BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

442 related articles for article (PubMed ID: 20605919)

  • 1. Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence.
    Benson EK; Lee SW; Aaronson SA
    J Cell Sci; 2010 Aug; 123(Pt 15):2605-12. PubMed ID: 20605919
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome.
    Wheaton K; Campuzano D; Ma W; Sheinis M; Ho B; Brown GW; Benchimol S
    Mol Cell Biol; 2017 Jul; 37(14):. PubMed ID: 28483909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts.
    Cao K; Blair CD; Faddah DA; Kieckhaefer JE; Olive M; Erdos MR; Nabel EG; Collins FS
    J Clin Invest; 2011 Jul; 121(7):2833-44. PubMed ID: 21670498
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53.
    Kudlow BA; Stanfel MN; Burtner CR; Johnston ED; Kennedy BK
    Mol Biol Cell; 2008 Dec; 19(12):5238-48. PubMed ID: 18843043
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transient introduction of human telomerase mRNA improves hallmarks of progeria cells.
    Li Y; Zhou G; Bruno IG; Zhang N; Sho S; Tedone E; Lai TP; Cooke JP; Shay JW
    Aging Cell; 2019 Aug; 18(4):e12979. PubMed ID: 31152494
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.
    Liu GH; Barkho BZ; Ruiz S; Diep D; Qu J; Yang SL; Panopoulos AD; Suzuki K; Kurian L; Walsh C; Thompson J; Boue S; Fung HL; Sancho-Martinez I; Zhang K; Yates J; Izpisua Belmonte JC
    Nature; 2011 Apr; 472(7342):221-5. PubMed ID: 21346760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p53 isoforms regulate premature aging in human cells.
    von Muhlinen N; Horikawa I; Alam F; Isogaya K; Lissa D; Vojtesek B; Lane DP; Harris CC
    Oncogene; 2018 May; 37(18):2379-2393. PubMed ID: 29429991
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterochromatin loss as a determinant of progerin-induced DNA damage in Hutchinson-Gilford Progeria.
    Chojnowski A; Ong PF; Foo MXR; Liebl D; Hor LP; Stewart CL; Dreesen O
    Aging Cell; 2020 Mar; 19(3):e13108. PubMed ID: 32087607
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
    Chojnowski A; Ong PF; Wong ES; Lim JS; Mutalif RA; Navasankari R; Dutta B; Yang H; Liow YY; Sze SK; Boudier T; Wright GD; Colman A; Burke B; Stewart CL; Dreesen O
    Elife; 2015 Aug; 4():. PubMed ID: 26312502
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hutchinson-Gilford progeria syndrome through the lens of transcription.
    Prokocimer M; Barkan R; Gruenbaum Y
    Aging Cell; 2013 Aug; 12(4):533-43. PubMed ID: 23496208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes.
    Kreienkamp R; Croke M; Neumann MA; Bedia-Diaz G; Graziano S; Dusso A; Dorsett D; Carlberg C; Gonzalo S
    Oncotarget; 2016 May; 7(21):30018-31. PubMed ID: 27145372
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Towards delineating the chain of events that cause premature senescence in the accelerated aging syndrome Hutchinson-Gilford progeria (HGPS).
    Dreesen O
    Biochem Soc Trans; 2020 Jun; 48(3):981-991. PubMed ID: 32539085
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Telomerase therapy reverses vascular senescence and extends lifespan in progeria mice.
    Mojiri A; Walther BK; Jiang C; Matrone G; Holgate R; Xu Q; Morales E; Wang G; Gu J; Wang R; Cooke JP
    Eur Heart J; 2021 Nov; 42(42):4352-4369. PubMed ID: 34389865
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome.
    Aguado J; Sola-Carvajal A; Cancila V; Revêchon G; Ong PF; Jones-Weinert CW; Wallén Arzt E; Lattanzi G; Dreesen O; Tripodo C; Rossiello F; Eriksson M; d'Adda di Fagagna F
    Nat Commun; 2019 Nov; 10(1):4990. PubMed ID: 31740672
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epigenetic involvement in Hutchinson-Gilford progeria syndrome: a mini-review.
    Arancio W; Pizzolanti G; Genovese SI; Pitrone M; Giordano C
    Gerontology; 2014; 60(3):197-203. PubMed ID: 24603298
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations.
    Gonzalo S; Kreienkamp R; Askjaer P
    Ageing Res Rev; 2017 Jan; 33():18-29. PubMed ID: 27374873
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
    Finley J
    Med Hypotheses; 2018 Sep; 118():151-162. PubMed ID: 30037605
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A.
    Musich PR; Zou Y
    Aging (Albany NY); 2009 Jan; 1(1):28-37. PubMed ID: 19851476
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Molecular and Cellular Basis of Hutchinson-Gilford Progeria Syndrome and Potential Treatments.
    Batista NJ; Desai SG; Perez AM; Finkelstein A; Radigan R; Singh M; Landman A; Drittel B; Abramov D; Ahsan M; Cornwell S; Zhang D
    Genes (Basel); 2023 Feb; 14(3):. PubMed ID: 36980874
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Association of progerin-interactive partner proteins with lamina proteins: Mel18 is associated with emerin in HGPS.
    Ju WN; Brown WT; Zhong N
    Beijing Da Xue Xue Bao Yi Xue Ban; 2009 Aug; 41(4):397-401. PubMed ID: 19727227
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.