These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 20610151)

  • 1. Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials.
    Deng X; Nagle A; Wu T; Sakata T; Henson K; Chen Z; Kuhen K; Plouffe D; Winzeler E; Adrian F; Tuntland T; Chang J; Simerson S; Howard S; Ek J; Isbell J; Tully DC; Chatterjee AK; Gray NS
    Bioorg Med Chem Lett; 2010 Jul; 20(14):4027-31. PubMed ID: 20610151
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and in vitro evaluation of novel 8-aminoquinoline-pyrazolopyrimidine hybrids as potent antimalarial agents.
    Kannan M; Raichurkar AV; Khan FR; Iyer PS
    Bioorg Med Chem Lett; 2015 Mar; 25(5):1100-3. PubMed ID: 25650255
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of 2,4,6-trisubstituted pyrimidines as antimalarial agents.
    Agarwal A; Srivastava K; Puri SK; Chauhan PM
    Bioorg Med Chem; 2005 Aug; 13(15):4645-50. PubMed ID: 15896965
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of carbohybrid-based 2-aminopyrimidine analogues as a new class of rapid-acting antimalarial agents using image-based cytological profiling assay.
    Lee S; Lim D; Lee E; Lee N; Lee HG; Cechetto J; Liuzzi M; Freitas-Junior LH; Song JS; Bae MA; Oh S; Ayong L; Park SB
    J Med Chem; 2014 Sep; 57(17):7425-34. PubMed ID: 25137549
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials.
    Norcross NR; Baragaña B; Wilson C; Hallyburton I; Osuna-Cabello M; Norval S; Riley J; Stojanovski L; Simeons FR; Porzelle A; Grimaldi R; Wittlin S; Duffy S; Avery VM; Meister S; Sanz L; Jiménez-Díaz B; Angulo-Barturen I; Ferrer S; Martínez MS; Gamo FJ; Frearson JA; Gray DW; Fairlamb AH; Winzeler EA; Waterson D; Campbell SF; Willis P; Read KD; Gilbert IH
    J Med Chem; 2016 Jul; 59(13):6101-20. PubMed ID: 27314305
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines.
    Martyn DC; Nijjar A; Celatka CA; Mazitschek R; Cortese JF; Tyndall E; Liu H; Fitzgerald MM; O'Shea TJ; Danthi S; Clardy J
    Bioorg Med Chem Lett; 2010 Jan; 20(1):228-31. PubMed ID: 19914064
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and structure-activity relationships of 4-pyridones as potential antimalarials.
    Yeates CL; Batchelor JF; Capon EC; Cheesman NJ; Fry M; Hudson AT; Pudney M; Trimming H; Woolven J; Bueno JM; Chicharro J; Fernández E; Fiandor JM; Gargallo-Viola D; Gómez de las Heras F; Herreros E; León ML
    J Med Chem; 2008 May; 51(9):2845-52. PubMed ID: 18396855
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological activity of 5-aryl-4-(4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl)pyrimidine analogs as potent, highly selective, and orally bioavailable NHE-1 inhibitors.
    Atwal KS; O'Neil SV; Ahmad S; Doweyko L; Kirby M; Dorso CR; Chandrasena G; Chen BC; Zhao R; Zahler R
    Bioorg Med Chem Lett; 2006 Sep; 16(18):4796-9. PubMed ID: 16870436
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tetraoxane-pyrimidine nitrile hybrids as dual stage antimalarials.
    Oliveira R; Guedes RC; Meireles P; Albuquerque IS; Gonçalves LM; Pires E; Bronze MR; Gut J; Rosenthal PJ; Prudêncio M; Moreira R; O'Neill PM; Lopes F
    J Med Chem; 2014 Jun; 57(11):4916-23. PubMed ID: 24824551
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, characterization and antimalarial activity of quinoline-pyrimidine hybrids.
    Pretorius SI; Breytenbach WJ; de Kock C; Smith PJ; N'Da DD
    Bioorg Med Chem; 2013 Jan; 21(1):269-77. PubMed ID: 23168082
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ferrocene-pyrimidine conjugates: Synthesis, electrochemistry, physicochemical properties and antiplasmodial activities.
    Chopra R; de Kock C; Smith P; Chibale K; Singh K
    Eur J Med Chem; 2015 Jul; 100():1-9. PubMed ID: 26057222
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A small library of trisubstituted pyrimidines as antimalarial and antitubercular agents.
    Agarwal A; Srivastava K; Puri SK; Sinha S; Chauhan PM
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5218-21. PubMed ID: 16171994
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expeditious synthesis and biological evaluation of novel 2,N6-disubstituted 1,2-dihydro-1,3,5-triazine-4,6-diamines as potential antimalarials.
    Gravestock D; Rousseau AL; Lourens AC; Moleele SS; van Zyl RL; Steenkamp PA
    Eur J Med Chem; 2011 Jun; 46(6):2022-30. PubMed ID: 21420762
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity.
    Chen X; Chong CR; Shi L; Yoshimoto T; Sullivan DJ; Liu JO
    Proc Natl Acad Sci U S A; 2006 Sep; 103(39):14548-53. PubMed ID: 16983082
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Target guided synthesis of 5-benzyl-2,4-diamonopyrimidines: their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from Plasmodium falciparum.
    Sirichaiwat C; Intaraudom C; Kamchonwongpaisan S; Vanichtanankul J; Thebtaranonth Y; Yuthavong Y
    J Med Chem; 2004 Jan; 47(2):345-54. PubMed ID: 14711307
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and structure-activity relationships of (1H-pyridin-4-ylidene)amines as potential antimalarials.
    Rodrigues T; Guedes RC; dos Santos DJ; Carrasco M; Gut J; Rosenthal PJ; Moreira R; Lopes F
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3476-80. PubMed ID: 19467600
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidines.
    Gonzàlez Cabrera D; Douelle F; Le Manach C; Han Z; Paquet T; Taylor D; Njoroge M; Lawrence N; Wiesner L; Waterson D; Witty MJ; Wittlin S; Street LJ; Chibale K
    J Med Chem; 2015 Sep; 58(18):7572-9. PubMed ID: 26322748
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antimalarial and antiplasmodial activities of norneolignans. Syntheses and SAR.
    Skytte DM; Nielsen SF; Chen M; Zhai L; Olsen CE; Christensen SB
    J Med Chem; 2006 Jan; 49(1):436-40. PubMed ID: 16392829
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potent 4-aminopiperidine based antimalarial agents.
    Brinner KM; Powles MA; Schmatz DM; Ellman JA
    Bioorg Med Chem Lett; 2005 Jan; 15(2):345-8. PubMed ID: 15603951
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts.
    Musonda CC; Taylor D; Lehman J; Gut J; Rosenthal PJ; Chibale K
    Bioorg Med Chem Lett; 2004 Aug; 14(15):3901-5. PubMed ID: 15225694
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.