BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

434 related articles for article (PubMed ID: 20674093)

  • 1. Nuclear localization sequence of FUS and induction of stress granules by ALS mutants.
    Gal J; Zhang J; Kwinter DM; Zhai J; Jia H; Jia J; Zhu H
    Neurobiol Aging; 2011 Dec; 32(12):2323.e27-40. PubMed ID: 20674093
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
    Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
    Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.
    Vance C; Scotter EL; Nishimura AL; Troakes C; Mitchell JC; Kathe C; Urwin H; Manser C; Miller CC; Hortobágyi T; Dragunow M; Rogelj B; Shaw CE
    Hum Mol Genet; 2013 Jul; 22(13):2676-88. PubMed ID: 23474818
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Autophagy regulates amyotrophic lateral sclerosis-linked fused in sarcoma-positive stress granules in neurons.
    Ryu HH; Jun MH; Min KJ; Jang DJ; Lee YS; Kim HK; Lee JA
    Neurobiol Aging; 2014 Dec; 35(12):2822-2831. PubMed ID: 25216585
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations.
    Tradewell ML; Yu Z; Tibshirani M; Boulanger MC; Durham HD; Richard S
    Hum Mol Genet; 2012 Jan; 21(1):136-49. PubMed ID: 21965298
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.
    Dormann D; Rodde R; Edbauer D; Bentmann E; Fischer I; Hruscha A; Than ME; Mackenzie IR; Capell A; Schmid B; Neumann M; Haass C
    EMBO J; 2010 Aug; 29(16):2841-57. PubMed ID: 20606625
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
    Daigle JG; Lanson NA; Smith RB; Casci I; Maltare A; Monaghan J; Nichols CD; Kryndushkin D; Shewmaker F; Pandey UB
    Hum Mol Genet; 2013 Mar; 22(6):1193-205. PubMed ID: 23257289
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aggregation of ALS-linked FUS mutant sequesters RNA binding proteins and impairs RNA granules formation.
    Takanashi K; Yamaguchi A
    Biochem Biophys Res Commun; 2014 Sep; 452(3):600-7. PubMed ID: 25173930
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ALS-Related Mutant FUS Protein Is Mislocalized to Cytoplasm and Is Recruited into Stress Granules of Fibroblasts from Asymptomatic FUS P525L Mutation Carriers.
    Lo Bello M; Di Fini F; Notaro A; Spataro R; Conforti FL; La Bella V
    Neurodegener Dis; 2017; 17(6):292-303. PubMed ID: 29035885
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.
    Verbeeck C; Deng Q; Dejesus-Hernandez M; Taylor G; Ceballos-Diaz C; Kocerha J; Golde T; Das P; Rademakers R; Dickson DW; Kukar T
    Mol Neurodegener; 2012 Oct; 7():53. PubMed ID: 23046583
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
    Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
    Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis.
    Tyzack GE; Luisier R; Taha DM; Neeves J; Modic M; Mitchell JS; Meyer I; Greensmith L; Newcombe J; Ule J; Luscombe NM; Patani R
    Brain; 2019 Sep; 142(9):2572-2580. PubMed ID: 31368485
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS).
    Zhang ZC; Chook YM
    Proc Natl Acad Sci U S A; 2012 Jul; 109(30):12017-21. PubMed ID: 22778397
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
    Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A
    Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS.
    Ito D; Suzuki N
    Neurology; 2011 Oct; 77(17):1636-43. PubMed ID: 21956718
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis.
    Shelkovnikova TA; An H; Skelt L; Tregoning JS; Humphreys IR; Buchman VL
    Cell Rep; 2019 Dec; 29(13):4496-4508.e4. PubMed ID: 31875556
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics.
    Baron DM; Kaushansky LJ; Ward CL; Sama RR; Chian RJ; Boggio KJ; Quaresma AJ; Nickerson JA; Bosco DA
    Mol Neurodegener; 2013 Aug; 8():30. PubMed ID: 24090136
    [TBL] [Abstract][Full Text] [Related]  

  • 18. U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish.
    Yu Y; Chi B; Xia W; Gangopadhyay J; Yamazaki T; Winkelbauer-Hurt ME; Yin S; Eliasse Y; Adams E; Shaw CE; Reed R
    Nucleic Acids Res; 2015 Mar; 43(6):3208-18. PubMed ID: 25735748
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effect of PRMT1-mediated arginine methylation on the subcellular localization, stress granules, and detergent-insoluble aggregates of FUS/TLS.
    Yamaguchi A; Kitajo K
    PLoS One; 2012; 7(11):e49267. PubMed ID: 23152885
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis-FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS inclusions.
    Troakes C; Hortobágyi T; Vance C; Al-Sarraj S; Rogelj B; Shaw CE
    Neuropathol Appl Neurobiol; 2013 Aug; 39(5):553-61. PubMed ID: 22934812
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.