271 related articles for article (PubMed ID: 20585447)
1. Downregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factor.
Kachhap SK; Rosmus N; Collis SJ; Kortenhorst MS; Wissing MD; Hedayati M; Shabbeer S; Mendonca J; Deangelis J; Marchionni L; Lin J; Höti N; Nortier JW; DeWeese TL; Hammers H; Carducci MA
PLoS One; 2010 Jun; 5(6):e11208. PubMed ID: 20585447
[TBL] [Abstract][Full Text] [Related]
2. E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer.
Lu Z; Luo RZ; Peng H; Huang M; Nishmoto A; Hunt KK; Helin K; Liao WS; Yu Y
Oncogene; 2006 Jan; 25(2):230-9. PubMed ID: 16158053
[TBL] [Abstract][Full Text] [Related]
3. Analysis of the genomic response of human prostate cancer cells to histone deacetylase inhibitors.
Kortenhorst MS; Wissing MD; Rodríguez R; Kachhap SK; Jans JJ; Van der Groep P; Verheul HM; Gupta A; Aiyetan PO; van der Wall E; Carducci MA; Van Diest PJ; Marchionni L
Epigenetics; 2013 Sep; 8(9):907-20. PubMed ID: 23880963
[TBL] [Abstract][Full Text] [Related]
4. Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity.
Tan J; Zhuang L; Jiang X; Yang KK; Karuturi KM; Yu Q
J Biol Chem; 2006 Apr; 281(15):10508-15. PubMed ID: 16476732
[TBL] [Abstract][Full Text] [Related]
5. Synergistic loss of prostate cancer cell viability by coinhibition of HDAC and PARP.
Chao OS; Goodman OB
Mol Cancer Res; 2014 Dec; 12(12):1755-66. PubMed ID: 25127709
[TBL] [Abstract][Full Text] [Related]
6. HDAC Inhibition Induces MicroRNA-182, which Targets RAD51 and Impairs HR Repair to Sensitize Cells to Sapacitabine in Acute Myelogenous Leukemia.
Lai TH; Ewald B; Zecevic A; Liu C; Sulda M; Papaioannou D; Garzon R; Blachly JS; Plunkett W; Sampath D
Clin Cancer Res; 2016 Jul; 22(14):3537-49. PubMed ID: 26858310
[TBL] [Abstract][Full Text] [Related]
7. ATM modulates transcription in response to histone deacetylase inhibition as part of its DNA damage response.
Jang ER; Choi JD; Park MA; Jeong G; Cho H; Lee JS
Exp Mol Med; 2010 Mar; 42(3):195-204. PubMed ID: 20164679
[TBL] [Abstract][Full Text] [Related]
8. Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylases.
Zhang Y; Woodford N; Xia X; Hamburger AW
Nucleic Acids Res; 2003 Apr; 31(8):2168-77. PubMed ID: 12682367
[TBL] [Abstract][Full Text] [Related]
9. Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.
Zhao Y; Tan J; Zhuang L; Jiang X; Liu ET; Yu Q
Proc Natl Acad Sci U S A; 2005 Nov; 102(44):16090-5. PubMed ID: 16243973
[TBL] [Abstract][Full Text] [Related]
10. RNF126 promotes homologous recombination via regulation of E2F1-mediated BRCA1 expression.
Wang Y; Deng O; Feng Z; Du Z; Xiong X; Lai J; Yang X; Xu M; Wang H; Taylor D; Yan C; Chen C; Difeo A; Ma Z; Zhang J
Oncogene; 2016 Mar; 35(11):1363-72. PubMed ID: 26234677
[TBL] [Abstract][Full Text] [Related]
11. Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer.
Feng W; Lu Z; Luo RZ; Zhang X; Seto E; Liao WS; Yu Y
Int J Cancer; 2007 Apr; 120(8):1664-8. PubMed ID: 17230502
[TBL] [Abstract][Full Text] [Related]
12. Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer.
Davis JN; Wojno KJ; Daignault S; Hofer MD; Kuefer R; Rubin MA; Day ML
Cancer Res; 2006 Dec; 66(24):11897-906. PubMed ID: 17178887
[TBL] [Abstract][Full Text] [Related]
13. p53-dependent down-regulation of telomerase is mediated by p21waf1.
Shats I; Milyavsky M; Tang X; Stambolsky P; Erez N; Brosh R; Kogan I; Braunstein I; Tzukerman M; Ginsberg D; Rotter V
J Biol Chem; 2004 Dec; 279(49):50976-85. PubMed ID: 15371422
[TBL] [Abstract][Full Text] [Related]
14. HDAC inhibitor PCI-24781 decreases RAD51 expression and inhibits homologous recombination.
Adimoolam S; Sirisawad M; Chen J; Thiemann P; Ford JM; Buggy JJ
Proc Natl Acad Sci U S A; 2007 Dec; 104(49):19482-7. PubMed ID: 18042714
[TBL] [Abstract][Full Text] [Related]
15. Differences in Expression of Key DNA Damage Repair Genes after Epigenetic-Induced BRCAness Dictate Synthetic Lethality with PARP1 Inhibition.
Wiegmans AP; Yap PY; Ward A; Lim YC; Khanna KK
Mol Cancer Ther; 2015 Oct; 14(10):2321-31. PubMed ID: 26294743
[TBL] [Abstract][Full Text] [Related]
16. Dynamic regulation of Rad51 by E2F1 and p53 in prostate cancer cells upon drug-induced DNA damage under hypoxia.
Wu M; Wang X; McGregor N; Pienta KJ; Zhang J
Mol Pharmacol; 2014 Jun; 85(6):866-76. PubMed ID: 24627085
[TBL] [Abstract][Full Text] [Related]
17. Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661W cells and the retina.
Wallace DM; Cotter TG
J Neurosci Res; 2009 Mar; 87(4):887-905. PubMed ID: 18951482
[TBL] [Abstract][Full Text] [Related]
18. E2F1 enhances glycolysis through suppressing Sirt6 transcription in cancer cells.
Wu M; Seto E; Zhang J
Oncotarget; 2015 May; 6(13):11252-63. PubMed ID: 25816777
[TBL] [Abstract][Full Text] [Related]
19. Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells.
Shim JS; Kim DH; Kwon HJ
Oncogene; 2004 Mar; 23(9):1704-11. PubMed ID: 14661058
[TBL] [Abstract][Full Text] [Related]
20. A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase I.
Yu CC; Pan SL; Chao SW; Liu SP; Hsu JL; Yang YC; Li TK; Huang WJ; Guh JH
Biochem Pharmacol; 2014 Aug; 90(3):320-30. PubMed ID: 24915421
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
