BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

719 related articles for article (PubMed ID: 20601939)

  • 1. Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.
    Holt N; Wang J; Kim K; Friedman G; Wang X; Taupin V; Crooks GM; Kohn DB; Gregory PD; Holmes MC; Cannon PM
    Nat Biotechnol; 2010 Aug; 28(8):839-47. PubMed ID: 20601939
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases.
    Li L; Krymskaya L; Wang J; Henley J; Rao A; Cao LF; Tran CA; Torres-Coronado M; Gardner A; Gonzalez N; Kim K; Liu PQ; Hofer U; Lopez E; Gregory PD; Liu Q; Holmes MC; Cannon PM; Zaia JA; DiGiusto DL
    Mol Ther; 2013 Jun; 21(6):1259-69. PubMed ID: 23587921
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice.
    Hofer U; Henley JE; Exline CM; Mulhern O; Lopez E; Cannon PM
    J Infect Dis; 2013 Nov; 208 Suppl 2(Suppl 2):S160-4. PubMed ID: 24151324
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice.
    Ringpis GE; Shimizu S; Arokium H; Camba-Colón J; Carroll MV; Cortado R; Xie Y; Kim PY; Sahakyan A; Lowe EL; Narukawa M; Kandarian FN; Burke BP; Symonds GP; An DS; Chen IS; Kamata M
    PLoS One; 2012; 7(12):e53492. PubMed ID: 23300932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice.
    Myburgh R; Ivic S; Pepper MS; Gers-Huber G; Li D; Audigé A; Rochat MA; Jaquet V; Regenass S; Manz MG; Salmon P; Krause KH; Speck RF
    J Virol; 2015 Jul; 89(13):6761-72. PubMed ID: 25903342
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Positive results with autologous transplant of ZFN-modified CD4 T-cells: a step toward a practical, functional cure for HIV.
    AIDS Patient Care STDS; 2011 Nov; 25(11):693. PubMed ID: 22023317
    [No Abstract]   [Full Text] [Related]  

  • 7. CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo.
    Xu L; Yang H; Gao Y; Chen Z; Xie L; Liu Y; Liu Y; Wang X; Li H; Lai W; He Y; Yao A; Ma L; Shao Y; Zhang B; Wang C; Chen H; Deng H
    Mol Ther; 2017 Aug; 25(8):1782-1789. PubMed ID: 28527722
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5.
    Maier DA; Brennan AL; Jiang S; Binder-Scholl GK; Lee G; Plesa G; Zheng Z; Cotte J; Carpenito C; Wood T; Spratt SK; Ando D; Gregory P; Holmes MC; Perez EE; Riley JL; Carroll RG; June CH; Levine BL
    Hum Gene Ther; 2013 Mar; 24(3):245-58. PubMed ID: 23360514
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases.
    Wilen CB; Wang J; Tilton JC; Miller JC; Kim KA; Rebar EJ; Sherrill-Mix SA; Patro SC; Secreto AJ; Jordan AP; Lee G; Kahn J; Aye PP; Bunnell BA; Lackner AA; Hoxie JA; Danet-Desnoyers GA; Bushman FD; Riley JL; Gregory PD; June CH; Holmes MC; Doms RW
    PLoS Pathog; 2011 Apr; 7(4):e1002020. PubMed ID: 21533216
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases.
    Perez EE; Wang J; Miller JC; Jouvenot Y; Kim KA; Liu O; Wang N; Lee G; Bartsevich VV; Lee YL; Guschin DY; Rupniewski I; Waite AJ; Carpenito C; Carroll RG; Orange JS; Urnov FD; Rebar EJ; Ando D; Gregory PD; Riley JL; Holmes MC; June CH
    Nat Biotechnol; 2008 Jul; 26(7):808-16. PubMed ID: 18587387
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates.
    Peterson CW; Wang J; Norman KK; Norgaard ZK; Humbert O; Tse CK; Yan JJ; Trimble RG; Shivak DA; Rebar EJ; Gregory PD; Holmes MC; Kiem HP
    Blood; 2016 May; 127(20):2416-26. PubMed ID: 26980728
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo.
    Bai J; Gorantla S; Banda N; Cagnon L; Rossi J; Akkina R
    Mol Ther; 2000 Mar; 1(3):244-54. PubMed ID: 10933940
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Can HIV be cured with stem cell therapy?
    Deeks SG; McCune JM
    Nat Biotechnol; 2010 Aug; 28(8):807-10. PubMed ID: 20697404
    [No Abstract]   [Full Text] [Related]  

  • 14. CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4
    Xiao Q; Chen S; Wang Q; Liu Z; Liu S; Deng H; Hou W; Wu D; Xiong Y; Li J; Guo D
    Retrovirology; 2019 Jun; 16(1):15. PubMed ID: 31186067
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model.
    Shimizu S; Hong P; Arumugam B; Pokomo L; Boyer J; Koizumi N; Kittipongdaja P; Chen A; Bristol G; Galic Z; Zack JA; Yang O; Chen IS; Lee B; An DS
    Blood; 2010 Feb; 115(8):1534-44. PubMed ID: 20018916
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly.
    Kim HJ; Lee HJ; Kim H; Cho SW; Kim JS
    Genome Res; 2009 Jul; 19(7):1279-88. PubMed ID: 19470664
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A simultaneous knockout knockin genome editing strategy in HSPCs potently inhibits CCR5- and CXCR4-tropic HIV-1 infection.
    Dudek AM; Feist WN; Sasu EJ; Luna SE; Ben-Efraim K; Bak RO; Cepika AM; Porteus MH
    Cell Stem Cell; 2024 Apr; 31(4):499-518.e6. PubMed ID: 38579682
    [TBL] [Abstract][Full Text] [Related]  

  • 18. T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery.
    Swan CH; Bühler B; Steinberger P; Tschan MP; Barbas CF; Torbett BE
    Gene Ther; 2006 Oct; 13(20):1480-92. PubMed ID: 16738691
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Zinc-finger nucleases for somatic gene therapy: the next frontier.
    Rahman SH; Maeder ML; Joung JK; Cathomen T
    Hum Gene Ther; 2011 Aug; 22(8):925-33. PubMed ID: 21631241
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo.
    Sebastian NT; Zaikos TD; Terry V; Taschuk F; McNamara LA; Onafuwa-Nuga A; Yucha R; Signer RAJ; Riddell J; Bixby D; Markowitz N; Morrison SJ; Collins KL
    PLoS Pathog; 2017 Jul; 13(7):e1006509. PubMed ID: 28732051
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.