274 related articles for article (PubMed ID: 20590641)
1. Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.
Desaphy JF; Dipalma A; Costanza T; Bruno C; Lentini G; Franchini C; George A; Conte Camerino D
Br J Pharmacol; 2010 Jul; 160(6):1521-33. PubMed ID: 20590641
[TBL] [Abstract][Full Text] [Related]
2. Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block.
Desaphy JF; De Luca A; Didonna MP; George AL; Camerino Conte D
J Physiol; 2004 Jan; 554(Pt 2):321-34. PubMed ID: 14608015
[TBL] [Abstract][Full Text] [Related]
3. Mexiletine block of wild-type and inactivation-deficient human skeletal muscle hNav1.4 Na+ channels.
Wang GK; Russell C; Wang SY
J Physiol; 2004 Feb; 554(Pt 3):621-33. PubMed ID: 14608007
[TBL] [Abstract][Full Text] [Related]
4. State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.
Wang GK; Calderon J; Wang SY
Mol Pharmacol; 2008 Mar; 73(3):940-8. PubMed ID: 18079277
[TBL] [Abstract][Full Text] [Related]
5. Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues.
Liu H; Atkins J; Kass RS
J Gen Physiol; 2003 Mar; 121(3):199-214. PubMed ID: 12601084
[TBL] [Abstract][Full Text] [Related]
6. Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo.
Desaphy JF; Farinato A; Altamura C; De Bellis M; Imbrici P; Tarantino N; Caccia C; Melloni E; Padoani G; Vailati S; Keywood C; Carratù MR; De Luca A; Conte D; Pierno S
Exp Neurol; 2020 Jun; 328():113287. PubMed ID: 32205118
[TBL] [Abstract][Full Text] [Related]
7. Comparison of Gating Properties and Use-Dependent Block of Nav1.5 and Nav1.7 Channels by Anti-Arrhythmics Mexiletine and Lidocaine.
Wang Y; Mi J; Lu K; Lu Y; Wang K
PLoS One; 2015; 10(6):e0128653. PubMed ID: 26068619
[TBL] [Abstract][Full Text] [Related]
8. Effects of Na+ channel blocker, pilsicainide, on HERG current expressed in HEK-293 cells.
Wu LM; Orikabe M; Hirano Y; Kawano S; Hiraoka M
J Cardiovasc Pharmacol; 2003 Sep; 42(3):410-8. PubMed ID: 12960687
[TBL] [Abstract][Full Text] [Related]
9. Molecular dissection of lubeluzole use-dependent block of voltage-gated sodium channels discloses new therapeutic potentials.
Desaphy JF; Carbonara R; Costanza T; Lentini G; Cavalluzzi MM; Bruno C; Franchini C; Camerino DC
Mol Pharmacol; 2013 Feb; 83(2):406-15. PubMed ID: 23175529
[TBL] [Abstract][Full Text] [Related]
10. Translation of flecainide- and mexiletine-induced cardiac sodium channel inhibition and ventricular conduction slowing from nonclinical models to clinical.
Heath BM; Cui Y; Worton S; Lawton B; Ward G; Ballini E; Doe CP; Ellis C; Patel BA; McMahon NC
J Pharmacol Toxicol Methods; 2011; 63(3):258-68. PubMed ID: 21194571
[TBL] [Abstract][Full Text] [Related]
11. Assessing use-dependent inhibition of the cardiac Na(+/-) current (I(Na)) in the PatchXpress automated patch clamp.
Penniman JR; Kim DC; Salata JJ; Imredy JP
J Pharmacol Toxicol Methods; 2010; 62(2):107-18. PubMed ID: 20601018
[TBL] [Abstract][Full Text] [Related]
12. Class Ic antiarrhythmics block human skeletal muscle Na channel during myotonia-like stimulation.
Aoike F; Takahashi MP; Sakoda S
Eur J Pharmacol; 2006 Feb; 532(1-2):24-31. PubMed ID: 16473348
[TBL] [Abstract][Full Text] [Related]
13. State-dependent trapping of flecainide in the cardiac sodium channel.
Ramos E; O'leary ME
J Physiol; 2004 Oct; 560(Pt 1):37-49. PubMed ID: 15272045
[TBL] [Abstract][Full Text] [Related]
14. A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity.
Sheets PL; Jackson JO; Waxman SG; Dib-Hajj SD; Cummins TR
J Physiol; 2007 Jun; 581(Pt 3):1019-31. PubMed ID: 17430993
[TBL] [Abstract][Full Text] [Related]
15. Comparison of the effects of four Na+ channel analgesics on TTX-resistant Na+ currents in rat sensory neurons and recombinant Nav1.2 channels.
Weiser T
Neurosci Lett; 2006 Mar; 395(3):179-84. PubMed ID: 16293367
[TBL] [Abstract][Full Text] [Related]
16. Inactivation-deficient human skeletal muscle Na+ channels (hNav1.4-L443C/A444W) in stably transfected HEK-293 cells.
Wang SY; Moczydlowski E; Wang G
Recept Channels; 2004; 10(3-4):131-8. PubMed ID: 15512848
[TBL] [Abstract][Full Text] [Related]
17. Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels.
Sheets MF; Hanck DA
J Physiol; 2007 Jul; 582(Pt 1):317-34. PubMed ID: 17510181
[TBL] [Abstract][Full Text] [Related]
18. State-dependent block of human cardiac hNav1.5 sodium channels by propafenone.
Edrich T; Wang SY; Wang GK
J Membr Biol; 2005 Sep; 207(1):35-43. PubMed ID: 16463141
[TBL] [Abstract][Full Text] [Related]
19. Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity.
Hanck DA; Nikitina E; McNulty MM; Fozzard HA; Lipkind GM; Sheets MF
Circ Res; 2009 Aug; 105(5):492-9. PubMed ID: 19661462
[TBL] [Abstract][Full Text] [Related]
20. Gating of myotonic Na channel mutants defines the response to mexiletine and a potent derivative.
Desaphy JF; De Luca A; Tortorella P; De Vito D; George AL; Conte Camerino D
Neurology; 2001 Nov; 57(10):1849-57. PubMed ID: 11723275
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]