202 related articles for article (PubMed ID: 20675402)
1. Bag1 directly routes immature BCR-ABL for proteasomal degradation.
Tsukahara F; Maru Y
Blood; 2010 Nov; 116(18):3582-92. PubMed ID: 20675402
[TBL] [Abstract][Full Text] [Related]
2. Oridonin Triggers Chaperon-mediated Proteasomal Degradation of BCR-ABL in Leukemia.
Huang H; Weng H; Dong B; Zhao P; Zhou H; Qu L
Sci Rep; 2017 Jan; 7():41525. PubMed ID: 28128329
[TBL] [Abstract][Full Text] [Related]
3. The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity.
Paul I; Ahmed SF; Bhowmik A; Deb S; Ghosh MK
Oncogene; 2013 Mar; 32(10):1284-95. PubMed ID: 22543587
[TBL] [Abstract][Full Text] [Related]
4. Ca2+/S100 proteins act as upstream regulators of the chaperone-associated ubiquitin ligase CHIP (C terminus of Hsc70-interacting protein).
Shimamoto S; Kubota Y; Yamaguchi F; Tokumitsu H; Kobayashi R
J Biol Chem; 2013 Mar; 288(10):7158-68. PubMed ID: 23344957
[TBL] [Abstract][Full Text] [Related]
5. Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3.
George P; Bali P; Annavarapu S; Scuto A; Fiskus W; Guo F; Sigua C; Sondarva G; Moscinski L; Atadja P; Bhalla K
Blood; 2005 Feb; 105(4):1768-76. PubMed ID: 15514006
[TBL] [Abstract][Full Text] [Related]
6. Disruption of the Bcr-Abl/Hsp90 protein complex: a possible mechanism to inhibit Bcr-Abl-positive human leukemic blasts by novobiocin.
Wu LX; Xu JH; Zhang KZ; Lin Q; Huang XW; Wen CX; Chen YZ
Leukemia; 2008 Jul; 22(7):1402-9. PubMed ID: 18418407
[TBL] [Abstract][Full Text] [Related]
7. As4S4 targets RING-type E3 ligase c-CBL to induce degradation of BCR-ABL in chronic myelogenous leukemia.
Mao JH; Sun XY; Liu JX; Zhang QY; Liu P; Huang QH; Li KK; Chen Q; Chen Z; Chen SJ
Proc Natl Acad Sci U S A; 2010 Dec; 107(50):21683-8. PubMed ID: 21118980
[TBL] [Abstract][Full Text] [Related]
8. Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase.
Xia T; Dimitropoulou C; Zeng J; Antonova GN; Snead C; Venema RC; Fulton D; Qian S; Patterson C; Papapetropoulos A; Catravas JD
Am J Physiol Heart Circ Physiol; 2007 Nov; 293(5):H3080-7. PubMed ID: 17873020
[TBL] [Abstract][Full Text] [Related]
9. Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation.
Lan X; Zhao C; Chen X; Zhang P; Zang D; Wu J; Chen J; Long H; Yang L; Huang H; Wang X; Shi X; Liu J
Cell Death Dis; 2017 Jul; 8(7):e2913. PubMed ID: 28682311
[TBL] [Abstract][Full Text] [Related]
10. Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination.
Huang Z; Nie L; Xu M; Sun XH
Mol Cell Biol; 2004 Oct; 24(20):8951-62. PubMed ID: 15456869
[TBL] [Abstract][Full Text] [Related]
11. Development of a Potent Protein Degrader against Oncogenic BCR-ABL Protein.
Shibata N; Ohoka N; Hattori T; Naito M
Chem Pharm Bull (Tokyo); 2019; 67(3):165-172. PubMed ID: 30827996
[TBL] [Abstract][Full Text] [Related]
12. Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides.
Aichberger KJ; Mayerhofer M; Krauth MT; Skvara H; Florian S; Sonneck K; Akgul C; Derdak S; Pickl WF; Wacheck V; Selzer E; Monia BP; Moriggl R; Valent P; Sillaber C
Blood; 2005 Apr; 105(8):3303-11. PubMed ID: 15626746
[TBL] [Abstract][Full Text] [Related]
13. Dual inhibition of Bcr-Abl and Hsp90 by C086 potently inhibits the proliferation of imatinib-resistant CML cells.
Wu L; Yu J; Chen R; Liu Y; Lou L; Wu Y; Huang L; Fan Y; Gao P; Huang M; Wu Y; Chen Y; Xu J
Clin Cancer Res; 2015 Feb; 21(4):833-43. PubMed ID: 25501124
[TBL] [Abstract][Full Text] [Related]
14. The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome.
An WG; Schulte TW; Neckers LM
Cell Growth Differ; 2000 Jul; 11(7):355-60. PubMed ID: 10939589
[TBL] [Abstract][Full Text] [Related]
15. Histone deacetylase inhibitor LAQ824 both lowers expression and promotes proteasomal degradation of Bcr-Abl and induces apoptosis of imatinib mesylate-sensitive or -refractory chronic myelogenous leukemia-blast crisis cells.
Nimmanapalli R; Fuino L; Bali P; Gasparetto M; Glozak M; Tao J; Moscinski L; Smith C; Wu J; Jove R; Atadja P; Bhalla K
Cancer Res; 2003 Aug; 63(16):5126-35. PubMed ID: 12941844
[TBL] [Abstract][Full Text] [Related]
16. The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins.
You L; Liu H; Huang J; Xie W; Wei J; Ye X; Qian W
Oncotarget; 2017 Jan; 8(5):7777-7790. PubMed ID: 27999193
[TBL] [Abstract][Full Text] [Related]
17. CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.
Urushitani M; Kurisu J; Tateno M; Hatakeyama S; Nakayama K; Kato S; Takahashi R
J Neurochem; 2004 Jul; 90(1):231-44. PubMed ID: 15198682
[TBL] [Abstract][Full Text] [Related]
18. Combination of panobinostat with ponatinib synergistically overcomes imatinib-resistant CML cells.
Matsuda Y; Yamauchi T; Hosono N; Uzui K; Negoro E; Morinaga K; Nishi R; Yoshida A; Kimura S; Maekawa T; Ueda T
Cancer Sci; 2016 Jul; 107(7):1029-38. PubMed ID: 27166836
[TBL] [Abstract][Full Text] [Related]
19. CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha.
Fan M; Park A; Nephew KP
Mol Endocrinol; 2005 Dec; 19(12):2901-14. PubMed ID: 16037132
[TBL] [Abstract][Full Text] [Related]
20. Ubiquitination and proteasomal degradation of nucleophosmin-anaplastic lymphoma kinase induced by 17-allylamino-demethoxygeldanamycin: role of the co-chaperone carboxyl heat shock protein 70-interacting protein.
Bonvini P; Dalla Rosa H; Vignes N; Rosolen A
Cancer Res; 2004 May; 64(9):3256-64. PubMed ID: 15126367
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
