BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

971 related articles for article (PubMed ID: 20606625)

  • 1. ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.
    Dormann D; Rodde R; Edbauer D; Bentmann E; Fischer I; Hruscha A; Than ME; Mackenzie IR; Capell A; Schmid B; Neumann M; Haass C
    EMBO J; 2010 Aug; 29(16):2841-57. PubMed ID: 20606625
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.
    Dormann D; Madl T; Valori CF; Bentmann E; Tahirovic S; Abou-Ajram C; Kremmer E; Ansorge O; Mackenzie IR; Neumann M; Haass C
    EMBO J; 2012 Nov; 31(22):4258-75. PubMed ID: 22968170
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis-FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS inclusions.
    Troakes C; Hortobágyi T; Vance C; Al-Sarraj S; Rogelj B; Shaw CE
    Neuropathol Appl Neurobiol; 2013 Aug; 39(5):553-61. PubMed ID: 22934812
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear import factor transportin and arginine methyltransferase 1 modify FUS neurotoxicity in Drosophila.
    Jäckel S; Summerer AK; Thömmes CM; Pan X; Voigt A; Schulz JB; Rasse TM; Dormann D; Haass C; Kahle PJ
    Neurobiol Dis; 2015 Feb; 74():76-88. PubMed ID: 25447237
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.
    Neumann M; Bentmann E; Dormann D; Jawaid A; DeJesus-Hernandez M; Ansorge O; Roeber S; Kretzschmar HA; Munoz DG; Kusaka H; Yokota O; Ang LC; Bilbao J; Rademakers R; Haass C; Mackenzie IR
    Brain; 2011 Sep; 134(Pt 9):2595-609. PubMed ID: 21856723
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
    Neumann M; Valori CF; Ansorge O; Kretzschmar HA; Munoz DG; Kusaka H; Yokota O; Ishihara K; Ang LC; Bilbao JM; Mackenzie IR
    Acta Neuropathol; 2012 Nov; 124(5):705-16. PubMed ID: 22842875
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impaired nuclear transport induced by juvenile ALS causing P525L mutation in NLS domain of FUS: A molecular mechanistic study.
    Basu S; Rajendra KC; Alagar S; Bahadur RP
    Biochim Biophys Acta Proteins Proteom; 2022 Apr; 1870(4):140766. PubMed ID: 35134572
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS).
    Zhang ZC; Chook YM
    Proc Natl Acad Sci U S A; 2012 Jul; 109(30):12017-21. PubMed ID: 22778397
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear localization sequence of FUS and induction of stress granules by ALS mutants.
    Gal J; Zhang J; Kwinter DM; Zhai J; Jia H; Jia J; Zhu H
    Neurobiol Aging; 2011 Dec; 32(12):2323.e27-40. PubMed ID: 20674093
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
    Hofweber M; Hutten S; Bourgeois B; Spreitzer E; Niedner-Boblenz A; Schifferer M; Ruepp MD; Simons M; Niessing D; Madl T; Dormann D
    Cell; 2018 Apr; 173(3):706-719.e13. PubMed ID: 29677514
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import.
    Darovic S; Prpar Mihevc S; Župunski V; Gunčar G; Štalekar M; Lee YB; Shaw CE; Rogelj B
    J Cell Sci; 2015 Nov; 128(22):4151-9. PubMed ID: 26403203
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FUS-NLS/Transportin 1 complex structure provides insights into the nuclear targeting mechanism of FUS and the implications in ALS.
    Niu C; Zhang J; Gao F; Yang L; Jia M; Zhu H; Gong W
    PLoS One; 2012; 7(10):e47056. PubMed ID: 23056579
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.
    Vance C; Scotter EL; Nishimura AL; Troakes C; Mitchell JC; Kathe C; Urwin H; Manser C; Miller CC; Hortobágyi T; Dragunow M; Rogelj B; Shaw CE
    Hum Mol Genet; 2013 Jul; 22(13):2676-88. PubMed ID: 23474818
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophagy regulates amyotrophic lateral sclerosis-linked fused in sarcoma-positive stress granules in neurons.
    Ryu HH; Jun MH; Min KJ; Jang DJ; Lee YS; Kim HK; Lee JA
    Neurobiol Aging; 2014 Dec; 35(12):2822-2831. PubMed ID: 25216585
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.
    Verbeeck C; Deng Q; Dejesus-Hernandez M; Taylor G; Ceballos-Diaz C; Kocerha J; Golde T; Das P; Rademakers R; Dickson DW; Kukar T
    Mol Neurodegener; 2012 Oct; 7():53. PubMed ID: 23046583
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
    Gonzalez A; Mannen T; Çağatay T; Fujiwara A; Matsumura H; Niesman AB; Brautigam CA; Chook YM; Yoshizawa T
    Sci Rep; 2021 Feb; 11(1):3754. PubMed ID: 33580145
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fused in sarcoma (FUS): an oncogene goes awry in neurodegeneration.
    Dormann D; Haass C
    Mol Cell Neurosci; 2013 Sep; 56():475-86. PubMed ID: 23557964
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS.
    Ito D; Suzuki N
    Neurology; 2011 Oct; 77(17):1636-43. PubMed ID: 21956718
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43).
    Bentmann E; Neumann M; Tahirovic S; Rodde R; Dormann D; Haass C
    J Biol Chem; 2012 Jun; 287(27):23079-94. PubMed ID: 22563080
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
    Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
    Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 49.