These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
451 related articles for article (PubMed ID: 20630094)
1. Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032. Rubinstein JC; Sznol M; Pavlick AC; Ariyan S; Cheng E; Bacchiocchi A; Kluger HM; Narayan D; Halaban R J Transl Med; 2010 Jul; 8():67. PubMed ID: 20630094 [TBL] [Abstract][Full Text] [Related]
2. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nazarian R; Shi H; Wang Q; Kong X; Koya RC; Lee H; Chen Z; Lee MK; Attar N; Sazegar H; Chodon T; Nelson SF; McArthur G; Sosman JA; Ribas A; Lo RS Nature; 2010 Dec; 468(7326):973-7. PubMed ID: 21107323 [TBL] [Abstract][Full Text] [Related]
3. Analytical performance of a real-time PCR-based assay for V600 mutations in the BRAF gene, used as the companion diagnostic test for the novel BRAF inhibitor vemurafenib in metastatic melanoma. Halait H; Demartin K; Shah S; Soviero S; Langland R; Cheng S; Hillman G; Wu L; Lawrence HJ Diagn Mol Pathol; 2012 Mar; 21(1):1-8. PubMed ID: 22306669 [TBL] [Abstract][Full Text] [Related]
4. Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAF mutations. Ihle MA; Fassunke J; König K; Grünewald I; Schlaak M; Kreuzberg N; Tietze L; Schildhaus HU; Büttner R; Merkelbach-Bruse S BMC Cancer; 2014 Jan; 14():13. PubMed ID: 24410877 [TBL] [Abstract][Full Text] [Related]
5. Allele frequencies of BRAFV600 mutations in primary melanomas and matched metastases and their relevance for BRAF inhibitor therapy in metastatic melanoma. Satzger I; Marks L; Kerick M; Klages S; Berking C; Herbst R; Völker B; Schacht V; Timmermann B; Gutzmer R Oncotarget; 2015 Nov; 6(35):37895-905. PubMed ID: 26498143 [TBL] [Abstract][Full Text] [Related]
6. Vemurafenib in patients with BRAF V600E mutation-positive advanced melanoma. Ravnan MC; Matalka MS Clin Ther; 2012 Jul; 34(7):1474-86. PubMed ID: 22742884 [TBL] [Abstract][Full Text] [Related]
11. Vemurafenib in patients with BRAF(V600) mutated metastatic melanoma: an open-label, multicentre, safety study. Larkin J; Del Vecchio M; Ascierto PA; Krajsova I; Schachter J; Neyns B; Espinosa E; Garbe C; Sileni VC; Gogas H; Miller WH; Mandalà M; Hospers GA; Arance A; Queirolo P; Hauschild A; Brown MP; Mitchell L; Veronese L; Blank CU Lancet Oncol; 2014 Apr; 15(4):436-44. PubMed ID: 24582505 [TBL] [Abstract][Full Text] [Related]
12. Treatment of BRAF-mutant melanoma: the role of vemurafenib and other therapies. Jang S; Atkins MB Clin Pharmacol Ther; 2014 Jan; 95(1):24-31. PubMed ID: 24080641 [TBL] [Abstract][Full Text] [Related]
13. Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM. Rohrbeck L; Gong JN; Lee EF; Kueh AJ; Behren A; Tai L; Lessene G; Huang DC; Fairlie WD; Strasser A; Herold MJ Cell Death Differ; 2016 Dec; 23(12):2054-2062. PubMed ID: 27689874 [TBL] [Abstract][Full Text] [Related]
14. The role of BRAF V600 mutation in melanoma. Ascierto PA; Kirkwood JM; Grob JJ; Simeone E; Grimaldi AM; Maio M; Palmieri G; Testori A; Marincola FM; Mozzillo N J Transl Med; 2012 Jul; 10():85. PubMed ID: 22554099 [TBL] [Abstract][Full Text] [Related]
15. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Bollag G; Hirth P; Tsai J; Zhang J; Ibrahim PN; Cho H; Spevak W; Zhang C; Zhang Y; Habets G; Burton EA; Wong B; Tsang G; West BL; Powell B; Shellooe R; Marimuthu A; Nguyen H; Zhang KY; Artis DR; Schlessinger J; Su F; Higgins B; Iyer R; D'Andrea K; Koehler A; Stumm M; Lin PS; Lee RJ; Grippo J; Puzanov I; Kim KB; Ribas A; McArthur GA; Sosman JA; Chapman PB; Flaherty KT; Xu X; Nathanson KL; Nolop K Nature; 2010 Sep; 467(7315):596-9. PubMed ID: 20823850 [TBL] [Abstract][Full Text] [Related]
16. PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas. Lee JT; Li L; Brafford PA; van den Eijnden M; Halloran MB; Sproesser K; Haass NK; Smalley KS; Tsai J; Bollag G; Herlyn M Pigment Cell Melanoma Res; 2010 Dec; 23(6):820-7. PubMed ID: 20973932 [TBL] [Abstract][Full Text] [Related]
17. A HRM assay for identification of low level BRAF V600E and V600K mutations using the CADMA principle in FFPE specimens. Huebner C; Weber R; Lloydd R Pathology; 2017 Dec; 49(7):776-783. PubMed ID: 29100713 [TBL] [Abstract][Full Text] [Related]
18. Is a single BRAF wild-type test sufficient to exclude melanoma patients from vemurafenib therapy? Saint-Jean M; Quéreux G; Nguyen JM; Peuvrel L; Brocard A; Vallée A; Knol AC; Khammari A; Denis MG; Dréno B J Invest Dermatol; 2014 May; 134(5):1468-1470. PubMed ID: 24025553 [No Abstract] [Full Text] [Related]
19. Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. Wagle N; Emery C; Berger MF; Davis MJ; Sawyer A; Pochanard P; Kehoe SM; Johannessen CM; Macconaill LE; Hahn WC; Meyerson M; Garraway LA J Clin Oncol; 2011 Aug; 29(22):3085-96. PubMed ID: 21383288 [TBL] [Abstract][Full Text] [Related]
20. Comparison of testing methods for the detection of BRAF V600E mutations in malignant melanoma: pre-approval validation study of the companion diagnostic test for vemurafenib. Lopez-Rios F; Angulo B; Gomez B; Mair D; Martinez R; Conde E; Shieh F; Vaks J; Langland R; Lawrence HJ; de Castro DG PLoS One; 2013; 8(1):e53733. PubMed ID: 23326492 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]