BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 20628002)

  • 1. Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation.
    Chen W; Luo Y; Liu L; Zhou H; Xu B; Han X; Shen T; Liu Z; Lu Y; Huang S
    Cancer Prev Res (Phila); 2010 Aug; 3(8):1015-25. PubMed ID: 20628002
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells.
    Chen W; Pan Y; Wang S; Liu Y; Chen G; Zhou L; Ni W; Wang A; Lu Y
    BMC Cancer; 2017 Jan; 17(1):34. PubMed ID: 28061838
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cryptotanshinone inhibition of mammalian target of rapamycin pathway is dependent on oestrogen receptor alpha in breast cancer.
    Pan Y; Shi J; Ni W; Liu Y; Wang S; Wang X; Wei Z; Wang A; Chen W; Lu Y
    J Cell Mol Med; 2017 Sep; 21(9):2129-2139. PubMed ID: 28272775
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The molecular target of rapamycin (mTOR) as a therapeutic target against cancer.
    Mita MM; Mita A; Rowinsky EK
    Cancer Biol Ther; 2003; 2(4 Suppl 1):S169-77. PubMed ID: 14508096
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells.
    Le XF; Arachchige-Don AS; Mao W; Horne MC; Bast RC
    Mol Cancer Ther; 2007 Nov; 6(11):2843-57. PubMed ID: 18025271
    [TBL] [Abstract][Full Text] [Related]  

  • 6. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
    Gao N; Flynn DC; Zhang Z; Zhong XS; Walker V; Liu KJ; Shi X; Jiang BH
    Am J Physiol Cell Physiol; 2004 Aug; 287(2):C281-91. PubMed ID: 15028555
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cryptotanshinone induces cell cycle arrest and apoptosis of multidrug resistant human chronic myeloid leukemia cells by inhibiting the activity of eukaryotic initiation factor 4E.
    Ge Y; Cheng R; Zhou Y; Shen J; Peng L; Xu X; Dai Q; Liu P; Wang H; Ma X; Jia J; Chen Z
    Mol Cell Biochem; 2012 Sep; 368(1-2):17-25. PubMed ID: 22614784
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer: a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation.
    Chang WL; Hsu LC; Leu WJ; Chen CS; Guh JH
    Oncotarget; 2015 Nov; 6(37):39806-20. PubMed ID: 26447757
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Determinants of rapamycin sensitivity in breast cancer cells.
    Noh WC; Mondesire WH; Peng J; Jian W; Zhang H; Dong J; Mills GB; Hung MC; Meric-Bernstam F
    Clin Cancer Res; 2004 Feb; 10(3):1013-23. PubMed ID: 14871980
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cryptotanshinone acts synergistically with imatinib to induce apoptosis of human chronic myeloid leukemia cells.
    Ge Y; Yang B; Xu X; Dai Q; Chen Z; Cheng R
    Leuk Lymphoma; 2015 Mar; 56(3):730-8. PubMed ID: 24884318
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation.
    Paternot S; Roger PP
    Cancer Res; 2009 Jun; 69(11):4577-81. PubMed ID: 19458076
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Carbon monoxide releasing molecule-2 CORM-2 represses global protein synthesis by inhibition of eukaryotic elongation factor eEF2.
    Schwer CI; Stoll P; Rospert S; Fitzke E; Schallner N; Bürkle H; Schmidt R; Humar M
    Int J Biochem Cell Biol; 2013 Feb; 45(2):201-12. PubMed ID: 23041477
    [TBL] [Abstract][Full Text] [Related]  

  • 13. mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators.
    Nader GA; McLoughlin TJ; Esser KA
    Am J Physiol Cell Physiol; 2005 Dec; 289(6):C1457-65. PubMed ID: 16079186
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interleukin-8 signaling promotes translational regulation of cyclin D in androgen-independent prostate cancer cells.
    MacManus CF; Pettigrew J; Seaton A; Wilson C; Maxwell PJ; Berlingeri S; Purcell C; McGurk M; Johnston PG; Waugh DJ
    Mol Cancer Res; 2007 Jul; 5(7):737-48. PubMed ID: 17606477
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin: a new molecular target for breast cancer.
    Mita MM; Mita A; Rowinsky EK
    Clin Breast Cancer; 2003 Jun; 4(2):126-37. PubMed ID: 12864941
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.
    Srethapakdi M; Liu F; Tavorath R; Rosen N
    Cancer Res; 2000 Jul; 60(14):3940-6. PubMed ID: 10919672
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of PI3K/AKT molecular pathway mediated by membrane estrogen receptor GPER accounts for cryptotanshinone induced antiproliferative effect on breast cancer SKBR-3 cells.
    Shi D; Zhao P; Cui L; Li H; Sun L; Niu J; Chen M
    BMC Pharmacol Toxicol; 2020 May; 21(1):32. PubMed ID: 32357920
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro.
    Gorshtein A; Rubinfeld H; Kendler E; Theodoropoulou M; Cerovac V; Stalla GK; Cohen ZR; Hadani M; Shimon I
    Endocr Relat Cancer; 2009 Sep; 16(3):1017-27. PubMed ID: 19509067
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RAF inhibitor LY3009120 sensitizes RAS or BRAF mutant cancer to CDK4/6 inhibition by abemaciclib via superior inhibition of phospho-RB and suppression of cyclin D1.
    Chen SH; Gong X; Zhang Y; Van Horn RD; Yin T; Huber L; Burke TF; Manro J; Iversen PW; Wu W; Bhagwat SV; Beckmann RP; Tiu RV; Buchanan SG; Peng SB
    Oncogene; 2018 Feb; 37(6):821-832. PubMed ID: 29059158
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation.
    Mukhopadhyay A; Banerjee S; Stafford LJ; Xia C; Liu M; Aggarwal BB
    Oncogene; 2002 Dec; 21(57):8852-61. PubMed ID: 12483537
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.