204 related articles for article (PubMed ID: 20606004)
1. In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats.
Yanni SB; Augustijns PF; Benjamin DK; Brouwer KL; Thakker DR; Annaert PP
Drug Metab Dispos; 2010 Oct; 38(10):1848-56. PubMed ID: 20606004
[TBL] [Abstract][Full Text] [Related]
2. Higher clearance of micafungin in neonates compared with adults: role of age-dependent micafungin serum binding.
Yanni SB; Smith PB; Benjamin DK; Augustijns PF; Thakker DR; Annaert PP
Biopharm Drug Dispos; 2011 May; 32(4):222-32. PubMed ID: 21449041
[TBL] [Abstract][Full Text] [Related]
3. Evaluation of the endothelin receptor antagonists ambrisentan, bosentan, macitentan, and sitaxsentan as hepatobiliary transporter inhibitors and substrates in sandwich-cultured human hepatocytes.
Lepist EI; Gillies H; Smith W; Hao J; Hubert C; St Claire RL; Brouwer KR; Ray AS
PLoS One; 2014; 9(1):e87548. PubMed ID: 24498134
[TBL] [Abstract][Full Text] [Related]
4. Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury.
Li X; Zhong K; Guo Z; Zhong D; Chen X
Drug Metab Dispos; 2015 Nov; 43(11):1751-9. PubMed ID: 26276582
[TBL] [Abstract][Full Text] [Related]
5. Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes.
Hartman JC; Brouwer K; Mandagere A; Melvin L; Gorczynski R
Can J Physiol Pharmacol; 2010 Jun; 88(6):682-91. PubMed ID: 20628435
[TBL] [Abstract][Full Text] [Related]
6. Estimation of transporters involved in the hepatobiliary transport of TA-0201CA using sandwich-cultured rat hepatocytes from normal and multidrug resistance-associated protein 2-deficient rats.
Fukuda H; Ohashi R; Ohashi N; Yabuuchi H; Tamai I
Drug Metab Dispos; 2010 Sep; 38(9):1505-13. PubMed ID: 20538722
[TBL] [Abstract][Full Text] [Related]
7. Optimized Hepatocyte-Like Cells with Functional Drug Transporters Directly-Reprogrammed from Mouse Fibroblasts and their Potential in Drug Disposition and Toxicology.
Wu ZT; Yao D; Ji SY; Ni X; Gao YM; Hui LJ; Pan GY
Cell Physiol Biochem; 2016; 38(5):1815-30. PubMed ID: 27160211
[TBL] [Abstract][Full Text] [Related]
8. Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1)by bosentan: a mechanism for species differences in hepatotoxicity.
Leslie EM; Watkins PB; Kim RB; Brouwer KL
J Pharmacol Exp Ther; 2007 Jun; 321(3):1170-8. PubMed ID: 17374746
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs.
Mita S; Suzuki H; Akita H; Hayashi H; Onuki R; Hofmann AF; Sugiyama Y
Drug Metab Dispos; 2006 Sep; 34(9):1575-81. PubMed ID: 16760228
[TBL] [Abstract][Full Text] [Related]
10. Endogenous bile acid disposition in rat and human sandwich-cultured hepatocytes.
Marion TL; Perry CH; St Claire RL; Brouwer KL
Toxicol Appl Pharmacol; 2012 May; 261(1):1-9. PubMed ID: 22342602
[TBL] [Abstract][Full Text] [Related]
11. Involvement of multidrug resistance-associated protein 2 (ABCC2/Mrp2) in biliary excretion of micafungin in rats.
Abe F; Ueyama J; Kimata A; Kato M; Hayashi T; Nadai M; Saito H; Takeyama N; Noguchi H; Hasegawa T
Life Sci; 2008 Aug; 83(7-8):229-35. PubMed ID: 18638490
[TBL] [Abstract][Full Text] [Related]
12. Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes.
Guo C; He L; Yao D; A J; Cao B; Ren J; Wang G; Pan G
Toxicol Lett; 2014 Jan; 224(1):93-100. PubMed ID: 24120425
[TBL] [Abstract][Full Text] [Related]
13. Endotoxin does not alter the pharmacokinetics of micafungin, but it impairs biliary excretion of micafungin via multidrug resistance-associated protein 2 (ABCC2/Mrp2) in rats.
Noda T; Abe F; Ueyama J; Kato M; Katoh M; Nadai M; Saito H; Hasegawa T
J Infect Chemother; 2011 Apr; 17(2):207-13. PubMed ID: 20835743
[TBL] [Abstract][Full Text] [Related]
14. Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes.
Rippin SJ; Hagenbuch B; Meier PJ; Stieger B
Hepatology; 2001 Apr; 33(4):776-82. PubMed ID: 11283839
[TBL] [Abstract][Full Text] [Related]
15. The role of the sodium-taurocholate cotransporting polypeptide (NTCP) and of the bile salt export pump (BSEP) in physiology and pathophysiology of bile formation.
Stieger B
Handb Exp Pharmacol; 2011; (201):205-59. PubMed ID: 21103971
[TBL] [Abstract][Full Text] [Related]
16. Confocal imaging with a fluorescent bile acid analogue closely mimicking hepatic taurocholate disposition.
De Bruyn T; Sempels W; Snoeys J; Holmstock N; Chatterjee S; Stieger B; Augustijns P; Hofkens J; Mizuno H; Annaert P
J Pharm Sci; 2014 Jun; 103(6):1872-81. PubMed ID: 24652646
[TBL] [Abstract][Full Text] [Related]
17. Hepatobiliary disposition of 3alpha,6alpha,7alpha,12alpha-tetrahydroxy-cholanoyl taurine: a substrate for multiple canalicular transporters.
Megaraj V; Iida T; Jungsuwadee P; Hofmann AF; Vore M
Drug Metab Dispos; 2010 Oct; 38(10):1723-30. PubMed ID: 20643783
[TBL] [Abstract][Full Text] [Related]
18. Use of cassette dosing in sandwich-cultured rat and human hepatocytes to identify drugs that inhibit bile acid transport.
Wolf KK; Vora S; Webster LO; Generaux GT; Polli JW; Brouwer KL
Toxicol In Vitro; 2010 Feb; 24(1):297-309. PubMed ID: 19706322
[TBL] [Abstract][Full Text] [Related]
19. The impact of solute carrier (SLC) drug uptake transporter loss in human and rat cryopreserved hepatocytes on clearance predictions.
Lundquist P; Lööf J; Sohlenius-Sternbeck AK; Floby E; Johansson J; Bylund J; Hoogstraate J; Afzelius L; Andersson TB
Drug Metab Dispos; 2014 Mar; 42(3):469-80. PubMed ID: 24396146
[TBL] [Abstract][Full Text] [Related]
20. Xenobiotics inhibit hepatic uptake and biliary excretion of taurocholate in rat hepatocytes.
Kemp DC; Zamek-Gliszczynski MJ; Brouwer KL
Toxicol Sci; 2005 Feb; 83(2):207-14. PubMed ID: 15509663
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]