BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 20589525)

  • 1. Inhibition of the JAK-2/STAT3 signaling pathway impedes the migratory and invasive potential of human glioblastoma cells.
    Senft C; Priester M; Polacin M; Schröder K; Seifert V; Kögel D; Weissenberger J
    J Neurooncol; 2011 Feb; 101(3):393-403. PubMed ID: 20589525
    [TBL] [Abstract][Full Text] [Related]  

  • 2. On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells.
    Stechishin OD; Luchman HA; Ruan Y; Blough MD; Nguyen SA; Kelly JJ; Cairncross JG; Weiss S
    Neuro Oncol; 2013 Feb; 15(2):198-207. PubMed ID: 23262510
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of STAT3 activity with AG490 decreases the invasion of human pancreatic cancer cells in vitro.
    Huang C; Cao J; Huang KJ; Zhang F; Jiang T; Zhu L; Qiu ZJ
    Cancer Sci; 2006 Dec; 97(12):1417-23. PubMed ID: 17054436
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro.
    Huang C; Yang G; Jiang T; Huang K; Cao J; Qiu Z
    J Exp Clin Cancer Res; 2010 May; 29(1):51. PubMed ID: 20482858
    [TBL] [Abstract][Full Text] [Related]  

  • 5. JAK2/STAT3 targeted therapy suppresses tumor invasion via disruption of the EGFRvIII/JAK2/STAT3 axis and associated focal adhesion in EGFRvIII-expressing glioblastoma.
    Zheng Q; Han L; Dong Y; Tian J; Huang W; Liu Z; Jia X; Jiang T; Zhang J; Li X; Kang C; Ren H
    Neuro Oncol; 2014 Sep; 16(9):1229-43. PubMed ID: 24861878
    [TBL] [Abstract][Full Text] [Related]  

  • 6. JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling.
    Fu LX; Lian QW; Pan JD; Xu ZL; Zhou TM; Ye B
    J Biol Regul Homeost Agents; 2017; 31(1):51-58. PubMed ID: 28337870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas.
    Senft C; Polacin M; Priester M; Seifert V; Kögel D; Weissenberger J
    BMC Cancer; 2010 Sep; 10():491. PubMed ID: 20840775
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Inhibitory effect of AG490 on invasion and metastasis of human pancreatic cancer cells in vitro].
    Huang C; Qiu ZJ; Cao J; Huang KJ; Zhang F; Jiang T; Zhu L; Liu J
    Zhonghua Zhong Liu Za Zhi; 2006 Dec; 28(12):890-3. PubMed ID: 17533737
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [(*)AG490 could suppress bone marrow mesenchymal stem cells migration, mineralization and bone defect healing via inhibiting Jak2-STAT3 pathway].
    Yu X; Wan QL; Li Z; Li ZB
    Zhonghua Kou Qiang Yi Xue Za Zhi; 2018 May; 53(5):293-300. PubMed ID: 29972985
    [No Abstract]   [Full Text] [Related]  

  • 10. Swelling-induced chloride current in glioblastoma proliferation, migration, and invasion.
    Wong R; Chen W; Zhong X; Rutka JT; Feng ZP; Sun HS
    J Cell Physiol; 2018 Jan; 233(1):363-370. PubMed ID: 28262948
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tetraarsenic oxide-induced inhibition of malignant glioma cell invasion in vitro via a decrease in matrix metalloproteinase secretion and protein kinase B phosphorylation.
    Gwak HS; Park MJ; Park IC; Woo SH; Jin HO; Rhee CH; Jung HW
    J Neurosurg; 2014 Dec; 121(6):1483-91. PubMed ID: 25303017
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of the JAK2/STAT3 inhibitor SAR317461 on human glioblastoma tumorspheres.
    Mukthavaram R; Ouyang X; Saklecha R; Jiang P; Nomura N; Pingle SC; Guo F; Makale M; Kesari S
    J Transl Med; 2015 Aug; 13():269. PubMed ID: 26283544
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Jak2 small molecule inhibitor, G6, reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo.
    Baskin R; Park SO; Keserű GM; Bisht KS; Wamsley HL; Sayeski PP
    PLoS One; 2014; 9(8):e105568. PubMed ID: 25162558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Effect of AG490 on JAK2/STAT3 signaling pathway in human retinoblastoma HXO-RB44 cell lines].
    Xu B; Chen X; Tan J; Xu X
    Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2018 Oct; 43(10):1061-1067. PubMed ID: 30523225
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of autophagy biomarker BNIP3 requires a JAK2/STAT3 and MT1-MMP signaling interplay in Concanavalin-A-activated U87 glioblastoma cells.
    Pratt J; Annabi B
    Cell Signal; 2014 May; 26(5):917-24. PubMed ID: 24462646
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma.
    Ashizawa T; Miyata H; Iizuka A; Komiyama M; Oshita C; Kume A; Nogami M; Yagoto M; Ito I; Oishi T; Watanabe R; Mitsuya K; Matsuno K; Furuya T; Okawara T; Otsuka M; Ogo N; Asai A; Nakasu Y; Yamaguchi K; Akiyama Y
    Int J Oncol; 2013 Jul; 43(1):219-27. PubMed ID: 23612755
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anlotinib combined with temozolomide suppresses glioblastoma growth via mediation of JAK2/STAT3 signaling pathway.
    Xu P; Wang H; Pan H; Chen J; Deng C
    Cancer Chemother Pharmacol; 2022 Feb; 89(2):183-196. PubMed ID: 34997858
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1.
    Li R; Li G; Deng L; Liu Q; Dai J; Shen J; Zhang J
    Oncol Rep; 2010 Jun; 23(6):1553-9. PubMed ID: 20428809
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ascochlorin Suppresses MMP-2-Mediated Migration and Invasion by Targeting FAK and JAK-STAT Signaling Cascades.
    Cho HJ; Park JH; Nam JH; Chang YC; Park B; Hoe HS
    J Cell Biochem; 2018 Jan; 119(1):300-313. PubMed ID: 28569433
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High mobility group box 1 induces the activation of the Janus kinase 2 and signal transducer and activator of transcription 3 (JAK2/STAT3) signaling pathway in pancreatic acinar cells in rats, while AG490 and rapamycin inhibit their activation.
    Wang G; Zhang J; Dui D; Ren H; Liu J
    Bosn J Basic Med Sci; 2016 Nov; 16(4):307-312. PubMed ID: 27754827
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.