190 related articles for article (PubMed ID: 20685848)
1. Structure-activity relationships of GPR120 agonists based on a docking simulation.
Sun Q; Hirasawa A; Hara T; Kimura I; Adachi T; Awaji T; Ishiguro M; Suzuki T; Miyata N; Tsujimoto G
Mol Pharmacol; 2010 Nov; 78(5):804-10. PubMed ID: 20685848
[TBL] [Abstract][Full Text] [Related]
2. FFA1-selective agonistic activity based on docking simulation using FFA1 and GPR120 homology models.
Takeuchi M; Hirasawa A; Hara T; Kimura I; Hirano T; Suzuki T; Miyata N; Awaji T; Ishiguro M; Tsujimoto G
Br J Pharmacol; 2013 Apr; 168(7):1570-83. PubMed ID: 22639973
[TBL] [Abstract][Full Text] [Related]
3. Novel selective ligands for free fatty acid receptors GPR120 and GPR40.
Hara T; Hirasawa A; Sun Q; Sadakane K; Itsubo C; Iga T; Adachi T; Koshimizu TA; Hashimoto T; Asakawa Y; Tsujimoto G
Naunyn Schmiedebergs Arch Pharmacol; 2009 Sep; 380(3):247-55. PubMed ID: 19471906
[TBL] [Abstract][Full Text] [Related]
4. Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists.
Lavecchia A; Cosconati S; Novellino E
J Med Chem; 2005 Apr; 48(7):2480-92. PubMed ID: 15801838
[TBL] [Abstract][Full Text] [Related]
5. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
Bhattacharya S; Hall SE; Vaidehi N
J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
[TBL] [Abstract][Full Text] [Related]
6. A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice.
Bianchini G; Nigro C; Sirico A; Novelli R; Prevenzano I; Miele C; Beguinot F; Aramini A
Biomed Pharmacother; 2021 Jul; 139():111613. PubMed ID: 33895521
[TBL] [Abstract][Full Text] [Related]
7. The acute glucose lowering effect of specific GPR120 activation in mice is mainly driven by glucagon-like peptide 1.
Sundström L; Myhre S; Sundqvist M; Ahnmark A; McCoull W; Raubo P; Groombridge SD; Polla M; Nyström AC; Kristensson L; Någård M; Winzell MS
PLoS One; 2017; 12(12):e0189060. PubMed ID: 29206860
[TBL] [Abstract][Full Text] [Related]
8. Molecular docking and molecular dynamics simulation studies of GPR40 receptor-agonist interactions.
Lu SY; Jiang YJ; Lv J; Wu TX; Yu QS; Zhu WL
J Mol Graph Model; 2010 Jun; 28(8):766-74. PubMed ID: 20227312
[TBL] [Abstract][Full Text] [Related]
9. Expanding GPCR homology model binding sites via a balloon potential: A molecular dynamics refinement approach.
Kimura SR; Tebben AJ; Langley DR
Proteins; 2008 Jun; 71(4):1919-29. PubMed ID: 18175323
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity.
Anzini M; Canullo L; Braile C; Cappelli A; Gallelli A; Vomero S; Menziani MC; De Benedetti PG; Rizzo M; Collina S; Azzolina O; Sbacchi M; Ghelardini C; Galeotti N
J Med Chem; 2003 Aug; 46(18):3853-64. PubMed ID: 12930147
[TBL] [Abstract][Full Text] [Related]
11. Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.
Katsuma S; Hatae N; Yano T; Ruike Y; Kimura M; Hirasawa A; Tsujimoto G
J Biol Chem; 2005 May; 280(20):19507-15. PubMed ID: 15774482
[TBL] [Abstract][Full Text] [Related]
12. Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.
Katsuma S; Hirasawa A; Tsujimoto G
Biochem Biophys Res Commun; 2005 Apr; 329(1):386-90. PubMed ID: 15721318
[TBL] [Abstract][Full Text] [Related]
13. GPR120 agonists for the treatment of diabetes: a patent review (2014 present).
Zhang X; Macielag MJ
Expert Opin Ther Pat; 2020 Oct; 30(10):729-742. PubMed ID: 32799609
[TBL] [Abstract][Full Text] [Related]
14. An evaluation of automated in silico ligand docking of amino acid ligands to Family C G-protein coupled receptors.
Wang M; Hampson DR
Bioorg Med Chem; 2006 Mar; 14(6):2032-9. PubMed ID: 16297630
[TBL] [Abstract][Full Text] [Related]
15. Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells.
Tanaka T; Yano T; Adachi T; Koshimizu TA; Hirasawa A; Tsujimoto G
Naunyn Schmiedebergs Arch Pharmacol; 2008 Jun; 377(4-6):515-22. PubMed ID: 18320172
[TBL] [Abstract][Full Text] [Related]
16. Homology models of the cannabinoid CB1 and CB2 receptors. A docking analysis study.
Montero C; Campillo NE; Goya P; Páez JA
Eur J Med Chem; 2005 Jan; 40(1):75-83. PubMed ID: 15642412
[TBL] [Abstract][Full Text] [Related]
17. Molecular modeling aided design of nicotinic acid receptor GPR109A agonists.
Deng Q; Frie JL; Marley DM; Beresis RT; Ren N; Cai TQ; Taggart AK; Cheng K; Carballo-Jane E; Wang J; Tong X; Waters MG; Tata JR; Colletti SL
Bioorg Med Chem Lett; 2008 Sep; 18(18):4963-7. PubMed ID: 18760600
[TBL] [Abstract][Full Text] [Related]
18. Identification of G protein-coupled receptor 120-selective agonists derived from PPARgamma agonists.
Suzuki T; Igari S; Hirasawa A; Hata M; Ishiguro M; Fujieda H; Itoh Y; Hirano T; Nakagawa H; Ogura M; Makishima M; Tsujimoto G; Miyata N
J Med Chem; 2008 Dec; 51(23):7640-4. PubMed ID: 19007110
[TBL] [Abstract][Full Text] [Related]
19. First pharmacophore model of CCR3 receptor antagonists and its homology model-assisted, stepwise virtual screening.
Jain V; Saravanan P; Arvind A; Mohan CG
Chem Biol Drug Des; 2011 May; 77(5):373-87. PubMed ID: 21284830
[TBL] [Abstract][Full Text] [Related]
20. Delineation of agonist binding to the human histamine H4 receptor using mutational analysis, homology modeling, and ab initio calculations.
Jongejan A; Lim HD; Smits RA; de Esch IJ; Haaksma E; Leurs R
J Chem Inf Model; 2008 Jul; 48(7):1455-63. PubMed ID: 18553960
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
