These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 20595278)

  • 1. 677TT genotype is associated with elevated risk of methotrexate (MTX) toxicity in juvenile idiopathic arthritis: treatment outcome, erythrocyte concentrations of MTX and folates, and MTHFR polymorphisms.
    Tuková J; Chládek J; Hroch M; Nemcová D; Hoza J; Dolezalová P
    J Rheumatol; 2010 Oct; 37(10):2180-6. PubMed ID: 20595278
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
    Schmeling H; Biber D; Heins S; Horneff G
    J Rheumatol; 2005 Sep; 32(9):1832-6. PubMed ID: 16142884
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response.
    Becker ML; Gaedigk R; van Haandel L; Thomas B; Lasky A; Hoeltzel M; Dai H; Stobaugh J; Leeder JS
    Arthritis Rheum; 2011 Jan; 63(1):276-85. PubMed ID: 20954192
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene.
    Berkun Y; Levartovsky D; Rubinow A; Orbach H; Aamar S; Grenader T; Abou Atta I; Mevorach D; Friedman G; Ben-Yehuda A
    Ann Rheum Dis; 2004 Oct; 63(10):1227-31. PubMed ID: 15361376
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population.
    Cáliz R; del Amo J; Balsa A; Blanco F; Silva L; Sanmarti R; Martínez FG; Collado MD; Ramirez Mdel C; Tejedor D; Artieda M; Pascual-Salcedo D; Oreiro N; Andreu JL; Graell E; Simon L; Martínez A; Mulero J
    Scand J Rheumatol; 2012 Feb; 41(1):10-4. PubMed ID: 22044028
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
    Wessels JA; de Vries-Bouwstra JK; Heijmans BT; Slagboom PE; Goekoop-Ruiterman YP; Allaart CF; Kerstens PJ; van Zeben D; Breedveld FC; Dijkmans BA; Huizinga TW; Guchelaar HJ
    Arthritis Rheum; 2006 Apr; 54(4):1087-95. PubMed ID: 16572443
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Adenosine and methotrexate polyglutamate concentrations in patients with juvenile arthritis.
    Dolezalová P; Krijt J; Chládek J; Nemcová D; Hoza J
    Rheumatology (Oxford); 2005 Jan; 44(1):74-9. PubMed ID: 15454631
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Correlation between methotrexate efficacy & toxicity with C677T polymorphism of the methylenetetrahydrofolate gene in rheumatoid arthritis patients on folate supplementation.
    Aggarwal P; Naik S; Mishra KP; Aggarwal A; Misra R
    Indian J Med Res; 2006 Nov; 124(5):521-6. PubMed ID: 17213520
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.
    Kumagai K; Hiyama K; Oyama T; Maeda H; Kohno N
    Int J Mol Med; 2003 May; 11(5):593-600. PubMed ID: 12684695
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate.
    Kim SK; Jun JB; El-Sohemy A; Bae SC
    J Rheumatol; 2006 Jul; 33(7):1266-74. PubMed ID: 16758511
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional variants of gene encoding folate metabolizing enzyme and methotrexate-related toxicity in children with acute lymphoblastic leukemia.
    Kałużna E; Strauss E; Zając-Spychała O; Gowin E; Świątek-Kościelna B; Nowak J; Fichna M; Mańkowski P; Januszkiewicz-Lewandowska D
    Eur J Pharmacol; 2015 Dec; 769():93-9. PubMed ID: 26528799
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Methotrexate toxicity and efficacy during the consolidation phase in paediatric acute lymphoblastic leukaemia and MTHFR polymorphisms as pharmacogenetic determinants.
    D'Angelo V; Ramaglia M; Iannotta A; Crisci S; Indolfi P; Francese M; Affinita MC; Pecoraro G; Napolitano A; Fusco C; Oreste M; Indolfi C; Casale F
    Cancer Chemother Pharmacol; 2011 Nov; 68(5):1339-46. PubMed ID: 21590445
    [TBL] [Abstract][Full Text] [Related]  

  • 13. C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: effect on methotrexate-related toxicity in adult acute lymphoblastic leukaemia.
    Eissa DS; Ahmed TM
    Blood Coagul Fibrinolysis; 2013 Mar; 24(2):181-8. PubMed ID: 23183238
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methylene tetrahydrofolate reductase genotypes frequencies: association with toxicity and response to methotrexate in rheumatoid arthritis patients.
    Saleh MM; Irshaid YM; Mustafa KN
    Int J Clin Pharmacol Ther; 2015 Feb; 53(2):154-62. PubMed ID: 25492850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients.
    Chiusolo P; Reddiconto G; Farina G; Mannocci A; Fiorini A; Palladino M; La Torre G; Fianchi L; Sorà F; Laurenti L; Leone G; Sica S
    Leuk Res; 2007 Dec; 31(12):1669-74. PubMed ID: 17512587
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: implication with elevation of transaminases.
    Mena JP; Salazar-Páramo M; González-López L; Gámez-Nava JI; Sandoval-Ramirez L; Sánchez JD; Figuera LE; Muñoz-Valle FJ; Vazquez del Mercado M; Dávalos IP
    Pharmacogenomics J; 2011 Aug; 11(4):287-91. PubMed ID: 20514079
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Polymorphisms of the methylenetetrahydrofolate reductase gene and clinical outcomes in HLA-matched sibling allogeneic hematopoietic stem cell transplantation.
    Kim I; Lee KH; Kim JH; Ra EK; Yoon SS; Hong YC; Park SS; Kim CS; Park S; Kim BK
    Ann Hematol; 2007 Jan; 86(1):41-8. PubMed ID: 17028897
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate.
    Stamp LK; Chapman PT; O'Donnell JL; Zhang M; James J; Frampton C; Barclay ML; Kennedy MA; Roberts RL
    Pharmacogenet Genomics; 2010 Jun; 20(6):367-76. PubMed ID: 20386493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of intracellular methotrexate polyglutamates in patients with juvenile idiopathic arthritis: effect of route of administration on variability in intracellular methotrexate polyglutamate concentrations.
    Becker ML; van Haandel L; Gaedigk R; Lasky A; Hoeltzel M; Stobaugh J; Leeder JS
    Arthritis Rheum; 2010 Jun; 62(6):1803-12. PubMed ID: 20191581
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms.
    Owen SA; Lunt M; Bowes J; Hider SL; Bruce IN; Thomson W; Barton A
    Pharmacogenomics J; 2013 Apr; 13(2):137-47. PubMed ID: 21931346
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.