. PubMed ID: 19008458
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ABT-737 resistance in B-cells isolated from chronic lymphocytic leukemia patients and leukemia cell lines is overcome by the pleiotropic kinase inhibitor quercetin through Mcl-1 down-regulation.
    Russo M; Spagnuolo C; Volpe S; Tedesco I; Bilotto S; Russo GL
    Biochem Pharmacol; 2013 Apr; 85(7):927-36. PubMed ID: 23353698
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BCL-6 mutations are associated with immunoglobulin variable heavy chain mutations in B-cell chronic lymphocytic leukemia.
    Pasqualucci L; Neri A; Baldini L; Dalla-Favera R; Migliazza A
    Cancer Res; 2000 Oct; 60(20):5644-8. PubMed ID: 11059755
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CD40 triggering enhances fludarabine-induced apoptosis of chronic lymphocytic leukemia B-cells through autocrine release of tumor necrosis factor-alpha and interferon-gama and tumor necrosis factor receptor-I-II upregulation.
    de Totero D; Tazzari PL; Capaia M; Montera MP; Clavio M; Balleari E; Foa R; Gobbi M
    Haematologica; 2003 Feb; 88(2):148-58. PubMed ID: 12604404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rituximab (chimeric anti-CD20 monoclonal antibody) inhibits the constitutive nuclear factor-{kappa}B signaling pathway in non-Hodgkin's lymphoma B-cell lines: role in sensitization to chemotherapeutic drug-induced apoptosis.
    Jazirehi AR; Huerta-Yepez S; Cheng G; Bonavida B
    Cancer Res; 2005 Jan; 65(1):264-76. PubMed ID: 15665303
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL.
    Haselager M; Thijssen R; West C; Young L; Van Kampen R; Willmore E; Mackay S; Kater A; Eldering E
    Cell Death Differ; 2021 May; 28(5):1658-1668. PubMed ID: 33495554
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The evolutionarily conserved sequence upstream of the human Ig heavy chain S gamma 3 region is an inducible promoter: synergistic activation by CD40 ligand and IL-4 via cooperative NF-kappa B and STAT-6 binding sites.
    Schaffer A; Cerutti A; Shah S; Zan H; Casali P
    J Immunol; 1999 May; 162(9):5327-36. PubMed ID: 10228008
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Immunoglobulin heavy chain variable region gene usage and mutational status of the leukemic B cells in Iranian patients with chronic lymphocytic leukemia.
    Hojjat-Farsangi M; Jeddi-Tehrani M; Razavi SM; Sharifian RA; Mellstedt H; Shokri F; Rabbani H
    Cancer Sci; 2009 Dec; 100(12):2346-53. PubMed ID: 19824994
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IgVH mutational status and clonality analysis of Richter's transformation: diffuse large B-cell lymphoma and Hodgkin lymphoma in association with B-cell chronic lymphocytic leukemia (B-CLL) represent 2 different pathways of disease evolution.
    Mao Z; Quintanilla-Martinez L; Raffeld M; Richter M; Krugmann J; Burek C; Hartmann E; Rudiger T; Jaffe ES; Müller-Hermelink HK; Ott G; Fend F; Rosenwald A
    Am J Surg Pathol; 2007 Oct; 31(10):1605-14. PubMed ID: 17895764
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CD40 stimulation of B-cell chronic lymphocytic leukaemia cells enhances the anti-apoptotic profile, but also Bid expression and cells remain susceptible to autologous cytotoxic T-lymphocyte attack.
    Kater AP; Evers LM; Remmerswaal EB; Jaspers A; Oosterwijk MF; van Lier RA; van Oers MH; Eldering E
    Br J Haematol; 2004 Nov; 127(4):404-15. PubMed ID: 15521917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The miR-17∼92 family regulates the response to Toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes.
    Bomben R; Gobessi S; Dal Bo M; Volinia S; Marconi D; Tissino E; Benedetti D; Zucchetto A; Rossi D; Gaidano G; Del Poeta G; Laurenti L; Efremov DG; Gattei V
    Leukemia; 2012 Jul; 26(7):1584-93. PubMed ID: 22343732
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.