These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 20592017)

  • 1. MDM2 mediates ubiquitination and degradation of activating transcription factor 3.
    Mo P; Wang H; Lu H; Boyd DD; Yan C
    J Biol Chem; 2010 Aug; 285(35):26908-26915. PubMed ID: 20592017
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Competitive ubiquitination activates the tumor suppressor p53.
    Li X; Guo M; Cai L; Du T; Liu Y; Ding HF; Wang H; Zhang J; Chen X; Yan C
    Cell Death Differ; 2020 Jun; 27(6):1807-1818. PubMed ID: 31796886
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6.
    Wang H; Mo P; Ren S; Yan C
    J Biol Chem; 2010 Apr; 285(17):13201-10. PubMed ID: 20167600
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7.
    Zhao K; Yang Y; Zhang G; Wang C; Wang D; Wu M; Mei Y
    EMBO Rep; 2018 Feb; 19(2):305-319. PubMed ID: 29295817
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response.
    Lim KH; Park JJ; Gu BH; Kim JO; Park SG; Baek KH
    Sci Rep; 2015 Aug; 5():12793. PubMed ID: 26238070
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination.
    Yan C; Lu D; Hai T; Boyd DD
    EMBO J; 2005 Jul; 24(13):2425-35. PubMed ID: 15933712
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation.
    Ghosh M; Huang K; Berberich SJ
    Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage.
    Fu X; Yucer N; Liu S; Li M; Yi P; Mu JJ; Yang T; Chu J; Jung SY; O'Malley BW; Gu W; Qin J; Wang Y
    Proc Natl Acad Sci U S A; 2010 Mar; 107(10):4579-84. PubMed ID: 20173098
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.
    Lindström MS; Jin A; Deisenroth C; White Wolf G; Zhang Y
    Mol Cell Biol; 2007 Feb; 27(3):1056-68. PubMed ID: 17116689
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A second p53 binding site in the central domain of Mdm2 is essential for p53 ubiquitination.
    Ma J; Martin JD; Zhang H; Auger KR; Ho TF; Kirkpatrick RB; Grooms MH; Johanson KO; Tummino PJ; Copeland RA; Lai Z
    Biochemistry; 2006 Aug; 45(30):9238-45. PubMed ID: 16866370
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation.
    Bae S; Jung JH; Kim K; An IS; Kim SY; Lee JH; Park IC; Jin YW; Lee SJ; An S
    FEBS Lett; 2012 Sep; 586(19):3057-63. PubMed ID: 22819825
    [TBL] [Abstract][Full Text] [Related]  

  • 12. miR-498 inhibits autophagy and M2-like polarization of tumor-associated macrophages in esophageal cancer via MDM2/ATF3.
    Li D; Yan M; Sun F; Song J; Hu X; Yu S; Tang L; Deng S
    Epigenomics; 2021 Jul; 13(13):1013-1030. PubMed ID: 34114479
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autoactivation of the MDM2 E3 ligase by intramolecular interaction.
    Cheng Q; Song T; Chen L; Chen J
    Mol Cell Biol; 2014 Aug; 34(15):2800-10. PubMed ID: 24842904
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unlocking the Mdm2-p53 loop: ubiquitin is the key.
    Clegg HV; Itahana K; Zhang Y
    Cell Cycle; 2008 Feb; 7(3):287-92. PubMed ID: 18235222
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation.
    Fu W; Ma Q; Chen L; Li P; Zhang M; Ramamoorthy S; Nawaz Z; Shimojima T; Wang H; Yang Y; Shen Z; Zhang Y; Zhang X; Nicosia SV; Zhang Y; Pledger JW; Chen J; Bai W
    J Biol Chem; 2009 May; 284(21):13987-4000. PubMed ID: 19321440
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53.
    Fang S; Jensen JP; Ludwig RL; Vousden KH; Weissman AM
    J Biol Chem; 2000 Mar; 275(12):8945-51. PubMed ID: 10722742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SUMOylation of ATF3 alters its transcriptional activity on regulation of TP53 gene.
    Wang CM; Brennan VC; Gutierrez NM; Wang X; Wang L; Yang WH
    J Cell Biochem; 2013 Mar; 114(3):589-98. PubMed ID: 22991139
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant p53 Sequestration of the MDM2 Acidic Domain Inhibits E3 Ligase Activity.
    Yang L; Song T; Cheng Q; Chen L; Chen J
    Mol Cell Biol; 2019 Feb; 39(4):. PubMed ID: 30455251
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of MDM2 E3 ligase activity by phosphorylation after DNA damage.
    Cheng Q; Cross B; Li B; Chen L; Li Z; Chen J
    Mol Cell Biol; 2011 Dec; 31(24):4951-63. PubMed ID: 21986495
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.
    Nihira NT; Ogura K; Shimizu K; North BJ; Zhang J; Gao D; Inuzuka H; Wei W
    Sci Signal; 2017 Feb; 10(466):. PubMed ID: 28196907
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.