BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 20650183)

  • 1. Reduction of phenoxyl radicals of the antitumour agent etoposide (VP-16) by glutathione and protein sulfhydryls in human leukaemia cells: Implications for cytotoxicity.
    Yalowich JC; Tyurina YY; Tyurin VA; Allan WP; Kagan VE
    Toxicol In Vitro; 1996 Feb; 10(1):59-68. PubMed ID: 20650183
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: protective versus damaging effects of phenolic antioxidants.
    Tyurina YY; Tyurin VA; Yalowich JC; Quinn PJ; Claycamp HG; Schor NF; Pitt BR; Kagan VE
    Toxicol Appl Pharmacol; 1995 Apr; 131(2):277-88. PubMed ID: 7716769
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems.
    Kagan VE; Yalowich JC; Day BW; Goldman R; Gantchev TG; Stoyanovsky DA
    Biochemistry; 1994 Aug; 33(32):9651-60. PubMed ID: 8068642
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tyrosinase-induced phenoxyl radicals of etoposide (VP-16): interaction with reductants in model systems, K562 leukemic cell and nuclear homogenates.
    Stoyanovsky D; Yalowich J; Gantchev T; Kagan V
    Free Radic Res Commun; 1993; 19(6):371-86. PubMed ID: 8168727
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antioxidant paradoxes of phenolic compounds: peroxyl radical scavenger and lipid antioxidant, etoposide (VP-16), inhibits sarcoplasmic reticulum Ca(2+)-ATPase via thiol oxidation by its phenoxyl radical.
    Ritov VB; Goldman R; Stoyanovsky DA; Menshikova EV; Kagan VE
    Arch Biochem Biophys; 1995 Aug; 321(1):140-52. PubMed ID: 7639514
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reversible thiol-dependent activation of ryanodine-sensitive Ca2+ release channel by etoposide (VP-16) phenoxyl radical.
    Fabisiak JP; Ritov VB; Kagan VE
    Antioxid Redox Signal; 2000; 2(1):73-82. PubMed ID: 11232603
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of Na+/K(+)-ATPase by phenoxyl radicals of etoposide (VP-16): role of sulfhydryls oxidation.
    Kurella EG; Osipov AN; Goldman R; Boldyrev AA; Kagan VE
    Biochim Biophys Acta; 1995 Nov; 1232(1-2):52-8. PubMed ID: 7495837
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: free radical/antioxidant approach.
    Kagan VE; Yalowich JC; Borisenko GG; Tyurina YY; Tyurin VA; Thampatty P; Fabisiak JP
    Mol Pharmacol; 1999 Sep; 56(3):494-506. PubMed ID: 10462537
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase.
    Kagan VE; Kuzmenko AI; Tyurina YY; Shvedova AA; Matsura T; Yalowich JC
    Cancer Res; 2001 Nov; 61(21):7777-84. PubMed ID: 11691792
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phenoxyl radical-induced thiol-dependent generation of reactive oxygen species: implications for benzene toxicity.
    Stoyanovsky DA; Goldman R; Claycamp HG; Kagan VE
    Arch Biochem Biophys; 1995 Mar; 317(2):315-23. PubMed ID: 7893144
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells.
    Kagan VE; Kuzmenko AI; Shvedova AA; Kisin ER; Li R; Martin I; Quinn PJ; Tyurin VA; Tyurina YY; Yalowich JC
    Biochim Biophys Acta; 2003 Mar; 1620(1-3):72-84. PubMed ID: 12595076
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recycling and redox cycling of phenolic antioxidants.
    Kagan VE; Tyurina YY
    Ann N Y Acad Sci; 1998 Nov; 854():425-34. PubMed ID: 9928449
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhancement of etoposide (VP-16) cytotoxicity by enzymatic and photodynamically induced oxidative stress.
    Gantchev TG; Hunting DJ
    Anticancer Drugs; 1997 Feb; 8(2):164-73. PubMed ID: 9073312
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Myeloperoxidase-catalyzed redox-cycling of phenol promotes lipid peroxidation and thiol oxidation in HL-60 cells.
    Goldman R; Claycamp GH; Sweetland MA; Sedlov AV; Tyurin VA; Kisin ER; Tyurina YY; Ritov VB; Wenger SL; Grant SG; Kagan VE
    Free Radic Biol Med; 1999 Nov; 27(9-10):1050-63. PubMed ID: 10569638
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ascorbate interacts with reduced glutathione to scavenge phenoxyl radicals in HL60 cells.
    Cuddihy SL; Parker A; Harwood DT; Vissers MC; Winterbourn CC
    Free Radic Biol Med; 2008 Apr; 44(8):1637-44. PubMed ID: 18291121
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid.
    Stoyanovsky DA; Goldman R; Darrow RM; Organisciak DT; Kagan VE
    Curr Eye Res; 1995 Mar; 14(3):181-9. PubMed ID: 7796601
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reactions of phenoxyl radicals with NADPH-cytochrome P-450 oxidoreductase and NADPH: reduction of the radicals and inhibition of the enzyme.
    Goldman R; Tsyrlov IB; Grogan J; Kagan VE
    Biochemistry; 1997 Mar; 36(11):3186-92. PubMed ID: 9115995
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interactions of the antitumor drug, etoposide, with reduced thiols in vitro and in vivo.
    Katki AG; Kalyanaraman B; Sinha BK
    Chem Biol Interact; 1987; 62(3):237-47. PubMed ID: 3040275
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Peroxidase-catalyzed oxidation of beta-carotene in HL-60 cells and in model systems: involvement of phenoxyl radicals.
    Tyurin VA; Carta G; Tyurina YY; Banni S; Day BW; Corongiu FP; Kagan VE
    Lipids; 1997 Feb; 32(2):131-42. PubMed ID: 9075202
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Redox cycling of phenol induces oxidative stress in human epidermal keratinocytes.
    Shvedova AA; Kommineni C; Jeffries BA; Castranova V; Tyurina YY; Tyurin VA; Serbinova EA; Fabisiak JP; Kagan VE
    J Invest Dermatol; 2000 Feb; 114(2):354-64. PubMed ID: 10651998
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.