BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

87 related articles for article (PubMed ID: 20676051)

  • 1. MAD2 downregulation in hypoxia is independent of promoter hypermethylation.
    Prencipe M; McGoldrick A; Perry AS; O'Grady A; Phelan S; McGrogan B; Fitzpatrick P; Watson JA; Furlong F; Brennan DJ; Lawler M; Kay E; McCann A
    Cell Cycle; 2010 Jul; 9(14):2856-65. PubMed ID: 20676051
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro.
    Prencipe M; Fitzpatrick P; Gorman S; Tosetto M; Klinger R; Furlong F; Harrison M; O'Connor D; Roninson IB; O'Sullivan J; McCann A
    Br J Cancer; 2009 Dec; 101(11):1900-8. PubMed ID: 19935801
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation.
    Lentini L; Barra V; Schillaci T; Di Leonardo A
    J Cell Physiol; 2012 Sep; 227(9):3324-32. PubMed ID: 22170163
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p31comet Induces cellular senescence through p21 accumulation and Mad2 disruption.
    Yun M; Han YH; Yoon SH; Kim HY; Kim BY; Ju YJ; Kang CM; Jang SH; Chung HY; Lee SJ; Cho MH; Yoon G; Park GH; Kim SH; Lee KH
    Mol Cancer Res; 2009 Mar; 7(3):371-82. PubMed ID: 19276188
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer.
    Nakamura J; Kitajima Y; Kai K; Hashiguchi K; Hiraki M; Noshiro H; Miyazaki K
    Am J Pathol; 2011 Feb; 178(2):515-24. PubMed ID: 21281785
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.
    Kaluzová M; Kaluz S; Lerman MI; Stanbridge EJ
    Mol Cell Biol; 2004 Jul; 24(13):5757-66. PubMed ID: 15199132
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines.
    Jakubicková L; Biesová Z; Pastoreková S; Kettmann R; Pastorek J
    Int J Oncol; 2005 Apr; 26(4):1121-7. PubMed ID: 15754010
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of Mad2 on paclitaxel-induced cell death in ovarian cancer cells.
    Hao X; Zhou Z; Ye S; Zhou T; Lu Y; Ma D; Wang S
    J Huazhong Univ Sci Technolog Med Sci; 2010 Oct; 30(5):620-5. PubMed ID: 21063845
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Depression of MAD2 inhibits apoptosis of gastric cancer cells by upregulating Bcl-2 and interfering mitochondrion pathway.
    Du Y; Yin F; Liu C; Hu S; Wang J; Xie H; Hong L; Fan D
    Biochem Biophys Res Commun; 2006 Jul; 345(3):1092-8. PubMed ID: 16714000
    [TBL] [Abstract][Full Text] [Related]  

  • 10. c-MYC delays prometaphase by direct transactivation of MAD2 and BubR1: identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability.
    Menssen A; Epanchintsev A; Lodygin D; Rezaei N; Jung P; Verdoodt B; Diebold J; Hermeking H
    Cell Cycle; 2007 Feb; 6(3):339-52. PubMed ID: 17297307
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia.
    Tafreshi NK; Lloyd MC; Proemsey JB; Bui MM; Kim J; Gillies RJ; Morse DL
    Mol Imaging Biol; 2016 Apr; 18(2):219-31. PubMed ID: 26276155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche.
    Lock FE; McDonald PC; Lou Y; Serrano I; Chafe SC; Ostlund C; Aparicio S; Winum JY; Supuran CT; Dedhar S
    Oncogene; 2013 Oct; 32(44):5210-9. PubMed ID: 23208505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MAD2 expression and its significance in mitotic checkpoint control in testicular germ cell tumour.
    Fung MK; Cheung HW; Wong HL; Yuen HF; Ling MT; Chan KW; Wong YC; Cheung AL; Wang X
    Biochim Biophys Acta; 2007 Jun; 1773(6):821-32. PubMed ID: 17467818
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models.
    Ward C; Meehan J; Mullen P; Supuran C; Dixon JM; Thomas JS; Winum JY; Lambin P; Dubois L; Pavathaneni NK; Jarman EJ; Renshaw L; Um IH; Kay C; Harrison DJ; Kunkler IH; Langdon SP
    Oncotarget; 2015 Sep; 6(28):24856-70. PubMed ID: 26259239
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation.
    Scott SA; Dong WF; Ichinohasama R; Hirsch C; Sheridan D; Sanche SE; Geyer CR; Decoteau JF
    Leuk Res; 2006 Jan; 30(1):69-76. PubMed ID: 16043219
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methylation of p16INK4A and mitotic arrest defective protein 2 (MAD2) genes in gastric marginal-zone B-cell lymphomas.
    Park S; Kim KM; Kim JJ; Lee JH; Rhee JC; Ko YH
    Acta Haematol; 2008; 120(4):217-24. PubMed ID: 19174606
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Downregulation of WIF-1 by hypermethylation in astrocytomas.
    Yang Z; Wang Y; Fang J; Chen F; Liu J; Wu J; Wang Y; Song T; Zeng F; Rao Y
    Acta Biochim Biophys Sin (Shanghai); 2010 Jun; 42(6):418-25. PubMed ID: 20539942
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Downregulation of BCL-2 induces downregulation of carbonic anhydrase IX, vascular endothelial growth factor, and pAkt and induces radiation sensitization.
    Anai S; Shiverick K; Medrano T; Nakamura K; Goodison S; Brown BD; Rosser CJ
    Urology; 2007 Oct; 70(4):832-7. PubMed ID: 17991582
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quantitative assessment of AKAP12 promoter methylation in colorectal cancer using methylation-sensitive high resolution melting: Correlation with Duke's stage.
    Liu W; Guan M; Su B; Ye C; Li J; Zhang X; Liu C; Li M; Lin Y; Lu Y
    Cancer Biol Ther; 2010 Jun; 9(11):862-71. PubMed ID: 20364105
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Upregulation of Mad2 facilitates in vivo and in vitro osteosarcoma progression.
    Yu L; Liu S; Guo W; Zhang B; Liang Y; Feng Q
    Oncol Rep; 2012 Dec; 28(6):2170-6. PubMed ID: 22992948
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.