BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 20637203)

  • 1. Altered macrophage function contributes to colitis in mice defective in the phosphoinositide-3 kinase subunit p110δ.
    Uno JK; Rao KN; Matsuoka K; Sheikh SZ; Kobayashi T; Li F; Steinbach EC; Sepulveda AR; Vanhaesebroeck B; Sartor RB; Plevy SE
    Gastroenterology; 2010 Nov; 139(5):1642-53, 1653.e1-6. PubMed ID: 20637203
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis.
    Steinbach EC; Kobayashi T; Russo SM; Sheikh SZ; Gipson GR; Kennedy ST; Uno JK; Mishima Y; Borst LB; Liu B; Herfarth H; Ting JP; Sartor RB; Plevy SE
    J Immunol; 2014 Apr; 192(8):3958-68. PubMed ID: 24634494
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphoinositide 3-Kinase P110δ-Signaling Is Critical for Microbiota-Activated IL-10 Production by B Cells that Regulate Intestinal Inflammation.
    Oka A; Mishima Y; Liu B; Herzog JW; Steinbach EC; Kobayashi T; Plevy SE; Sartor RB
    Cells; 2019 Sep; 8(10):. PubMed ID: 31546615
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deficiency of p110δ isoform of the phosphoinositide 3 kinase leads to enhanced resistance to Leishmania donovani.
    Khadem F; Mou Z; Liu D; Varikuti S; Satoskar A; Uzonna JE
    PLoS Negl Trop Dis; 2014 Jun; 8(6):e2951. PubMed ID: 24945303
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of p110δ PI3K prevents inflammatory response and restenosis after artery injury.
    Bilancio A; Rinaldi B; Oliviero MA; Donniacuo M; Monti MG; Boscaino A; Marino I; Friedman L; Rossi F; Vanhaesebroeck B; Migliaccio A
    Biosci Rep; 2017 Oct; 37(5):. PubMed ID: 28851839
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The p110 delta isoform of phosphatidylinositol 3-kinase controls the quality of secondary anti-Leishmania immunity by regulating expansion and effector function of memory T cell subsets.
    Liu D; Uzonna JE
    J Immunol; 2010 Mar; 184(6):3098-105. PubMed ID: 20154209
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphoinositide 3-Kinase (PI3K) Subunit p110δ Is Essential for Trophoblast Cell Differentiation and Placental Development in Mouse.
    Hu X; Li J; Zhang Q; Zheng L; Wang G; Zhang X; Zhang J; Gu Q; Ye Y; Guo SW; Yang X; Wang L
    Sci Rep; 2016 Jun; 6():28201. PubMed ID: 27306493
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PI3K p110δ is expressed by gp38(-)CD31(+) and gp38(+)CD31(+) spleen stromal cells and regulates their CCL19, CCL21, and LTβR mRNA levels.
    Zotes TM; Spada R; Mulens V; Pérez-Yagüe S; Sorzano CO; Okkenhaug K; Carrera AC; Barber DF
    PLoS One; 2013; 8(8):e72960. PubMed ID: 24009720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells.
    Liu D; Zhang T; Marshall AJ; Okkenhaug K; Vanhaesebroeck B; Uzonna JE
    J Immunol; 2009 Aug; 183(3):1921-33. PubMed ID: 19596993
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inactivation of PI3Kδ induces vascular injury and promotes aneurysm development by upregulating the AP-1/MMP-12 pathway in macrophages.
    Zheng L; Xing L; Zeng C; Wu T; Gui Y; Li W; Lan T; Yang Y; Gu Q; Qi C; Zhang Q; Tang F; He X; Wang L
    Arterioscler Thromb Vasc Biol; 2015 Feb; 35(2):368-77. PubMed ID: 25503990
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PI3K p110δ inactivation antagonizes chronic lymphocytic leukemia and reverses T cell immune suppression.
    Dong S; Harrington BK; Hu EY; Greene JT; Lehman AM; Tran M; Wasmuth RL; Long M; Muthusamy N; Brown JR; Johnson AJ; Byrd JC
    J Clin Invest; 2019 Jan; 129(1):122-136. PubMed ID: 30457982
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells.
    Okkenhaug K; Patton DT; Bilancio A; Garçon F; Rowan WC; Vanhaesebroeck B
    J Immunol; 2006 Oct; 177(8):5122-8. PubMed ID: 17015696
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacological inactivation of the PI3K p110δ prevents breast tumour progression by targeting cancer cells and macrophages.
    Goulielmaki E; Bermudez-Brito M; Andreou M; Tzenaki N; Tzardi M; de Bree E; Tsentelierou E; Makrigiannakis A; Papakonstanti EA
    Cell Death Dis; 2018 Jun; 9(6):678. PubMed ID: 29880805
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Paired immunoglobulin-like receptor B (PIR-B) negatively regulates macrophage activation in experimental colitis.
    Munitz A; Cole ET; Beichler A; Groschwitz K; Ahrens R; Steinbrecher K; Willson T; Han X; Denson L; Rothenberg ME; Hogan SP
    Gastroenterology; 2010 Aug; 139(2):530-41. PubMed ID: 20398663
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-kinase p110delta-dependent mechanism.
    Farghaly HS; Blagbrough IS; Medina-Tato DA; Watson ML
    Mol Pharmacol; 2008 May; 73(5):1530-7. PubMed ID: 18276774
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lack of Functional P110δ Affects Expression of Activation Marker CD80 but Does Not Influence Functions of Neutrophils.
    Manda-Handzlik A; Mroczek A; Kuźmicka W; Cieloch A; Homoncik Z; Muchowicz A; Demkow U; Wachowska M
    Int J Mol Sci; 2022 Jun; 23(12):. PubMed ID: 35742807
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages.
    Hamers AA; van Dam L; Teixeira Duarte JM; Vos M; Marinković G; van Tiel CM; Meijer SL; van Stalborch AM; Huveneers S; Te Velde AA; de Jonge WJ; de Vries CJ
    PLoS One; 2015; 10(8):e0133598. PubMed ID: 26241646
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis.
    Lee G; Goretsky T; Managlia E; Dirisina R; Singh AP; Brown JB; May R; Yang GY; Ragheb JW; Evers BM; Weber CR; Turner JR; He XC; Katzman RB; Li L; Barrett TA
    Gastroenterology; 2010 Sep; 139(3):869-81, 881.e1-9. PubMed ID: 20580720
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deficiency of Phosphatidylinositol 3-Kinase δ Signaling Leads to Diminished Numbers of Regulatory T Cells and Increased Neutrophil Activity Resulting in Mortality Due to Endotoxic Shock.
    Okeke EB; Mou Z; Onyilagha N; Jia P; Gounni AS; Uzonna JE
    J Immunol; 2017 Aug; 199(3):1086-1095. PubMed ID: 28659355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ninjurin1 deficiency aggravates colitis development by promoting M1 macrophage polarization and inducing microbial imbalance.
    Choi H; Bae SJ; Choi G; Lee H; Son T; Kim JG; An S; Lee HS; Seo JH; Kwon HB; Jeon S; Oh GT; Surh YJ; Kim KW
    FASEB J; 2020 Jun; 34(6):8702-8720. PubMed ID: 32385864
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.