205 related articles for article (PubMed ID: 20645059)
1. The use of human hepatocytes to investigate drug metabolism and CYP enzyme induction.
Klieber S; Torreilles F; Guillou F; Fabre G
Methods Mol Biol; 2010; 640():295-308. PubMed ID: 20645059
[TBL] [Abstract][Full Text] [Related]
2. Human hepatocytes: isolation, cryopreservation and applications in drug development.
Li AP
Chem Biol Interact; 2007 May; 168(1):16-29. PubMed ID: 17270162
[TBL] [Abstract][Full Text] [Related]
3. The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.
Parkinson A; Mudra DR; Johnson C; Dwyer A; Carroll KM
Toxicol Appl Pharmacol; 2004 Sep; 199(3):193-209. PubMed ID: 15364537
[TBL] [Abstract][Full Text] [Related]
4. Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.
Gómez-Lechón MJ; Castell JV; Donato MT
Chem Biol Interact; 2007 May; 168(1):30-50. PubMed ID: 17134688
[TBL] [Abstract][Full Text] [Related]
5. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
Westerink WM; Schoonen WG
Toxicol In Vitro; 2007 Dec; 21(8):1581-91. PubMed ID: 17637504
[TBL] [Abstract][Full Text] [Related]
6. Cryopreserved human hepatocytes as alternative in vitro model for cytochrome p450 induction studies.
Garcia M; Rager J; Wang Q; Strab R; Hidalgo IJ; Owen A; Li J
In Vitro Cell Dev Biol Anim; 2003; 39(7):283-7. PubMed ID: 14599235
[TBL] [Abstract][Full Text] [Related]
7. HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro.
Lübberstedt M; Müller-Vieira U; Mayer M; Biemel KM; Knöspel F; Knobeloch D; Nüssler AK; Gerlach JC; Zeilinger K
J Pharmacol Toxicol Methods; 2011; 63(1):59-68. PubMed ID: 20460162
[TBL] [Abstract][Full Text] [Related]
8. Use of mRNA expression to detect the induction of drug metabolising enzymes in rat and human hepatocytes.
Richert L; Tuschl G; Abadie C; Blanchard N; Pekthong D; Mantion G; Weber JC; Mueller SO
Toxicol Appl Pharmacol; 2009 Feb; 235(1):86-96. PubMed ID: 19118567
[TBL] [Abstract][Full Text] [Related]
9. Evaluation of 23 lots of commercially available cryopreserved hepatocytes for induction assays of human cytochromes P450.
Yajima K; Uno Y; Murayama N; Uehara S; Shimizu M; Nakamura C; Iwasaki K; Utoh M; Yamazaki H
Drug Metab Dispos; 2014 May; 42(5):867-71. PubMed ID: 24553381
[TBL] [Abstract][Full Text] [Related]
10. The use of hepatocytes to investigate UDP-glucuronosyltransferases and sulfotransferases.
Fournel-Gigleux S; Coughtrie MW; Ouzzine M; Magdalou J
Methods Mol Biol; 2010; 640():309-26. PubMed ID: 20645060
[TBL] [Abstract][Full Text] [Related]
11. Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes.
Roymans D; Annaert P; Van Houdt J; Weygers A; Noukens J; Sensenhauser C; Silva J; Van Looveren C; Hendrickx J; Mannens G; Meuldermans W
Drug Metab Dispos; 2005 Jul; 33(7):1004-16. PubMed ID: 15802389
[TBL] [Abstract][Full Text] [Related]
12. Effect of honokiol on the induction of drug-metabolizing enzymes in human hepatocytes.
Cho YY; Jeong HU; Kim JH; Lee HS
Drug Des Devel Ther; 2014; 8():2137-45. PubMed ID: 25395831
[TBL] [Abstract][Full Text] [Related]
13. In vitro assays for induction of drug metabolism.
Lake BG; Price RJ; Giddings AM; Walters DG
Methods Mol Biol; 2009; 481():47-58. PubMed ID: 19096794
[TBL] [Abstract][Full Text] [Related]
14. The pivotal role of hepatocytes in drug discovery.
Soars MG; McGinnity DF; Grime K; Riley RJ
Chem Biol Interact; 2007 May; 168(1):2-15. PubMed ID: 17208208
[TBL] [Abstract][Full Text] [Related]
15. HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans.
Kanebratt KP; Andersson TB
Drug Metab Dispos; 2008 Jan; 36(1):137-45. PubMed ID: 17954527
[TBL] [Abstract][Full Text] [Related]
16. Clinical versatility of porcine hepatocytes in the light of interspecies differences in cytochrome P450 regulation and expression.
Kleine M; Schrem H; Borlak J; Klempnauer J
Xenotransplantation; 2008; 15(4):208-17. PubMed ID: 18957043
[TBL] [Abstract][Full Text] [Related]
17. Follow-up to the pre-validation of a harmonised protocol for assessment of CYP induction responses in freshly isolated and cryopreserved human hepatocytes with respect to culture format, treatment, positive reference inducers and incubation conditions.
Abadie-Viollon C; Martin H; Blanchard N; Pekthong D; Bachellier P; Mantion G; Heyd B; Schuler F; Coassolo P; Alexandre E; Richert L
Toxicol In Vitro; 2010 Feb; 24(1):346-56. PubMed ID: 19497360
[TBL] [Abstract][Full Text] [Related]
18. Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities.
Doehmer J; Weiss G; McGregor GP; Appel K
Toxicol In Vitro; 2011 Feb; 25(1):21-7. PubMed ID: 20828605
[TBL] [Abstract][Full Text] [Related]
19. The application of HepRG cells in evaluation of cytochrome P450 induction properties of drug compounds.
Andersson TB
Methods Mol Biol; 2010; 640():375-87. PubMed ID: 20645063
[TBL] [Abstract][Full Text] [Related]
20. Metabolic activity of cytochrome p450 isoforms in hepatocytes cryopreserved with wheat protein extract.
Grondin M; Hamel F; Sarhan F; Averill-Bates DA
Drug Metab Dispos; 2008 Oct; 36(10):2121-9. PubMed ID: 18617602
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
