BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 20659584)

  • 1. Prevention by L-carnitine of DNA damage induced by propionic and L-methylmalonic acids in human peripheral leukocytes in vitro.
    Ribas GS; Manfredini V; de Marco MG; Vieira RB; Wayhs CY; Vanzin CS; Biancini GB; Wajner M; Vargas CR
    Mutat Res; 2010 Sep; 702(1):123-8. PubMed ID: 20659584
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prevention of DNA damage by L-carnitine induced by metabolites accumulated in maple syrup urine disease in human peripheral leukocytes in vitro.
    Mescka CP; Wayhs CA; Guerreiro G; Manfredini V; Dutra-Filho CS; Vargas CR
    Gene; 2014 Sep; 548(2):294-8. PubMed ID: 25046137
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biochemical and anaplerotic applications of in vitro models of propionic acidemia and methylmalonic acidemia using patient-derived primary hepatocytes.
    Collado MS; Armstrong AJ; Olson M; Hoang SA; Day N; Summar M; Chapman KA; Reardon J; Figler RA; Wamhoff BR
    Mol Genet Metab; 2020 Jul; 130(3):183-196. PubMed ID: 32451238
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxidative stress parameters in urine from patients with disorders of propionate metabolism: a beneficial effect of L:-carnitine supplementation.
    Ribas GS; Biancini GB; Mescka C; Wayhs CY; Sitta A; Wajner M; Vargas CR
    Cell Mol Neurobiol; 2012 Jan; 32(1):77-82. PubMed ID: 21833551
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ganglioside alterations in the central nervous system of rats chronically injected with methylmalonic and propionic acids.
    Trindade VM; Brusque AM; Raasch JR; Pettenuzzo LE; Rocha HP; Wannmacher CM; Wajne M
    Metab Brain Dis; 2002 Jun; 17(2):93-102. PubMed ID: 12083341
    [TBL] [Abstract][Full Text] [Related]  

  • 6. L-Carnitine supplementation decreases DNA damage in treated MSUD patients.
    Mescka CP; Guerreiro G; Hammerschmidt T; Faverzani J; de Moura Coelho D; Mandredini V; Wayhs CA; Wajner M; Dutra-Filho CS; Vargas CR
    Mutat Res; 2015 May; 775():43-7. PubMed ID: 25867118
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Experimental evidence of oxidative stress in patients with l-2-hydroxyglutaric aciduria and that l-carnitine attenuates in vitro DNA damage caused by d-2-hydroxyglutaric and l-2-hydroxyglutaric acids.
    Rodrigues DGB; de Moura Coelho D; Sitta Â; Jacques CED; Hauschild T; Manfredini V; Bakkali A; Struys EA; Jakobs C; Wajner M; Vargas CR
    Toxicol In Vitro; 2017 Aug; 42():47-53. PubMed ID: 28396261
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evidence that DNA damage is associated to phenylalanine blood levels in leukocytes from phenylketonuric patients.
    Sitta A; Manfredini V; Biasi L; Treméa R; Schwartz IV; Wajner M; Vargas CR
    Mutat Res; 2009; 679(1-2):13-6. PubMed ID: 19665577
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolism of 1-13C-propionate in vivo in patients with disorders of propionate metabolism.
    Barshop BA; Yoshida I; Ajami A; Sweetman L; Wolff JA; Sweetman FR; Prodanos C; Smith M; Nyhan WL
    Pediatr Res; 1991 Jul; 30(1):15-22. PubMed ID: 1909779
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of long-term effectiveness of the use of carglumic acid in patients with propionic acidemia (PA) or methylmalonic acidemia (MMA): study protocol for a randomized controlled trial.
    Nashabat M; Obaid A; Al Mutairi F; Saleh M; Elamin M; Ahmed H; Ababneh F; Eyaid W; Alswaid A; Alohali L; Faqeih E; Aljeraisy M; Hussein MA; Alasmari A; Alfadhel M
    BMC Pediatr; 2019 Jun; 19(1):195. PubMed ID: 31196016
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduction of lipid and protein damage in patients with disorders of propionate metabolism under treatment: a possible protective role of L-carnitine supplementation.
    Ribas GS; Manfredini V; de Mari JF; Wayhs CY; Vanzin CS; Biancini GB; Sitta A; Deon M; Wajner M; Vargas CR
    Int J Dev Neurosci; 2010 Apr; 28(2):127-32. PubMed ID: 20100562
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prevention by L-carnitine of DNA damage induced by 3-hydroxy-3-methylglutaric and 3-methylglutaric acids and experimental evidence of lipid and DNA damage in patients with 3-hydroxy-3-methylglutaric aciduria.
    Delgado CA; Balbueno Guerreiro GB; Diaz Jacques CE; de Moura Coelho D; Sitta A; Manfredini V; Wajner M; Vargas CR
    Arch Biochem Biophys; 2019 Jun; 668():16-22. PubMed ID: 31047871
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stabilization of blood methylmalonic acid level in methylmalonic acidemia after liver transplantation.
    Chen PW; Hwu WL; Ho MC; Lee NC; Chien YH; Ni YH; Lee PH
    Pediatr Transplant; 2010 May; 14(3):337-41. PubMed ID: 19686300
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Experimental evidence that methylmalonic acid provokes oxidative damage and compromises antioxidant defenses in nerve terminal and striatum of young rats.
    Fernandes CG; Borges CG; Seminotti B; Amaral AU; Knebel LA; Eichler P; de Oliveira AB; Leipnitz G; Wajner M
    Cell Mol Neurobiol; 2011 Jul; 31(5):775-85. PubMed ID: 21424830
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Analysis of propionylcarnitine in blood and methylmalonic acid in urine of 162 patients with methylmalonic acidemia].
    Wu SN; Han LS; Ye J; Qiu WJ; Zhang HW; Gao XL; Wang Y; Li XY; Xu H; Gu XF
    Zhonghua Yi Xue Za Zhi; 2013 Feb; 93(8):561-5. PubMed ID: 23663331
    [TBL] [Abstract][Full Text] [Related]  

  • 16. L-carnitine in inborn errors of metabolism: what is the evidence?
    Walter JH
    J Inherit Metab Dis; 2003; 26(2-3):181-8. PubMed ID: 12889659
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biomarkers for drug development in propionic and methylmalonic acidemias.
    Longo N; Sass JO; Jurecka A; Vockley J
    J Inherit Metab Dis; 2022 Mar; 45(2):132-143. PubMed ID: 35038174
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oxidative damage in mitochondrial fatty acids oxidation disorders patients and the in vitro effect of l-carnitine on DNA damage induced by the accumulated metabolites.
    de Moraes MS; Guerreiro G; Sitta A; de Moura Coelho D; Manfredini V; Wajner M; Vargas CR
    Arch Biochem Biophys; 2020 Jan; 679():108206. PubMed ID: 31760122
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of mitochondrial creatine kinase activity from rat cerebral cortex by methylmalonic acid.
    Schuck PF; Rosa RB; Pettenuzzo LF; Sitta A; Wannmacher CM; Wyse AT; Wajner M
    Neurochem Int; 2004 Oct; 45(5):661-7. PubMed ID: 15234108
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Studies on the beneficial effect of levocarnitine chloride (LC-80) on organic acidemias, especially propionic acidemia and methylmalonic acidemia].
    Fujisawa S; Shimatani K; Yamada H; Hironaka Y
    Nihon Yakurigaku Zasshi; 1989 May; 93(5):305-14. PubMed ID: 2744657
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.