These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 20670938)

  • 1. Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.
    Li C; Chen P; Palladino A; Narayan S; Russell LK; Sayed S; Xiong G; Chen J; Stokes D; Butt YM; Jones PM; Collins HW; Cohen NA; Cohen AS; Nissim I; Smith TJ; Strauss AW; Matschinsky FM; Bennett MJ; Stanley CA
    J Biol Chem; 2010 Oct; 285(41):31806-18. PubMed ID: 20670938
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid-sensitive hypoglycemia.
    St-Louis JL; El Jellas K; Velasco K; Slipp BA; Hu J; Helgeland G; Steine SJ; De Jesus DF; Kulkarni RN; Molven A
    J Biol Chem; 2023 Aug; 299(8):104986. PubMed ID: 37392854
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Leucine-sensitive hyperinsulinaemic hypoglycaemia in patients with loss of function mutations in 3-Hydroxyacyl-CoA Dehydrogenase.
    Heslegrave AJ; Kapoor RR; Eaton S; Chadefaux B; Akcay T; Simsek E; Flanagan SE; Ellard S; Hussain K
    Orphanet J Rare Dis; 2012 May; 7():25. PubMed ID: 22583614
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional evaluation of 16 SCHAD missense variants: Only amino acid substitutions causing congenital hyperinsulinism of infancy lead to loss-of-function phenotypes in vitro.
    Velasco K; St-Louis JL; Hovland HN; Thompson N; Ottesen Å; Choi MH; Pedersen L; Njølstad PR; Arnesen T; Fjeld K; Aukrust I; Myklebust LM; Molven A
    J Inherit Metab Dis; 2021 Jan; 44(1):240-252. PubMed ID: 32876354
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel insights into fatty acid oxidation, amino acid metabolism, and insulin secretion from studying patients with loss of function mutations in 3-hydroxyacyl-CoA dehydrogenase.
    Heslegrave AJ; Hussain K
    J Clin Endocrinol Metab; 2013 Feb; 98(2):496-501. PubMed ID: 23253615
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.
    Grimaldi M; Karaca M; Latini L; Brioudes E; Schalch T; Maechler P
    Hum Mol Genet; 2017 Sep; 26(18):3453-3465. PubMed ID: 28911206
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of medium- and short-chain L-3-hydroxyacyl-CoA dehydrogenase in the regulation of body weight and thermogenesis.
    Schulz N; Himmelbauer H; Rath M; van Weeghel M; Houten S; Kulik W; Suhre K; Scherneck S; Vogel H; Kluge R; Wiedmer P; Joost HG; Schürmann A
    Endocrinology; 2011 Dec; 152(12):4641-51. PubMed ID: 21990309
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase.
    Stanley CA
    Neurochem Int; 2011 Sep; 59(4):465-72. PubMed ID: 21130127
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glutaminolysis and insulin secretion: from bedside to bench and back.
    Kelly A; Li C; Gao Z; Stanley CA; Matschinsky FM
    Diabetes; 2002 Dec; 51 Suppl 3():S421-6. PubMed ID: 12475785
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with hyperinsulinism: a novel glucose-fatty acid cycle?
    Eaton S; Chatziandreou I; Krywawych S; Pen S; Clayton PT; Hussain K
    Biochem Soc Trans; 2003 Dec; 31(Pt 6):1137-9. PubMed ID: 14641012
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion.
    Clayton PT; Eaton S; Aynsley-Green A; Edginton M; Hussain K; Krywawych S; Datta V; Malingre HE; Berger R; van den Berg IE
    J Clin Invest; 2001 Aug; 108(3):457-65. PubMed ID: 11489939
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of a GTP-insensitive mutation of glutamate dehydrogenase on insulin secretion in transgenic mice.
    Li C; Matter A; Kelly A; Petty TJ; Najafi H; MacMullen C; Daikhin Y; Nissim I; Lazarow A; Kwagh J; Collins HW; Hsu BY; Nissim I; Yudkoff M; Matschinsky FM; Stanley CA
    J Biol Chem; 2006 Jun; 281(22):15064-72. PubMed ID: 16574664
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Hypoglycemic Phenotype Is Islet Cell-Autonomous in Short-Chain Hydroxyacyl-CoA Dehydrogenase-Deficient Mice.
    Molven A; Hollister-Lock J; Hu J; Martinez R; Njølstad PR; Liew CW; Weir G; Kulkarni RN
    Diabetes; 2016 Jun; 65(6):1672-8. PubMed ID: 26953163
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of short-chain hydroxyacyl CoA dehydrogenases in SCHAD deficiency.
    Filling C; Keller B; Hirschberg D; Marschall HU; Jörnvall H; Bennett MJ; Oppermann U
    Biochem Biophys Res Commun; 2008 Mar; 368(1):6-11. PubMed ID: 18036338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.
    Vetterli L; Carobbio S; Pournourmohammadi S; Martin-Del-Rio R; Skytt DM; Waagepetersen HS; Tamarit-Rodriguez J; Maechler P
    Mol Biol Cell; 2012 Oct; 23(19):3851-62. PubMed ID: 22875990
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets.
    Carobbio S; Ishihara H; Fernandez-Pascual S; Bartley C; Martin-Del-Rio R; Maechler P
    Diabetologia; 2004 Feb; 47(2):266-76. PubMed ID: 14689183
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of glutamate metabolism and insulin secretion by glutamate dehydrogenase in hypoglycemic children.
    Stanley CA
    Am J Clin Nutr; 2009 Sep; 90(3):862S-866S. PubMed ID: 19625687
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Familial hyperinsulinemic hypoglycemia caused by a defect in the SCHAD enzyme of mitochondrial fatty acid oxidation.
    Molven A; Matre GE; Duran M; Wanders RJ; Rishaug U; Njølstad PR; Jellum E; Søvik O
    Diabetes; 2004 Jan; 53(1):221-7. PubMed ID: 14693719
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase.
    Tanizawa Y; Nakai K; Sasaki T; Anno T; Ohta Y; Inoue H; Matsuo K; Koga M; Furukawa S; Oka Y
    Diabetes; 2002 Mar; 51(3):712-7. PubMed ID: 11872671
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of amino acid-stimulated insulin secretion in congenital hyperinsulinism.
    Zhang T; Li C
    Acta Biochim Biophys Sin (Shanghai); 2013 Jan; 45(1):36-43. PubMed ID: 23212075
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.