BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

435 related articles for article (PubMed ID: 20679392)

  • 1. The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor.
    Manfredi JJ
    Genes Dev; 2010 Aug; 24(15):1580-9. PubMed ID: 20679392
    [TBL] [Abstract][Full Text] [Related]  

  • 2. microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.
    Zhang C; Liu J; Tan C; Yue X; Zhao Y; Peng J; Wang X; Laddha SV; Chan CS; Zheng S; Hu W; Feng Z
    Oncotarget; 2016 Feb; 7(8):8783-96. PubMed ID: 26840028
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The regulation of MDM2 oncogene and its impact on human cancers.
    Zhao Y; Yu H; Hu W
    Acta Biochim Biophys Sin (Shanghai); 2014 Mar; 46(3):180-9. PubMed ID: 24389645
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The roles and regulation of MDM2 and MDMX: it is not just about p53.
    Klein AM; de Queiroz RM; Venkatesh D; Prives C
    Genes Dev; 2021 May; 35(9-10):575-601. PubMed ID: 33888565
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mdmx and Mdm2: brothers in arms?
    Marine JC; Jochemsen AG
    Cell Cycle; 2004 Jul; 3(7):900-4. PubMed ID: 15254433
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The in vivo role of the RP-Mdm2-p53 pathway in signaling oncogenic stress induced by pRb inactivation and Ras overexpression.
    Pan W; Issaq S; Zhang Y
    PLoS One; 2011; 6(6):e21625. PubMed ID: 21747916
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo.
    Comiskey DF; Jacob AG; Sanford BL; Montes M; Goodwin AK; Steiner H; Matsa E; Tapia-Santos AS; Bebee TW; Grieves J; La Perle K; Boyaka P; Chandler DS
    Oncogene; 2018 Jan; 37(1):95-106. PubMed ID: 28892044
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ablation of Cancer Stem Cells by Therapeutic Inhibition of the MDM2-p53 Interaction in Mucoepidermoid Carcinoma.
    Andrews A; Warner K; Rodriguez-Ramirez C; Pearson AT; Nör F; Zhang Z; Kerk S; Kulkarni A; Helman JI; Brenner JC; Wicha MS; Wang S; Nör JE
    Clin Cancer Res; 2019 Mar; 25(5):1588-1600. PubMed ID: 30498096
    [TBL] [Abstract][Full Text] [Related]  

  • 9. miR-339-5p regulates the p53 tumor-suppressor pathway by targeting MDM2.
    Jansson MD; Damas ND; Lees M; Jacobsen A; Lund AH
    Oncogene; 2015 Apr; 34(15):1908-18. PubMed ID: 24882579
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Angiogenic factor AGGF1 acts as a tumor suppressor by modulating p53 post-transcriptional modifications and stability via MDM2.
    Si W; Zhou B; Xie W; Li H; Li K; Li S; Deng W; Shi P; Yuan C; Ke T; Ren X; Tu X; Zeng X; Weigelt B; Rubin BP; Chen Q; Xu C; Wang QK
    Cancer Lett; 2021 Jan; 497():28-40. PubMed ID: 33069768
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
    Okamoto K; Taya Y; Nakagama H
    FEBS Lett; 2009 Sep; 583(17):2710-4. PubMed ID: 19619542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
    Zhang XW; Wang XF; Ni SJ; Qin W; Zhao LQ; Hua RX; Lu YW; Li J; Dimri GP; Guo WJ
    J Pathol; 2015 Mar; 235(4):656-67. PubMed ID: 25382750
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mdm2-mediated ubiquitylation: p53 and beyond.
    Marine JC; Lozano G
    Cell Death Differ; 2010 Jan; 17(1):93-102. PubMed ID: 19498444
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells.
    Davies L; Spiller D; White MR; Grierson I; Paraoan L
    Cell Death Dis; 2011 Mar; 2(3):e136. PubMed ID: 21451571
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent advances in validating MDM2 as a cancer target.
    Rayburn ER; Ezell SJ; Zhang R
    Anticancer Agents Med Chem; 2009 Oct; 9(8):882-903. PubMed ID: 19538162
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53.
    Wienken M; Dickmanns A; Nemajerova A; Kramer D; Najafova Z; Weiss M; Karpiuk O; Kassem M; Zhang Y; Lozano G; Johnsen SA; Moll UM; Zhang X; Dobbelstein M
    Mol Cell; 2016 Jan; 61(1):68-83. PubMed ID: 26748827
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of the p14ARF-Mdm2-p53 pathway: an overview in breast cancer.
    Agrawal A; Yang J; Murphy RF; Agrawal DK
    Exp Mol Pathol; 2006 Oct; 81(2):115-22. PubMed ID: 16919268
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mdm2 widens its repertoire.
    Coutts AS; La Thangue NB
    Cell Cycle; 2007 Apr; 6(7):827-9. PubMed ID: 17377491
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MDM2-p53 pathway in hepatocellular carcinoma.
    Meng X; Franklin DA; Dong J; Zhang Y
    Cancer Res; 2014 Dec; 74(24):7161-7. PubMed ID: 25477334
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Significance of MDM2 protein in the cell cycle].
    Szemraj J; Rozpończyk E; Bartkowiak J; Greger J; Oszajca K
    Postepy Biochem; 2005; 51(1):44-51. PubMed ID: 16209341
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.