BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 20679487)

  • 1. VRK2 inhibits mitogen-activated protein kinase signaling and inversely correlates with ErbB2 in human breast cancer.
    Fernández IF; Blanco S; Lozano J; Lazo PA
    Mol Cell Biol; 2010 Oct; 30(19):4687-97. PubMed ID: 20679487
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.
    Yuen HF; Chan KK; Grills C; Murray JT; Platt-Higgins A; Eldin OS; O'Byrne K; Janne P; Fennell DA; Johnston PG; Rudland PS; El-Tanani M
    Clin Cancer Res; 2012 Jan; 18(2):380-91. PubMed ID: 22090358
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways.
    Gu J; Tamura M; Yamada KM
    J Cell Biol; 1998 Nov; 143(5):1375-83. PubMed ID: 9832564
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects.
    Jackson JG; St Clair P; Sliwkowski MX; Brattain MG
    Cancer Res; 2004 Apr; 64(7):2601-9. PubMed ID: 15059917
    [TBL] [Abstract][Full Text] [Related]  

  • 5. VRK2 anchors KSR1-MEK1 to endoplasmic reticulum forming a macromolecular complex that compartmentalizes MAPK signaling.
    Fernández IF; Pérez-Rivas LG; Blanco S; Castillo-Dominguez AA; Lozano J; Lazo PA
    Cell Mol Life Sci; 2012 Nov; 69(22):3881-93. PubMed ID: 22752157
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells.
    Arias-Romero LE; Villamar-Cruz O; Pacheco A; Kosoff R; Huang M; Muthuswamy SK; Chernoff J
    Oncogene; 2010 Oct; 29(43):5839-49. PubMed ID: 20711231
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.
    Park JI; Strock CJ; Ball DW; Nelkin BD
    Mol Cell Biol; 2003 Jan; 23(2):543-54. PubMed ID: 12509453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cells.
    Aksamitiene E; Kholodenko BN; Kolch W; Hoek JB; Kiyatkin A
    Cell Signal; 2010 Sep; 22(9):1369-78. PubMed ID: 20471474
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epidermal growth factor receptor, c-erbB2 and c-erbB3 receptor interaction, and related cell cycle kinetics of SK-BR-3 and BT474 breast carcinoma cells.
    Brockhoff G; Heiss P; Schlegel J; Hofstaedter F; Knuechel R
    Cytometry; 2001 Aug; 44(4):338-48. PubMed ID: 11500850
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclic stretch activates p38 SAPK2-, ErbB2-, and AT1-dependent signaling in bladder smooth muscle cells.
    Nguyen HT; Adam RM; Bride SH; Park JM; Peters CA; Freeman MR
    Am J Physiol Cell Physiol; 2000 Oct; 279(4):C1155-67. PubMed ID: 11003596
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Paclitaxel induces prolonged activation of the Ras/MEK/ERK pathway independently of activating the programmed cell death machinery.
    Okano J ; Rustgi AK
    J Biol Chem; 2001 Jun; 276(22):19555-64. PubMed ID: 11278851
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epidermal Growth Factor Receptor Signaling to the Mitogen Activated Protein Kinase Pathway Bypasses Ras in Pancreatic Cancer Cells.
    Lee S; Heinrich EL; Lu J; Lee W; Choi AH; Luu C; Chung V; Fakih M; Kim J
    Pancreas; 2016 Feb; 45(2):286-92. PubMed ID: 26262587
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sphingosine 1-phosphate receptor 4 uses HER2 (ERBB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast cancer cells.
    Long JS; Fujiwara Y; Edwards J; Tannahill CL; Tigyi G; Pyne S; Pyne NJ
    J Biol Chem; 2010 Nov; 285(46):35957-66. PubMed ID: 20837468
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cas mediates transcriptional activation of the serum response element by Src.
    Hakak Y; Martin GS
    Mol Cell Biol; 1999 Oct; 19(10):6953-62. PubMed ID: 10490632
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RAF1/BRAF dimerization integrates the signal from RAS to ERK and ROKα.
    Varga A; Ehrenreiter K; Aschenbrenner B; Kocieniewski P; Kochanczyk M; Lipniacki T; Baccarini M
    Sci Signal; 2017 Mar; 10(469):. PubMed ID: 28270557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Radicicol suppresses transformation and restores tropomyosin-2 expression in both ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade.
    Kim PN; Jonasch E; Mosterman BC; Mier JW; Janssen RA
    Cell Growth Differ; 2001 Nov; 12(11):543-50. PubMed ID: 11714635
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased expression of epidermal growth factor receptor induces sequestration of extracellular signal-related kinases and selective attenuation of specific epidermal growth factor-mediated signal transduction pathways.
    Habib AA; Chun SJ; Neel BG; Vartanian T
    Mol Cancer Res; 2003 Jan; 1(3):219-33. PubMed ID: 12556561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors.
    Beeser A; Jaffer ZM; Hofmann C; Chernoff J
    J Biol Chem; 2005 Nov; 280(44):36609-15. PubMed ID: 16129686
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner.
    Joseph EW; Pratilas CA; Poulikakos PI; Tadi M; Wang W; Taylor BS; Halilovic E; Persaud Y; Xing F; Viale A; Tsai J; Chapman PB; Bollag G; Solit DB; Rosen N
    Proc Natl Acad Sci U S A; 2010 Aug; 107(33):14903-8. PubMed ID: 20668238
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.