These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
309 related articles for article (PubMed ID: 20686448)
1. Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease. Zafar I; Ravichandran K; Belibi FA; Doctor RB; Edelstein CL Kidney Int; 2010 Oct; 78(8):754-61. PubMed ID: 20686448 [TBL] [Abstract][Full Text] [Related]
2. Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD). Wahl PR; Serra AL; Le Hir M; Molle KD; Hall MN; Wüthrich RP Nephrol Dial Transplant; 2006 Mar; 21(3):598-604. PubMed ID: 16221708 [TBL] [Abstract][Full Text] [Related]
3. A study of sirolimus and mTOR kinase inhibitor in a hypomorphic Holditch SJ; Brown CN; Atwood DJ; Lombardi AM; Nguyen KN; Toll HW; Hopp K; Edelstein CL Am J Physiol Renal Physiol; 2019 Jul; 317(1):F187-F196. PubMed ID: 31042058 [TBL] [Abstract][Full Text] [Related]
4. An mTOR anti-sense oligonucleotide decreases polycystic kidney disease in mice with a targeted mutation in Pkd2. Ravichandran K; Zafar I; He Z; Doctor RB; Moldovan R; Mullick AE; Edelstein CL Hum Mol Genet; 2014 Sep; 23(18):4919-31. PubMed ID: 24847003 [TBL] [Abstract][Full Text] [Related]
5. Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1/cyclin axis. Li A; Fan S; Xu Y; Meng J; Shen X; Mao J; Zhang L; Zhang X; Moeckel G; Wu D; Wu G; Liang C J Cell Mol Med; 2017 Aug; 21(8):1619-1635. PubMed ID: 28244683 [TBL] [Abstract][Full Text] [Related]
6. Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease. Weisser I; Eckberg K; D'Amico S; Buttram D; Aboudehen K J Am Soc Nephrol; 2024 Jan; 35(1):41-55. PubMed ID: 37953472 [TBL] [Abstract][Full Text] [Related]
7. Impact of mammalian target of rapamycin inhibition on autosomal-dominant polycystic kidney disease. Wüthrich RP; Kistler AD; Serra AL Transplant Proc; 2010 Nov; 42(9 Suppl):S44-6. PubMed ID: 21095452 [TBL] [Abstract][Full Text] [Related]
8. Sirolimus reduces polycystic liver volume in ADPKD patients. Qian Q; Du H; King BF; Kumar S; Dean PG; Cosio FG; Torres VE J Am Soc Nephrol; 2008 Mar; 19(3):631-8. PubMed ID: 18199797 [TBL] [Abstract][Full Text] [Related]
9. Double inhibition of cAMP and mTOR signalling may potentiate the reduction of cell growth in ADPKD cells. de Stephanis L; Bonon A; Varani K; Lanza G; Gafà R; Pinton P; Pema M; Somlo S; Boletta A; Aguiari G Clin Exp Nephrol; 2017 Apr; 21(2):203-211. PubMed ID: 27278932 [TBL] [Abstract][Full Text] [Related]
11. Early treatment with 2-deoxy-d-glucose reduces proliferative proteins in the kidney and slows cyst growth in a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease (PKD). Atwood D; He Z; Miyazaki M; Hailu F; Klawitter J; Edelstein CL Cell Signal; 2024 Nov; 123():111351. PubMed ID: 39159908 [TBL] [Abstract][Full Text] [Related]
12. Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease. Kipp KR; Kruger SL; Schimmel MF; Parker N; Shillingford JM; Leamon CP; Weimbs T Am J Physiol Renal Physiol; 2018 Aug; 315(2):F395-F405. PubMed ID: 29717938 [TBL] [Abstract][Full Text] [Related]
13. Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model. Leonhard WN; van der Wal A; Novalic Z; Kunnen SJ; Gansevoort RT; Breuning MH; de Heer E; Peters DJ Am J Physiol Renal Physiol; 2011 May; 300(5):F1193-202. PubMed ID: 21345977 [TBL] [Abstract][Full Text] [Related]
14. Metformin improves relevant disease parameters in an autosomal dominant polycystic kidney disease mouse model. Pastor-Soler NM; Li H; Pham J; Rivera D; Ho PY; Mancino V; Saitta B; Hallows KR Am J Physiol Renal Physiol; 2022 Jan; 322(1):F27-F41. PubMed ID: 34806449 [TBL] [Abstract][Full Text] [Related]
15. Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus. Stayner C; Shields J; Slobbe L; Shillingford JM; Weimbs T; Eccles MR Nephrology (Carlton); 2012 Nov; 17(8):739-47. PubMed ID: 22725947 [TBL] [Abstract][Full Text] [Related]
16. Everolimus in patients with autosomal dominant polycystic kidney disease. Walz G; Budde K; Mannaa M; Nürnberger J; Wanner C; Sommerer C; Kunzendorf U; Banas B; Hörl WH; Obermüller N; Arns W; Pavenstädt H; Gaedeke J; Büchert M; May C; Gschaidmeier H; Kramer S; Eckardt KU N Engl J Med; 2010 Aug; 363(9):830-40. PubMed ID: 20581392 [TBL] [Abstract][Full Text] [Related]
17. Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease. Tao Y; Kim J; Schrier RW; Edelstein CL J Am Soc Nephrol; 2005 Jan; 16(1):46-51. PubMed ID: 15563559 [TBL] [Abstract][Full Text] [Related]
18. A mild reduction of food intake slows disease progression in an orthologous mouse model of polycystic kidney disease. Kipp KR; Rezaei M; Lin L; Dewey EC; Weimbs T Am J Physiol Renal Physiol; 2016 Apr; 310(8):F726-F731. PubMed ID: 26764208 [TBL] [Abstract][Full Text] [Related]
19. mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease. Belibi F; Ravichandran K; Zafar I; He Z; Edelstein CL Am J Physiol Renal Physiol; 2011 Jan; 300(1):F236-44. PubMed ID: 20943770 [TBL] [Abstract][Full Text] [Related]
20. Antisense-mediated angiotensinogen inhibition slows polycystic kidney disease in mice with a targeted mutation in Pkd2. Ravichandran K; Ozkok A; Wang Q; Mullick AE; Edelstein CL Am J Physiol Renal Physiol; 2015 Feb; 308(4):F349-57. PubMed ID: 25537744 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]