BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 20610632)

  • 1. Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer.
    Singha PK; Yeh IT; Venkatachalam MA; Saikumar P
    Cancer Res; 2010 Aug; 70(15):6377-83. PubMed ID: 20610632
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C18 ORF1, a novel negative regulator of transforming growth factor-β signaling.
    Nakano N; Maeyama K; Sakata N; Itoh F; Akatsu R; Nakata M; Katsu Y; Ikeno S; Togawa Y; Vo Nguyen TT; Watanabe Y; Kato M; Itoh S
    J Biol Chem; 2014 May; 289(18):12680-92. PubMed ID: 24627487
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TMEPAI inhibits TGF-β signaling by promoting lysosome degradation of TGF-β receptor and contributes to lung cancer development.
    Bai X; Jing L; Li Y; Li Y; Luo S; Wang S; Zhou J; Liu Z; Diao A
    Cell Signal; 2014 Sep; 26(9):2030-9. PubMed ID: 24933703
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PMEPA1/TMEPAI isoforms function via its PY and Smad-interaction motifs for tumorigenic activities of breast cancer cells.
    Puteri MU; Watanabe Y; Wardhani BWK; Amalia R; Abdelaziz M; Kato M
    Genes Cells; 2020 Jun; 25(6):375-390. PubMed ID: 32181976
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling.
    Watanabe Y; Itoh S; Goto T; Ohnishi E; Inamitsu M; Itoh F; Satoh K; Wiercinska E; Yang W; Shi L; Tanaka A; Nakano N; Mommaas AM; Shibuya H; Ten Dijke P; Kato M
    Mol Cell; 2010 Jan; 37(1):123-34. PubMed ID: 20129061
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells.
    Deckers M; van Dinther M; Buijs J; Que I; Löwik C; van der Pluijm G; ten Dijke P
    Cancer Res; 2006 Feb; 66(4):2202-9. PubMed ID: 16489022
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells.
    Vo Nguyen TT; Watanabe Y; Shiba A; Noguchi M; Itoh S; Kato M
    Cancer Sci; 2014 Mar; 105(3):334-41. PubMed ID: 24438557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TGF-β induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer.
    Singha PK; Pandeswara S; Geng H; Lan R; Venkatachalam MA; Saikumar P
    Genes Cancer; 2014 Sep; 5(9-10):320-36. PubMed ID: 25352949
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene.
    Nakano N; Itoh S; Watanabe Y; Maeyama K; Itoh F; Kato M
    J Biol Chem; 2010 Dec; 285(49):38023-33. PubMed ID: 20889500
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppression of motor protein KIF3C expression inhibits tumor growth and metastasis in breast cancer by inhibiting TGF-β signaling.
    Wang C; Wang C; Wei Z; Li Y; Wang W; Li X; Zhao J; Zhou X; Qu X; Xiang F
    Cancer Lett; 2015 Nov; 368(1):105-114. PubMed ID: 26272184
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer.
    Singha PK; Pandeswara S; Geng H; Lan R; Venkatachalam MA; Dobi A; Srivastava S; Saikumar P
    Genes Cancer; 2019; 10(5-6):134-149. PubMed ID: 31798766
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Consequences of altered TGF-beta expression and responsiveness in breast cancer: evidence for autocrine and paracrine effects.
    Tobin SW; Douville K; Benbow U; Brinckerhoff CE; Memoli VA; Arrick BA
    Oncogene; 2002 Jan; 21(1):108-18. PubMed ID: 11791181
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of RAB1B promotes triple-negative breast cancer metastasis by activating TGF-β/SMAD signaling.
    Jiang HL; Sun HF; Gao SP; Li LD; Hu X; Wu J; Jin W
    Oncotarget; 2015 Jun; 6(18):16352-65. PubMed ID: 25970785
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinct roles of transforming growth factor-β signaling and transforming growth factor-β receptor inhibitor SB431542 in the regulation of p21 expression.
    Koo BH; Kim Y; Je Cho Y; Kim DS
    Eur J Pharmacol; 2015 Oct; 764():413-423. PubMed ID: 26187313
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transcriptional deregulation of VEGF, FGF2, TGF-beta1, 2, 3 and cognate receptors in breast tumorigenesis.
    Soufla G; Porichis F; Sourvinos G; Vassilaros S; Spandidos DA
    Cancer Lett; 2006 Apr; 235(1):100-13. PubMed ID: 15949894
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Long non-coding RNAs (LncRNA) regulated by transforming growth factor (TGF) β: LncRNA-hit-mediated TGFβ-induced epithelial to mesenchymal transition in mammary epithelia.
    Richards EJ; Zhang G; Li ZP; Permuth-Wey J; Challa S; Li Y; Kong W; Dan S; Bui MM; Coppola D; Mao WM; Sellers TA; Cheng JQ
    J Biol Chem; 2015 Mar; 290(11):6857-67. PubMed ID: 25605728
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression and secretion of TGF-beta isoforms and expression of TGF-beta-receptors I, II and III in normal and neoplastic human breast.
    Chakravarthy D; Green AR; Green VL; Kerin MJ; Speirs V
    Int J Oncol; 1999 Jul; 15(1):187-94. PubMed ID: 10375614
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TMEPAI/PMEPA1 inhibits Wnt signaling by regulating β-catenin stability and nuclear accumulation in triple negative breast cancer cells.
    Amalia R; Abdelaziz M; Puteri MU; Hwang J; Anwar F; Watanabe Y; Kato M
    Cell Signal; 2019 Jul; 59():24-33. PubMed ID: 30890370
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth.
    Micalizzi DS; Wang CA; Farabaugh SM; Schiemann WP; Ford HL
    Cancer Res; 2010 Dec; 70(24):10371-80. PubMed ID: 21056993
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TMEPAI family: involvement in regulation of multiple signalling pathways.
    Itoh S; Itoh F
    J Biochem; 2018 Sep; 164(3):195-204. PubMed ID: 29945215
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.