BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 20669972)

  • 1. Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton.
    Mwakwari SC; Guerrant W; Patil V; Khan SI; Tekwani BL; Gurard-Levin ZA; Mrksich M; Oyelere AK
    J Med Chem; 2010 Aug; 53(16):6100-11. PubMed ID: 20669972
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors.
    Sodji Q; Patil V; Jain S; Kornacki JR; Mrksich M; Tekwani BL; Oyelere AK
    Bioorg Med Chem Lett; 2014 Oct; 24(20):4826-30. PubMed ID: 25240614
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A series of potent and selective, triazolylphenyl-based histone deacetylases inhibitors with activity against pancreatic cancer cells and Plasmodium falciparum.
    Chen Y; Lopez-Sanchez M; Savoy DN; Billadeau DD; Dow GS; Kozikowski AP
    J Med Chem; 2008 Jun; 51(12):3437-48. PubMed ID: 18494463
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of a potent histone deacetylase (HDAC) 3/6 selective dual inhibitor.
    Soumyanarayanan U; Ramanujulu PM; Mustafa N; Haider S; Fang Nee AH; Tong JX; Tan KSW; Chng WJ; Dymock BW
    Eur J Med Chem; 2019 Dec; 184():111755. PubMed ID: 31627059
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Macrocyclic histone deacetylase inhibitors.
    Mwakwari SC; Patil V; Guerrant W; Oyelere AK
    Curr Top Med Chem; 2010; 10(14):1423-40. PubMed ID: 20536416
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Non-peptide macrocyclic histone deacetylase inhibitors.
    Oyelere AK; Chen PC; Guerrant W; Mwakwari SC; Hood R; Zhang Y; Fan Y
    J Med Chem; 2009 Jan; 52(2):456-68. PubMed ID: 19093884
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.
    Hansen FK; Skinner-Adams TS; Duffy S; Marek L; Sumanadasa SD; Kuna K; Held J; Avery VM; Andrews KT; Kurz T
    ChemMedChem; 2014 Mar; 9(3):665-70. PubMed ID: 24497437
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and Synthesis of Novel Anti-Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit.
    Alves Avelar LA; Held J; Engel JA; Sureechatchaiyan P; Hansen FK; Hamacher A; Kassack MU; Mordmüller B; Andrews KT; Kurz T
    Arch Pharm (Weinheim); 2017 Apr; 350(3-4):. PubMed ID: 28317157
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of class I histone deacetylase inhibitors based on romidpesin with promising selectivity for cancer cells.
    Zhang K; Yao Y; Tu Z; Liao C; Wang Z; Qiu Y; Chen D; Hamilton DJ; Li Z; Jiang S
    Future Med Chem; 2020 Feb; 12(4):311-323. PubMed ID: 31782319
    [No Abstract]   [Full Text] [Related]  

  • 10. A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities.
    Tapadar S; Fathi S; Raji I; Omesiete W; Kornacki JR; Mwakwari SC; Miyata M; Mitsutake K; Li JD; Mrksich M; Oyelere AK
    Bioorg Med Chem; 2015 Dec; 23(24):7543-64. PubMed ID: 26585275
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.
    Patil V; Guerrant W; Chen PC; Gryder B; Benicewicz DB; Khan SI; Tekwani BL; Oyelere AK
    Bioorg Med Chem; 2010 Jan; 18(1):415-25. PubMed ID: 19914074
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages.
    Hansen FK; Sumanadasa SD; Stenzel K; Duffy S; Meister S; Marek L; Schmetter R; Kuna K; Hamacher A; Mordmüller B; Kassack MU; Winzeler EA; Avery VM; Andrews KT; Kurz T
    Eur J Med Chem; 2014 Jul; 82():204-13. PubMed ID: 24904967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and Investigation of Therapeutic Potential of Isoform-Specific HDAC8 Inhibitors for the Treatment of Cutaneous T Cell Lymphoma.
    Umamaheswari A; Puratchikody A; Hari N
    Anticancer Agents Med Chem; 2019; 19(7):916-934. PubMed ID: 30836926
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity.
    Wu B; Fathi S; Mortley S; Mohiuddin M; Jang YC; Oyelere AK
    Bioorg Med Chem; 2020 Mar; 28(6):115345. PubMed ID: 32061484
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, Synthesis and Biological Evaluation of Novel N-hydroxyheptanamides Incorporating 6-hydroxy-2-methylquinazolin-4(3H)-ones as Histone Deacetylase Inhibitors and Cytotoxic Agents.
    Minh NV; Thanh NT; Lien HT; Anh DTP; Cuong HD; Nam NH; Hai PT; Minh-Ngoc L; Le-Thi-Thu H; Chinh LV; Vu TK
    Anticancer Agents Med Chem; 2019; 19(12):1543-1557. PubMed ID: 31267876
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel chimeric histone deacetylase inhibitors: a series of lapatinib hybrides as potent inhibitors of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and histone deacetylase activity.
    Mahboobi S; Sellmer A; Winkler M; Eichhorn E; Pongratz H; Ciossek T; Baer T; Maier T; Beckers T
    J Med Chem; 2010 Dec; 53(24):8546-55. PubMed ID: 21080629
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of novel hydroxamates and 2-aminobenzamides as potent histone deacetylase inhibitors and antitumor agents.
    Xie R; Yao Y; Tang P; Chen G; Liu X; Yun F; Cheng C; Wu X; Yuan Q
    Eur J Med Chem; 2017 Jul; 134():1-12. PubMed ID: 28391133
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents.
    Xie R; Li Y; Tang P; Yuan Q
    Eur J Med Chem; 2018 Jan; 143():320-333. PubMed ID: 29202397
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A structure-activity relationship study of the antimalarial and antileishmanial activities of nonpeptide macrocyclic histone deacetylase inhibitors.
    Guerrant W; Mwakwari SC; Chen PC; Khan SI; Tekwani BL; Oyelere AK
    ChemMedChem; 2010 Aug; 5(8):1232-5. PubMed ID: 20533500
    [No Abstract]   [Full Text] [Related]  

  • 20. Progress in the Discovery of Macrocyclic Histone Deacetylase Inhibitors for the Treatment of Cancer.
    Cheng K; Li S; Liao C
    Curr Med Chem; 2017; 24(37):4166-4179. PubMed ID: 28183258
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.