BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 20588253)

  • 1. CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.
    Maruyama T; Kadowaki H; Okamoto N; Nagai A; Naguro I; Matsuzawa A; Shibuya H; Tanaka K; Murata S; Takeda K; Nishitoh H; Ichijo H
    EMBO J; 2010 Aug; 29(15):2501-14. PubMed ID: 20588253
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells.
    Blessing NA; Kasturirangan S; Zink EM; Schroyer AL; Chadee DN
    Cell Signal; 2017 Nov; 39():66-73. PubMed ID: 28757353
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3.
    Blessing NA; Brockman AL; Chadee DN
    Mol Cell Biol; 2014 Aug; 34(16):3132-43. PubMed ID: 24912674
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts.
    Kesavan K; Lobel-Rice K; Sun W; Lapadat R; Webb S; Johnson GL; Garrington TP
    J Cell Physiol; 2004 Apr; 199(1):140-8. PubMed ID: 14978743
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages.
    Wen M; Ma X; Cheng H; Jiang W; Xu X; Zhang Y; Zhang Y; Guo Z; Yu Y; Xu H; Qian C; Cao X; An H
    Nat Commun; 2015 May; 6():7167. PubMed ID: 25981615
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src.
    Sun W; Wei X; Kesavan K; Garrington TP; Fan R; Mei J; Anderson SM; Gelfand EW; Johnson GL
    Mol Cell Biol; 2003 Apr; 23(7):2298-308. PubMed ID: 12640115
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1.
    Takeda AN; Oberoi-Khanuja TK; Glatz G; Schulenburg K; Scholz RP; Carpy A; Macek B; Remenyi A; Rajalingam K
    EMBO J; 2014 Aug; 33(16):1784-801. PubMed ID: 24975362
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation.
    Yamashita M; Ying SX; Zhang GM; Li C; Cheng SY; Deng CX; Zhang YE
    Cell; 2005 Apr; 121(1):101-13. PubMed ID: 15820682
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity.
    Huang J; Tu Z; Lee FS
    Biochem Biophys Res Commun; 2003 Apr; 303(2):532-40. PubMed ID: 12659851
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction.
    Guo Z; Clydesdale G; Cheng J; Kim K; Gan L; McConkey DJ; Ullrich SE; Zhuang Y; Su B
    Mol Cell Biol; 2002 Aug; 22(16):5761-8. PubMed ID: 12138187
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MEKK2 mediates aberrant ERK activation in neurofibromatosis type I.
    Bok S; Shin DY; Yallowitz AR; Eiseman M; Cung M; Xu R; Li N; Sun J; Williams AL; Scott JE; Su B; Shim JH; Greenblatt MB
    Nat Commun; 2020 Nov; 11(1):5704. PubMed ID: 33177525
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis.
    Hammaker DR; Boyle DL; Chabaud-Riou M; Firestein GS
    J Immunol; 2004 Feb; 172(3):1612-8. PubMed ID: 14734742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MEKK2 kinase association with 14-3-3 protein regulates activation of c-Jun N-terminal kinase.
    Matitau AE; Gabor TV; Gill RM; Scheid MP
    J Biol Chem; 2013 Sep; 288(39):28293-302. PubMed ID: 23963453
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The ubiquitin ligase UBE3A dampens ERK pathway signalling in HPV E6 transformed HeLa cells.
    Aguilar-Martinez E; Morrisroe C; Sharrocks AD
    PLoS One; 2015; 10(3):e0119366. PubMed ID: 25815718
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation.
    Cheng J; Yang J; Xia Y; Karin M; Su B
    Mol Cell Biol; 2000 Apr; 20(7):2334-42. PubMed ID: 10713157
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TGF-β inhibits osteogenesis by upregulating the expression of ubiquitin ligase SMURF1 via MAPK-ERK signaling.
    Sun X; Xie Z; Ma Y; Pan X; Wang J; Chen Z; Shi P
    J Cell Physiol; 2018 Jan; 233(1):596-606. PubMed ID: 28322449
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells.
    Chayama K; Papst PJ; Garrington TP; Pratt JC; Ishizuka T; Webb S; Ganiatsas S; Zon LI; Sun W; Johnson GL; Gelfand EW
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4599-604. PubMed ID: 11274363
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression.
    Su B; Cheng J; Yang J; Guo Z
    J Biol Chem; 2001 May; 276(18):14784-90. PubMed ID: 11278622
    [TBL] [Abstract][Full Text] [Related]  

  • 19. E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2.
    Li H; Wang N; Jiang Y; Wang H; Xin Z; An H; Pan H; Ma W; Zhang T; Wang X; Lin W
    EMBO Rep; 2022 Nov; 23(11):e54603. PubMed ID: 36161689
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MEKK2 mediates an alternative β-catenin pathway that promotes bone formation.
    Greenblatt MB; Shin DY; Oh H; Lee KY; Zhai B; Gygi SP; Lotinun S; Baron R; Liu D; Su B; Glimcher LH; Shim JH
    Proc Natl Acad Sci U S A; 2016 Mar; 113(9):E1226-35. PubMed ID: 26884171
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.