BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

415 related articles for article (PubMed ID: 20656495)

  • 1. Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles.
    Samadi A; Marco-Contelles J; Soriano E; Alvarez-Pérez M; Chioua M; Romero A; González-Lafuente L; Gandía L; Roda JM; López MG; Villarroya M; García AG; Ríos Cde L
    Bioorg Med Chem; 2010 Aug; 18(16):5861-72. PubMed ID: 20656495
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3-carbonitriles.
    Samadi A; Valderas C; de los Ríos C; Bastida A; Chioua M; González-Lafuente L; Colmena I; Gandía L; Romero A; Del Barrio L; Martín-de-Saavedra MD; López MG; Villarroya M; Marco-Contelles J
    Bioorg Med Chem; 2011 Jan; 19(1):122-33. PubMed ID: 21163662
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: synthesis, biological assessment, and molecular modeling.
    Samadi A; Estrada M; Pérez C; Rodríguez-Franco MI; Iriepa I; Moraleda I; Chioua M; Marco-Contelles J
    Eur J Med Chem; 2012 Nov; 57():296-301. PubMed ID: 23078965
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease.
    Maalej E; Chabchoub F; Oset-Gasque MJ; Esquivias-Pérez M; González MP; Monjas L; Pérez C; de los Ríos C; Rodríguez-Franco MI; Iriepa I; Moraleda I; Chioua M; Romero A; Marco-Contelles J; Samadi A
    Eur J Med Chem; 2012 Aug; 54():750-63. PubMed ID: 22795665
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.
    de Los Ríos C; Egea J; Marco-Contelles J; León R; Samadi A; Iriepa I; Moraleda I; Gálvez E; García AG; López MG; Villarroya M; Romero A
    J Med Chem; 2010 Jul; 53(14):5129-43. PubMed ID: 20575555
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer's disease.
    Samadi A; Chioua M; Bolea I; de Los Ríos C; Iriepa I; Moraleda I; Bastida A; Esteban G; Unzeta M; Gálvez E; Marco-Contelles J
    Eur J Med Chem; 2011 Sep; 46(9):4665-8. PubMed ID: 21669479
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine.
    Samadi A; de los Ríos C; Bolea I; Chioua M; Iriepa I; Moraleda I; Bartolini M; Andrisano V; Gálvez E; Valderas C; Unzeta M; Marco-Contelles J
    Eur J Med Chem; 2012 Jun; 52():251-62. PubMed ID: 22503231
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties.
    Fernández-Bachiller MI; Pérez C; Campillo NE; Páez JA; González-Muñoz GC; Usán P; García-Palomero E; López MG; Villarroya M; García AG; Martínez A; Rodríguez-Franco MI
    ChemMedChem; 2009 May; 4(5):828-41. PubMed ID: 19308922
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New multipotent tetracyclic tacrines with neuroprotective activity.
    Marco-Contelles J; León R; de los Ríos C; García AG; López MG; Villarroya M
    Bioorg Med Chem; 2006 Dec; 14(24):8176-85. PubMed ID: 17005406
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase.
    Huang L; Luo Z; He F; Lu J; Li X
    Bioorg Med Chem; 2010 Jun; 18(12):4475-84. PubMed ID: 20471843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
    Arce MP; Rodríguez-Franco MI; González-Muñoz GC; Pérez C; López B; Villarroya M; López MG; García AG; Conde S
    J Med Chem; 2009 Nov; 52(22):7249-57. PubMed ID: 19856923
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
    Shaik JB; Palaka BK; Penumala M; Kotapati KV; Devineni SR; Eadlapalli S; Darla MM; Ampasala DR; Vadde R; Amooru GD
    Eur J Med Chem; 2016 Jan; 107():219-32. PubMed ID: 26588065
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors.
    Huang L; Shi A; He F; Li X
    Bioorg Med Chem; 2010 Feb; 18(3):1244-51. PubMed ID: 20056426
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, pharmacological assessment, and molecular modeling of 6-chloro-pyridonepezils: new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease.
    Samadi A; de la Fuente Revenga M; Pérez C; Iriepa I; Moraleda I; Rodríguez-Franco MI; Marco-Contelles J
    Eur J Med Chem; 2013 Sep; 67():64-74. PubMed ID: 23838422
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, Synthesis, and Molecular Docking of Some Novel Tacrine Based Cyclopentapyranopyridine- and Tetrahydropyranoquinoline-Kojic Acid Derivatives as Anti-Acetylcholinesterase Agents.
    Babaee S; Chehardoli G; Akbarzadeh T; Zolfigol MA; Mahdavi M; Rastegari A; Homayouni Moghadam F; Najafi Z
    Chem Biodivers; 2021 Jun; 18(6):e2000924. PubMed ID: 33861892
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I; Juárez-Jiménez J; de Los Ríos C; Chioua M; Pouplana R; Luque FJ; Unzeta M; Marco-Contelles J; Samadi A
    J Med Chem; 2011 Dec; 54(24):8251-70. PubMed ID: 22023459
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties.
    León R; de los Ríos C; Marco-Contelles J; Huertas O; Barril X; Luque FJ; López MG; García AG; Villarroya M
    Bioorg Med Chem; 2008 Aug; 16(16):7759-69. PubMed ID: 18640842
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
    Maqbool M; Manral A; Jameel E; Kumar J; Saini V; Shandilya A; Tiwari M; Hoda N; Jayaram B
    Bioorg Med Chem; 2016 Jun; 24(12):2777-88. PubMed ID: 27157006
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel Pyridine-Containing Sultones: Structure-Activity Relationship and Biological Evaluation as Selective AChE Inhibitors for the Treatment of Alzheimer's disease.
    Zhang H; Wu C; Chen X; Zhang Z; Jiang X; Qin HL; Tang W
    ChemMedChem; 2021 Oct; 16(20):3189-3200. PubMed ID: 34036731
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, biological assessment and molecular modeling of 14-aryl-10,11,12,14-tetrahydro-9H-benzo[5,6]chromeno[2,3-b]quinolin-13-amines.
    Maalej E; Chabchoub F; Samadi A; de los Ríos C; Perona A; Morreale A; Marco-Contelles J
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2384-8. PubMed ID: 21411323
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.