211 related articles for article (PubMed ID: 20601443)
1. Influence of Oct1/Oct2-deficiency on cisplatin-induced changes in urinary N-acetyl-beta-D-glucosaminidase.
Franke RM; Kosloske AM; Lancaster CS; Filipski KK; Hu C; Zolk O; Mathijssen RH; Sparreboom A
Clin Cancer Res; 2010 Aug; 16(16):4198-206. PubMed ID: 20601443
[TBL] [Abstract][Full Text] [Related]
2. Cisplatin-induced renal injury is independently mediated by OCT2 and p53.
Sprowl JA; Lancaster CS; Pabla N; Hermann E; Kosloske AM; Gibson AA; Li L; Zeeh D; Schlatter E; Janke LJ; Ciarimboli G; Sparreboom A
Clin Cancer Res; 2014 Aug; 20(15):4026-35. PubMed ID: 24916697
[TBL] [Abstract][Full Text] [Related]
3. Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity.
Filipski KK; Mathijssen RH; Mikkelsen TS; Schinkel AH; Sparreboom A
Clin Pharmacol Ther; 2009 Oct; 86(4):396-402. PubMed ID: 19625999
[TBL] [Abstract][Full Text] [Related]
4. Ablation of both organic cation transporter (OCT)1 and OCT2 alters metformin pharmacokinetics but has no effect on tissue drug exposure and pharmacodynamics.
Higgins JW; Bedwell DW; Zamek-Gliszczynski MJ
Drug Metab Dispos; 2012 Jun; 40(6):1170-7. PubMed ID: 22407892
[TBL] [Abstract][Full Text] [Related]
5. Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions.
Ciarimboli G; Deuster D; Knief A; Sperling M; Holtkamp M; Edemir B; Pavenstädt H; Lanvers-Kaminsky C; am Zehnhoff-Dinnesen A; Schinkel AH; Koepsell H; Jürgens H; Schlatter E
Am J Pathol; 2010 Mar; 176(3):1169-80. PubMed ID: 20110413
[TBL] [Abstract][Full Text] [Related]
6. Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs).
Li Q; Guo D; Dong Z; Zhang W; Zhang L; Huang SM; Polli JE; Shu Y
Toxicol Appl Pharmacol; 2013 Nov; 273(1):100-9. PubMed ID: 24001450
[TBL] [Abstract][Full Text] [Related]
7. Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity.
Yokoo S; Yonezawa A; Masuda S; Fukatsu A; Katsura T; Inui K
Biochem Pharmacol; 2007 Aug; 74(3):477-87. PubMed ID: 17582384
[TBL] [Abstract][Full Text] [Related]
8. Cisplatin-induced downregulation of OCTN2 affects carnitine wasting.
Lancaster CS; Hu C; Franke RM; Filipski KK; Orwick SJ; Chen Z; Zuo Z; Loos WJ; Sparreboom A
Clin Cancer Res; 2010 Oct; 16(19):4789-99. PubMed ID: 20858838
[TBL] [Abstract][Full Text] [Related]
9. Selective Inhibition on Organic Cation Transporters by Carvedilol Protects Mice from Cisplatin-Induced Nephrotoxicity.
Guo D; Yang H; Li Q; Bae HJ; Obianom O; Zeng S; Su T; Polli JE; Shu Y
Pharm Res; 2018 Sep; 35(11):204. PubMed ID: 30191328
[TBL] [Abstract][Full Text] [Related]
10. Conjunctive therapy of cisplatin with the OCT2 inhibitor cimetidine: influence on antitumor efficacy and systemic clearance.
Sprowl JA; van Doorn L; Hu S; van Gerven L; de Bruijn P; Li L; Gibson AA; Mathijssen RH; Sparreboom A
Clin Pharmacol Ther; 2013 Nov; 94(5):585-92. PubMed ID: 23863876
[TBL] [Abstract][Full Text] [Related]
11. Proximal tubular secretion of creatinine by organic cation transporter OCT2 in cancer patients.
Ciarimboli G; Lancaster CS; Schlatter E; Franke RM; Sprowl JA; Pavenstädt H; Massmann V; Guckel D; Mathijssen RH; Yang W; Pui CH; Relling MV; Herrmann E; Sparreboom A
Clin Cancer Res; 2012 Feb; 18(4):1101-8. PubMed ID: 22223530
[TBL] [Abstract][Full Text] [Related]
12. Decreased expression of organic cation transporters, Oct1 and Oct2, in brain microvessels and its implication to MPTP-induced dopaminergic toxicity in aged mice.
Wu KC; Lu YH; Peng YH; Tsai TF; Kao YH; Yang HT; Lin CJ
J Cereb Blood Flow Metab; 2015 Jan; 35(1):37-47. PubMed ID: 25248837
[TBL] [Abstract][Full Text] [Related]
13. Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations.
Jonker JW; Wagenaar E; Van Eijl S; Schinkel AH
Mol Cell Biol; 2003 Nov; 23(21):7902-8. PubMed ID: 14560032
[TBL] [Abstract][Full Text] [Related]
14. Pantoprazole, an Inhibitor of the Organic Cation Transporter 2, Does Not Ameliorate Cisplatin-Related Ototoxicity or Nephrotoxicity in Children and Adolescents with Newly Diagnosed Osteosarcoma Treated with Methotrexate, Doxorubicin, and Cisplatin.
Fox E; Levin K; Zhu Y; Segers B; Balamuth N; Womer R; Bagatell R; Balis F
Oncologist; 2018 Jul; 23(7):762-e79. PubMed ID: 29445029
[TBL] [Abstract][Full Text] [Related]
15. Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity.
Nakamura T; Yonezawa A; Hashimoto S; Katsura T; Inui K
Biochem Pharmacol; 2010 Dec; 80(11):1762-7. PubMed ID: 20813096
[TBL] [Abstract][Full Text] [Related]
16. The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity.
Pabla N; Murphy RF; Liu K; Dong Z
Am J Physiol Renal Physiol; 2009 Mar; 296(3):F505-11. PubMed ID: 19144690
[TBL] [Abstract][Full Text] [Related]
17. Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of Cisplatin.
Mody H; Vaidya TR; Lesko LJ; Ait-Oudhia S
Cells; 2022 Dec; 12(1):. PubMed ID: 36611850
[TBL] [Abstract][Full Text] [Related]
18. Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.
Urakami Y; Okuda M; Masuda S; Saito H; Inui KI
J Pharmacol Exp Ther; 1998 Nov; 287(2):800-5. PubMed ID: 9808712
[TBL] [Abstract][Full Text] [Related]
19. Functional mapping of rbOCT1 and rbOCT2 activity in the S2 segment of rabbit proximal tubule.
Kaewmokul S; Chatsudthipong V; Evans KK; Dantzler WH; Wright SH
Am J Physiol Renal Physiol; 2003 Dec; 285(6):F1149-59. PubMed ID: 12944320
[TBL] [Abstract][Full Text] [Related]
20. [Platinum agent-induced nephrotoxicity via organic cation transport system].
Yonezawa A
Yakugaku Zasshi; 2012; 132(11):1281-5. PubMed ID: 23123720
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
