BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 20599567)

  • 1. A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage.
    Carlessi L; Buscemi G; Fontanella E; Delia D
    Biochim Biophys Acta; 2010 Oct; 1803(10):1213-23. PubMed ID: 20599567
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein phosphatase 2A interacts with Chk2 and regulates phosphorylation at Thr-68 after cisplatin treatment of human ovarian cancer cells.
    Liang X; Reed E; Yu JJ
    Int J Mol Med; 2006 May; 17(5):703-8. PubMed ID: 16596250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase.
    Fujimoto H; Onishi N; Kato N; Takekawa M; Xu XZ; Kosugi A; Kondo T; Imamura M; Oishi I; Yoda A; Minami Y
    Cell Death Differ; 2006 Jul; 13(7):1170-80. PubMed ID: 16311512
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.
    Yoda A; Toyoshima K; Watanabe Y; Onishi N; Hazaka Y; Tsukuda Y; Tsukada J; Kondo T; Tanaka Y; Minami Y
    J Biol Chem; 2008 Jul; 283(27):18969-79. PubMed ID: 18482988
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
    Oliva-Trastoy M; Berthonaud V; Chevalier A; Ducrot C; Marsolier-Kergoat MC; Mann C; Leteurtre F
    Oncogene; 2007 Mar; 26(10):1449-58. PubMed ID: 16936775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage.
    Bahassi el M; Myer DL; McKenney RJ; Hennigan RF; Stambrook PJ
    Mutat Res; 2006 Apr; 596(1-2):166-76. PubMed ID: 16481012
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.
    Goodarzi AA; Jonnalagadda JC; Douglas P; Young D; Ye R; Moorhead GB; Lees-Miller SP; Khanna KK
    EMBO J; 2004 Nov; 23(22):4451-61. PubMed ID: 15510216
    [TBL] [Abstract][Full Text] [Related]  

  • 8. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.
    Townsend PA; Cragg MS; Davidson SM; McCormick J; Barry S; Lawrence KM; Knight RA; Hubank M; Chen PL; Latchman DS; Stephanou A
    J Cell Sci; 2005 Apr; 118(Pt 8):1629-39. PubMed ID: 15784679
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2.
    Carlessi L; Buscemi G; Larson G; Hong Z; Wu JZ; Delia D
    Mol Cancer Ther; 2007 Mar; 6(3):935-44. PubMed ID: 17363488
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylation of p53 on Ser15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation.
    Zhao H; Traganos F; Darzynkiewicz Z
    Cell Cycle; 2008 Oct; 7(19):3048-55. PubMed ID: 18802408
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Utilizing protein phosphatase inhibitors to define PP2A as a regulator of ataxia-telangiectasia mutated.
    Goodarzi AA; Douglas P; Moorhead GB; Lees-Miller SP
    Methods Mol Biol; 2007; 365():47-59. PubMed ID: 17200553
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint.
    Petersen P; Chou DM; You Z; Hunter T; Walter JC; Walter G
    Mol Cell Biol; 2006 Mar; 26(5):1997-2011. PubMed ID: 16479016
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation.
    Wei F; Xie Y; Tao L; Tang D
    Cell Signal; 2010 Nov; 22(11):1783-9. PubMed ID: 20637859
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Wip1 phosphatase modulates ATM-dependent signaling pathways.
    Shreeram S; Demidov ON; Hee WK; Yamaguchi H; Onishi N; Kek C; Timofeev ON; Dudgeon C; Fornace AJ; Anderson CW; Minami Y; Appella E; Bulavin DV
    Mol Cell; 2006 Sep; 23(5):757-64. PubMed ID: 16949371
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest.
    Yong W; Bao S; Chen H; Li D; Sánchez ER; Shou W
    J Biol Chem; 2007 May; 282(20):14690-4. PubMed ID: 17376776
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relationship between ATM and ribosomal protein S6 revealed by the chemical inhibition of Ser/Thr protein phosphatase type 1.
    Li Y; Mitsuhashi S; Ikejo M; Miura N; Kawamura T; Hamakubo T; Ubukata M
    Biosci Biotechnol Biochem; 2012; 76(3):486-94. PubMed ID: 22451389
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways.
    Solier S; Sordet O; Kohn KW; Pommier Y
    Mol Cell Biol; 2009 Jan; 29(1):68-82. PubMed ID: 18955500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues.
    Buscemi G; Carlessi L; Zannini L; Lisanti S; Fontanella E; Canevari S; Delia D
    Mol Cell Biol; 2006 Nov; 26(21):7832-45. PubMed ID: 16940182
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
    Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
    EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway.
    Chaturvedi P; Eng WK; Zhu Y; Mattern MR; Mishra R; Hurle MR; Zhang X; Annan RS; Lu Q; Faucette LF; Scott GF; Li X; Carr SA; Johnson RK; Winkler JD; Zhou BB
    Oncogene; 1999 Jul; 18(28):4047-54. PubMed ID: 10435585
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.