285 related articles for article (PubMed ID: 20595388)
1. Calpain activation promotes BACE1 expression, amyloid precursor protein processing, and amyloid plaque formation in a transgenic mouse model of Alzheimer disease.
Liang B; Duan BY; Zhou XP; Gong JX; Luo ZG
J Biol Chem; 2010 Sep; 285(36):27737-44. PubMed ID: 20595388
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.
Ly PT; Wu Y; Zou H; Wang R; Zhou W; Kinoshita A; Zhang M; Yang Y; Cai F; Woodgett J; Song W
J Clin Invest; 2013 Jan; 123(1):224-35. PubMed ID: 23202730
[TBL] [Abstract][Full Text] [Related]
3. Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice.
Leroy K; Ando K; Laporte V; Dedecker R; Suain V; Authelet M; Héraud C; Pierrot N; Yilmaz Z; Octave JN; Brion JP
Am J Pathol; 2012 Dec; 181(6):1928-40. PubMed ID: 23026200
[TBL] [Abstract][Full Text] [Related]
4. BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer's disease: differential Aβ antibody labeling of early-onset axon terminal pathology.
Cai Y; Zhang XM; Macklin LN; Cai H; Luo XG; Oddo S; Laferla FM; Struble RG; Rose GM; Patrylo PR; Yan XX
Neurotox Res; 2012 Feb; 21(2):160-74. PubMed ID: 21725719
[TBL] [Abstract][Full Text] [Related]
5. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
6. Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD mice.
Yan XX; Cai Y; Shelton J; Deng SH; Luo XG; Oddo S; Laferla FM; Cai H; Rose GM; Patrylo PR
PLoS One; 2012; 7(11):e48782. PubMed ID: 23155407
[TBL] [Abstract][Full Text] [Related]
7. Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice.
McConlogue L; Buttini M; Anderson JP; Brigham EF; Chen KS; Freedman SB; Games D; Johnson-Wood K; Lee M; Zeller M; Liu W; Motter R; Sinha S
J Biol Chem; 2007 Sep; 282(36):26326-34. PubMed ID: 17616527
[TBL] [Abstract][Full Text] [Related]
8. Berberine Alleviates Amyloid-Beta Pathology in the Brain of APP/PS1 Transgenic Mice via Inhibiting β/γ-Secretases Activity and Enhancing α-Secretases.
Cai Z; Wang C; He W; Chen Y
Curr Alzheimer Res; 2018; 15(11):1045-1052. PubMed ID: 29962345
[TBL] [Abstract][Full Text] [Related]
9. GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.
Tian J; Shi J; Zhang L; Yin J; Hu Q; Xu Y; Sheng S; Wang P; Ren Y; Wang R; Wang Y
Curr Alzheimer Res; 2009 Apr; 6(2):118-31. PubMed ID: 19355846
[TBL] [Abstract][Full Text] [Related]
10. Mechanistic involvement of the calpain-calpastatin system in Alzheimer neuropathology.
Higuchi M; Iwata N; Matsuba Y; Takano J; Suemoto T; Maeda J; Ji B; Ono M; Staufenbiel M; Suhara T; Saido TC
FASEB J; 2012 Mar; 26(3):1204-17. PubMed ID: 22173972
[TBL] [Abstract][Full Text] [Related]
11. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
Sakae N; Liu CC; Shinohara M; Frisch-Daiello J; Ma L; Yamazaki Y; Tachibana M; Younkin L; Kurti A; Carrasquillo MM; Zou F; Sevlever D; Bisceglio G; Gan M; Fol R; Knight P; Wang M; Han X; Fryer JD; Fitzgerald ML; Ohyagi Y; Younkin SG; Bu G; Kanekiyo T
J Neurosci; 2016 Mar; 36(13):3848-59. PubMed ID: 27030769
[TBL] [Abstract][Full Text] [Related]
12. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
[TBL] [Abstract][Full Text] [Related]
13. Histone acetyltransferase p300 mediates histone acetylation of PS1 and BACE1 in a cellular model of Alzheimer's disease.
Lu X; Deng Y; Yu D; Cao H; Wang L; Liu L; Yu C; Zhang Y; Guo X; Yu G
PLoS One; 2014; 9(7):e103067. PubMed ID: 25051175
[TBL] [Abstract][Full Text] [Related]
14. Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice.
Saura CA; Chen G; Malkani S; Choi SY; Takahashi RH; Zhang D; Gouras GK; Kirkwood A; Morris RG; Shen J
J Neurosci; 2005 Jul; 25(29):6755-64. PubMed ID: 16033885
[TBL] [Abstract][Full Text] [Related]
15. Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice.
Kimura R; Devi L; Ohno M
J Neurochem; 2010 Apr; 113(1):248-61. PubMed ID: 20089133
[TBL] [Abstract][Full Text] [Related]
16. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
O'Connor T; Sadleir KR; Maus E; Velliquette RA; Zhao J; Cole SL; Eimer WA; Hitt B; Bembinster LA; Lammich S; Lichtenthaler SF; Hébert SS; De Strooper B; Haass C; Bennett DA; Vassar R
Neuron; 2008 Dec; 60(6):988-1009. PubMed ID: 19109907
[TBL] [Abstract][Full Text] [Related]
17. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
18. APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease.
Barbero-Camps E; Fernández A; Martínez L; Fernández-Checa JC; Colell A
Hum Mol Genet; 2013 Sep; 22(17):3460-76. PubMed ID: 23648430
[TBL] [Abstract][Full Text] [Related]
19. Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease.
Aso E; Lomoio S; López-González I; Joda L; Carmona M; Fernández-Yagüe N; Moreno J; Juvés S; Pujol A; Pamplona R; Portero-Otin M; Martín V; Díaz M; Ferrer I
Brain Pathol; 2012 Sep; 22(5):636-53. PubMed ID: 22188425
[TBL] [Abstract][Full Text] [Related]
20. [Effects of huannao yicong recipe extract on the learning and memory and related factors of Abeta generation in the brain of APP transgenic mice].
Li H; Liu MF; Liu JG; Liu LT; Guan J; Cai LL; Hu J; Wei Y
Zhongguo Zhong Xi Yi Jie He Za Zhi; 2013 Jan; 33(1):90-4. PubMed ID: 23596795
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
